Drug

Leucovorin clinical trials

Also written Folinic acid, Wellcovorin, Lederfolin and NSC-3590.

studies test it: 351
open now: 60
in phase 3: 65
first study started: 1992

Keep track of what changes. Save the Leucovorin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

Watch these studies

How studies write it

Studies that test it under each name

Studies by the year they started

347 studies that test it; most in 2018 (23); 1 more planned to start later

Studies that test Leucovorin, by start year
Year	Studies
1992	2
1993	2
1994	5
1995	2
1996	4
1997	4
1998	2
1999	5
2000	8
2001	4
2002	10
2003	11
2004	12
2005	11
2006	16
2007	6
2008	3
2009	16
2010	11
2011	18
2012	16
2013	8
2014	10
2015	13
2016	10
2017	18
2018	23
2019	15
2020	15
2021	12
2022	7
2023	11
2024	12
2025	14
2026	11

By phase

A phase 1/2 study counts in both.

Early Phase 1: 1
Phase 1: 86
Phase 2: 237
Phase 3: 65
Phase 4: 5
No phase: 9

What it is tested for

Each study’s main condition, where its own words name it.

Colorectal Neoplasms: 55
Pancreatic Neoplasms: 34
Adenocarcinoma: 31
Stomach Neoplasms: 28
Neoplasms: 18
Rectal Neoplasms: 16
Biliary Tract Neoplasms: 11
Precursor Cell Lymphoblastic Leukemia-Lymphoma: 9
Colonic Neoplasms: 9
Lymphoma: 8
Carcinoma, Hepatocellular: 7
Carcinoma: 4

Who runs them

Industry 65 · Other 286

ImmunityBio, Inc. (18) · National Cancer Institute (NCI) (13) · M.D. Anderson Cancer Center (11) · National Health Research Institutes, Taiwan (10) · Children's Oncology Group (9) · Fujian Cancer Hospital (8) · University of Miami (7) · SWOG Cancer Research Network (6)

Often tested with

Tested in the same studies.

Fluorouracil (263) · Oxaliplatin (176) · Irinotecan (79) · Capecitabine (50) · Paclitaxel (47) · Bevacizumab (44) · Docetaxel (43) · Cisplatin (40)

Studies

Open first, then newest update. How each study uses Leucovorin is read from its arms, and is right about nine times in ten.

Testing it · 351

See all 351 studies that test Leucovorin →

Given in every arm · 539 — Leucovorin is usual care beside what is tested

Showing 20 of 539.

As the comparator · 49 — what is tested is compared with Leucovorin

Showing 20 of 49.

Codes

What other systems call Leucovorin · ClinicalTrials.gg INT007224

MeSH (NLM) D002955LeucovorinConfirmed ClinicalTrials.gov, NLM
UNII (FDA) Q573I9DVLPLEUCOVORINConfirmed FDA, NLM
RxNorm 6313One source FDA
NCI Thesaurus C71631LeucovorinOne source FDA

System	Code	Name there	Checked by
MeSH (NLM)	D002955	Leucovorin	Confirmed ClinicalTrials.gov, NLM
UNII (FDA)	Q573I9DVLP	LEUCOVORIN	Confirmed FDA, NLM
RxNorm	6313	—	One source FDA
NCI Thesaurus	C71631	Leucovorin	One source FDA

Also registered as leucovorin calcium (UNII RPR1R4C0P4 · RxNorm 225852) and leucovorin calcium pentahydrate (UNII R3W57OBQ5W).

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.

Leucovorin clinical trials

How studies write it

Name

Brand

Development codes

Other names

Combined with it in one product