Cardiomyopathy, Dilated clinical trials
The registry lists 255 studies for Cardiomyopathy, Dilated across more than 10 countries. 66 are recruiting or about to start. 168 of them are mainly about Cardiomyopathy, Dilated (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Imperial College London (9) · University Medical Centre Ljubljana (6) · LoneStar Heart, Inc. (4) · Assiut University (4) · AstraZeneca (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · University Hospital Heidelberg (3) · University Hospital, Bordeaux (3)
What is being tested here
Drugs under test in Cardiomyopathy, Dilated studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Empagliflozin | 1 | 0 | 1 |
| Candesartan | 1 | 1 | 1 |
| Sirolimus | 1 | 0 | 1 |
| Carvedilol | 0 | 0 | 3 |
| Ivabradine | 0 | 0 | 2 |
| Metoprolol | 0 | 0 | 2 |
| Danicamtiv | 0 | 0 | 2 |
| Solizmestrocel | 0 | 0 | 2 |
| Granulocyte Colony-Stimulating Factor | 0 | 1 | 2 |
| Ifetroban | 0 | 0 | 1 |
Drug classes tested here Beta blockers 5 · ACE inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy · Phase 3 · Kardigan, Inc.
- Dec 2026Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study · Ohio State University
- Dec 2026Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT) · Lancaster General Hospital
- Dec 2026The Application of T1 Mapping in Real-World · Chinese Academy of Medical Sciences, Fuwai Hospital
- Dec 2026the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients · Ain Shams University
- Dec 2026A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease · McGill University Health Centre/Research Institute of the McGill University Health Centre
- Dec 2026Effect of Sildenafil on Left Ventricular Function in Pediatric With Primary Dilated Cardiomyopathy · Assiut University
- Dec 2026Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM) · Wuhan Union Hospital, China
- Jan 2027MyocarditIRM-Génétique - Genetic Sub-study of the French Cohort of Acute Myocarditis Cases Diagnosed by MRI · French Cardiology Society
- Jan 2027Registry of Cell Therapy in Non-Ischemic Dilated Cardiomyopathy · University Medical Centre Ljubljana
Who these studies take
Of the 53 Cardiomyopathy, Dilated studies recruiting now, 30 (57%) set no upper age limit and 15 (28%) stop at 75 or younger. 13 (25%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 9 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 10 (19%) | 10 (19%) |
| 18 | 51 (96%) | 50 (94%) |
| 30 | 52 (98%) | 51 (96%) |
| 40 | 51 (96%) | 50 (94%) |
| 50 | 50 (94%) | 49 (92%) |
| 65 | 48 (91%) | 48 (91%) |
| 75 | 43 (81%) | 43 (81%) |
| 85 | 34 (64%) | 34 (64%) |
Across all 255 studies, recruiting or not: 34% stop at 75 or younger and 20% at 65; 27% take children; 1% are for women only and 2% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cardiomyopathy, Dilated studies take
Of 50 observational studies under Cardiomyopathy, Dilated, half reached primary completion within 95 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 46 mo31–73 · 28 studies | — | — |
| Observational | 95 mo51–101 · 50 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Newly registered1
- Focal Pulsed Field Ablation of Ventricular TachycardiaNov 10, 2026NCT07929545
Studies
Recruiting first, then most recently updated. Showing 50 of 255. Browse all 255 → or search them.
- Focal Pulsed Field Ablation of Ventricular TachycardiaEnrolling by invitationNCT079295451 country
- The Application of T1 Mapping in Real-WorldRecruitingNCT073546461 country
- A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated CardiomyopathyRecruitingNCT07771465Phase 311 countries
- A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated CardiomyopathyRecruitingNCT07210723Phase 2/311 countries
- A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac DiseaseRecruitingNCT044646551 country
- An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)RecruitingNCT07426419Phase 1/22 countries
- Observational Study of Natural History of BAG3 Gene Mutation-Associated Dilated Cardiomyopathy in Chinese AdultsRecruitingNCT076466001 country
- Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study)RecruitingNCT07347197Phase 1/21 country
- BAG3-DCM Natural History StudyNot yet recruitingNCT07486752
- A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated CardiomyopathyRecruitingNCT07137338Phase 11 country
- RHYthm and Myocardial Function Relationship Evaluation in Heart DiseasesRecruitingNCT074912371 country
- A Study of AZD4063 in PLN R14del Dilated CardiomyopathyRecruitingNCT07241104Phase 11 country
- ALXN2350 in Adult Participants With BAG3-Associated Dilated CardiomyopathyRecruitingNCT07218887Phase 1/24 countries
- Study of the Progression of Chronic Cardiovascular ConditionsRecruitingNCT074209071 country
- Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular LeadRecruitingNCT06920030Not applicable2 countries
- A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)RecruitingNCT07606274Phase 1/21 country
- Safety and Efficacy of FAP iCDC in End-stage Dilated CardiomyopathyRecruitingNCT06902896Phase 1/21 country
- the Clinical Outcome of Empagliflozin in Pediatric Heart Failure PatientsRecruitingNCT07692256Phase 21 country
- Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated CardiomyopathyRecruitingNCT07516288Phase 11 country
- A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)RecruitingNCT06464588Phase 11 country
- Pediatric Cardiomyopathy Mutation AnalysisRecruitingNCT024320921 country
- AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable MonitorRecruitingNCT066990561 country
- National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter RegistryRecruitingNCT065461371 country
- Mainstreaming Genetic Testing for Non-Ischemic Cardiomyopathy in Western CanadaEnrolling by invitationNCT07345338Not applicable1 country
- Endocrinal Dysfunction Among Children With Dilated CardiomyopathyNot yet recruitingNCT07567417Not applicable1 country
- Effect of Sildenafil on Left Ventricular Function in Pediatric With Primary Dilated CardiomyopathyNot yet recruitingNCT07536880
- Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated CardiomyopathyRecruitingNCT075277151 country
- The Heart Hive - Cardiomyopathy StudyRecruitingNCT046122961 country
- Modifying Factors in Striated Muscle LaminopathiesRecruitingNCT05394506Not applicable1 country
- Multimodal Analysis of Endomyocardial BiopsiesRecruitingNCT073596901 country
- Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac ArrhythmiasEnrolling by invitationNCT024134501 country
- Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated CardiomyopathyRecruitingNCT072933381 country
- Phenotypic Classification of FMR With CMRRecruitingNCT059652581 country
- Comparative Efficacy of ARNI Versus ACE Inhibitor Therapy in Egyptian Children With Dilated CardiomyopathyNot yet recruitingNCT07197372
- UIC Multi-Ethnic DCM RegistryRecruitingNCT071451381 country
- Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization TherapyRecruitingNCT055646891 country
- Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM)RecruitingNCT06922851Not applicable1 country
- Evaluating the Prognostic Impact of Anti-β1AR Antibodies and Anti-L-CaC Antibodies in Patients With Dilated CardiomyopathyRecruitingNCT067419951 country
- Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac TransplantationRecruitingNCT068134431 country
- Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)RecruitingNCT06688396Not applicable1 country
- Early Identification and Treatment of Rare Cardiomyopathy CohortsNot yet recruitingNCT06794710Not applicable1 country
- AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTANot yet recruitingNCT06748261
- Image-Based Prediction of Ventricular Tachycardia Events in Non-ischemic CardiomyopathyRecruitingNCT067304643 countries
- Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive AgeRecruitingNCT06250257Phase 31 country
- Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial)RecruitingNCT05321875Phase 31 country
- Outcome-targeted Therapy: Principle and Outcome Evaluation: Clinical Study and Phenotype-genotype CorrelationRecruitingNCT06632834Phase 21 country
- Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.RecruitingNCT066074711 country
- Therapy to Maintain Remission in Dilated CardiomyopathyRecruitingNCT06091475Not applicable1 country
- Registry of Cell Therapy in Non-Ischemic Dilated CardiomyopathyRecruitingNCT024455341 country
- IntelliStent for Pulmonary Flow Adjustment in Congenital Heart Disease and Dilated CardiomyopathyNot yet recruitingNCT06072937Not applicable