Drug
Trimethoprim clinical trials
- studies test it
- 32
- open now
- 4
- in phase 3
- 8
- first study started
- 1997
Keep track of what changes. Save the Trimethoprim studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Brand
Studies by the year they started
18 studies that test it; most in 2010 (3)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2001 | 1 |
| 2003 | 1 |
| 2006 | 2 |
| 2010 | 3 |
| 2013 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2018 | 1 |
| 2022 | 1 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 5
- Phase 3
- 8
- Phase 4
- 5
- No phase
- 9
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 28
National Institute of Allergy and Infectious Diseases (NIAID) (12) · McMaster University (1) · Endeavor Health (1) · The Hospital for Sick Children (1) · GlaxoSmithKline (1) · Texas Tech University Health Sciences Center (1) · Gary Morrow (1) · IRCCS Burlo Garofolo (1)
Often tested with
Tested in the same studies.
Sulfamethoxazole (24) · Dapsone (4) · Ciprofloxacin (3) · Leucovorin (2) · Clindamycin (2) · Zidovudine (2) · Linezolid (2) · Doxycycline (2)
Studies
Open first, then newest update. How each study uses Trimethoprim is read from its arms, and is right about nine times in ten.
Testing it · 32
- Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary InfectionEnrolling by invitationPhase 1Vancouver Coastal HealthNCT07228702Written as Sulfamethoxazole/Trimethoprim
- Folate Study in Men With Advanced Prostate CancerNot yet recruitingPhase 2University of California, San DiegoNCT06536374Written as Trimethoprim Tablets
- MRSA Decolonization in Complicated CarriageRecruitingNot applicableLeiden University Medical CenterNCT05268120Written as trimethoprim 200mg b.i.d. - rifampicin 600mg b.i.d.
- Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric ProphylaxisRecruitingPhase 4Rigshospitalet, DenmarkNCT06709196Written as Trimethoprim
- Effectiveness of Antibiotics Versus Placebo to Treat Antenatal HydronephrosisActive, not recruitingNot applicableMcMaster UniversityNCT01140516Written as Trimethoprim
- S. Aureus Decolonization in HPN Patients.TerminatedNot applicableRadboud University Medical CenterNCT03173053Written as Trimethoprim
- A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected PatientsCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000748Written as Sulfamethoxazole-Trimethoprim
- Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia ProphylaxisCompletedPhase 4National Institute of Allergy and Infectious Diseases (NIAID)NCT00000816Written as Sulfamethoxazole-Trimethoprim
- Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00001013Written as Sulfamethoxazole-Trimethoprim
- Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00001014Written as Sulfamethoxazole-Trimethoprim
- A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)CompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000727Written as Sulfamethoxazole/Trimethoprim
- A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDSCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000640Written as Sulfamethoxazole-Trimethoprim
- Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and ZidovudineCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00000732Written as Sulfamethoxazole-Trimethoprim
- A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDSCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000715Written as Sulfamethoxazole-Trimethoprim
- Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine MetabolitesCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00000826Written as Sulfamethoxazole-Trimethoprim
- Evaluation of the Interaction Between High Dose Sulfamethoxazole/Trimethoprim and ZidovudineCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00000734Written as Sulfamethoxazole-Trimethoprim
- Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIsCompletedPhase 4Endeavor HealthNCT03077711Written as Trimethoprim
- The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis BullosaCompletedPhase 2The Hospital for Sick ChildrenNCT00380640Written as Trimethoprim
- Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult VolunteersCompletedPhase 1GlaxoSmithKlineNCT02371603Written as Trimethoprim 100 mg Tablet
- Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim ConcentrationsCompletedPhase 4Texas Tech University Health Sciences CenterNCT01167452Written as Sulfamethoxazole/trimethoprim
See all 32 studies that test Trimethoprim →
Given in every arm · 4 — Trimethoprim is usual care beside what is tested
- A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)RecruitingPhase 2Locus BiosciencesNCT05488340Written as TMP/SMX
- Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2DActive, not recruitingPhase 1/2Atsena Therapeutics Inc.NCT03920007Written as Trimethoprim/polymyxin B
- The Effect of SLC19A3 Inhibition on the Pharmacokinetics of ThiamineCompletedPhase 4University of California, San FranciscoNCT03746106Written as Trimethoprim
- Steroid-Free Versus Steroid-Based Immunosuppression in Pediatric Renal (Kidney) TransplantationCompletedPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT00141037Written as Trimethoprim and sulfamethoxazole
As the comparator · 3 — what is tested is compared with Trimethoprim
- Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective EndocarditisRecruitingPhase 4Fundacion Clinic per a la Recerca BiomédicaNCT05398679Written as Sulfamethoxazole / Trimethoprim Injectable Product
- Single Dose Monurol for Treatment of Acute CystitisCompletedNot applicableUniversity of WashingtonNCT00976963Written as TMP/SMX
- Effect of Nanotechnology Structured Water Magnalife for the Prevention of Recurrent Urinary Tract Infections.CompletedNot applicableUniversity of SulaimaniNCT04306731Written as Trimethoprim
Codes
What other systems call Trimethoprim · ClinicalTrials.gg INT008363
- MeSH (NLM) D014295TrimethoprimConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) AN164J8Y0XTRIMETHOPRIMConfirmed FDA, NLM, Wikidata
- RxNorm 10829Confirmed FDA, Wikidata
- Wikidata Q422665trimethoprimConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C908TrimethoprimOne source FDA
- DrugBank DB00440One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014295 | Trimethoprim | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | AN164J8Y0X | TRIMETHOPRIM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10829 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422665 | trimethoprim | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C908 | Trimethoprim | One source FDA |
| DrugBank | DB00440 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.