An observational study in Ventricular Arrhythmia, Ventricular Tachycardia and Premature Ventricular Contraction (PVC), sponsored by University of California, Los Angeles. Enrolling by invitation at 41 sites in 7 countries. Per ClinicalTrials.gov, last updated 2025-12-15.
Sponsored by University of California, Los Angeles · Observational
This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular Contractions (PVC). The registry will be used for clinical monitoring, research, and quality improvement purposes.
Sudden cardiac death (SCD), predominantly due to ventricular tachyarrhythmias, is a leading cause of mortality in the United States and around the world. Catheter ablation of ventricular arrhythmias has proven efficacious in reducing the burden of arrhythmias and reducing implantable cardiac defibrillator (ICD) shocks.
The aim of this study is to create a prospective international database registry that will allow for better assessment of the outcomes of catheter ablation of ventricular arrhythmias. The registry, with approximately 30 participating centers, will help to identify the overall success rates and associated benefits of the procedure and provide more comprehensive data on understudied populations and treatment.
Patients with ventricular arrhythmias that undergo catheter ablation for ventricular tachycardia or premature ventricular contractions.
Inclusion Criteria:
- All patients undergoing catheter ablation for ventricular tachycardia (VT) or premature ventricular contractions (PVCs).
Ventricular tachycardia (VT) recurrence
Freedom from ventricular tachycardia episodes requiring ICD Intervention (shock or Anti-Tachycardia Pacing) or repeat procedure.
Time frame: From date of procedure assessed by shock, Anti-Tachycardia Pacing, or repeat procedure, up to 10 years.
Rate of complications
Cardiovascular-related and procedure-related major complications and/or adverse events.
Time frame: From date of procedure assessed up to 12 months.
Time to transplant or death
Time frame: From date of procedure assessed by date of transplant and/or death, up to 10 years.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
No contact was published for this record. The registry link below has the sponsor’s details.
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University of California, Los Angeles