Pneumonia clinical trials
The registry lists 1,564 studies for Pneumonia across more than 10 countries. 265 are recruiting or about to start. 658 of them are mainly about Pneumonia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 12 narrower conditions too, such as COVID-19: 10,607 studies, 1,057 open.
ClinicalTrials.gov finds 11,391 studies for Pneumonia. How that becomes 1,564 here
This page counts the studies the registry files under Pneumonia, and those it files under no condition that list Pneumoniathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 11,391Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −8,722Filed under a narrower condition, counted on its own pageCOVID-19 7,363 · Post-Acute COVID-19 Syndrome 396 · Pneumonia, Ventilator-Associated 349 · Community-Acquired Pneumonia 220 · Pneumonia, Pneumocystis 96 · Pneumonia, Bacterial 71 · 5 more
- −143List Pneumonia as a condition, but the registry did not file them under itMost often written as “Covid-19 Pneumonia” (22), “Non-Tuberculous Mycobacterial Pneumonia” (11), and “Interstitial Pneumonia” (8). The registry filed 2 of them under no condition at all, and the others under other conditions only, most often Lung Diseases, Interstitial (29) and Idiopathic Pulmonary Fibrosis (22).
- −962Match it another way170 name it in the title, 37 in a keyword, and 755 by a synonym or other text the search reads.
- 1,564The count on this page173 of them list Pneumonia in their own words; the registry filed them under no condition.
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Who runs them
Assistance Publique - Hôpitaux de Paris (23) · Pfizer (21) · Assiut University (18) · Cairo University (13) · International Centre for Diarrhoeal Disease Research, Bangladesh (13) · GlaxoSmithKline (13) · National Institute of Allergy and Infectious Diseases (NIAID) (13) · Bayer (11)
What is being tested here
Drugs under test in Pneumonia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Baricitinib | 3 | 3 | 5 |
| Hydroxychloroquine | 2 | 6 | 9 |
| Remdesivir | 2 | 3 | 5 |
| Interleukin 1 Receptor Antagonist Protein | 2 | 4 | 5 |
| Tocilizumab | 2 | 2 | 5 |
| Aspirin | 2 | 3 | 4 |
| Ascorbic Acid | 2 | 1 | 4 |
| Nigella sativa oil | 2 | 0 | 2 |
| Baloxavir | 2 | 2 | 2 |
| Ibuzatrelvir | 2 | 2 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 3 open · JAK inhibitors 3 open · Corticosteroids 2 open · NSAIDs 2 open · Bronchodilators 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Pirfenidone Capsules in the Treatment of Radiation-induced Lung Injury With or Without Immune Pneumonia · Phase 3 · Beijing Continent Pharmaceutical Co, Ltd.
- Mar 2027A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age · Phase 3 · Vaxcyte, Inc.
- Mar 2027Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Prior Pneumococcal Vaccination · Phase 3 · Vaxcyte, Inc.
- Apr 2027A Study of COVID-19 Vaccine(s) in Children and Adults · Phase 3 · BioNTech SE
- Sep 2027A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Oct 2027A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- Nov 2026AI-Assisted Bronchoscopy Navigation and Diagnostic System for Severe Pneumonia: A Multicenter Prospective Study · Chinese Medical Association
- Nov 2026Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
- Nov 2026Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU · Brigham and Women's Hospital
- Nov 2026Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases · Assiut University
Who these studies take
Of the 158 Pneumonia studies recruiting now, 84 (53%) set no upper age limit and 47 (30%) stop at 75 or younger. 41 (26%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 24 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 24 (15%) | 24 (15%) |
| 18 | 120 (76%) | 120 (76%) |
| 30 | 118 (75%) | 118 (75%) |
| 40 | 121 (77%) | 121 (77%) |
| 50 | 121 (77%) | 121 (77%) |
| 65 | 124 (78%) | 124 (78%) |
| 75 | 117 (74%) | 117 (74%) |
| 85 | 104 (66%) | 104 (66%) |
Across all 1,564 studies, recruiting or not: 28% stop at 75 or younger and 25% at 65; 29% take children; 1% are for women only and <1% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pneumonia studies take
Of 67 phase 3 interventional studies under Pneumonia, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 12 mo6–34 · 35 studies | — | — |
| Phase 2 | 14 mo7–28 · 64 studies | — | 11 mo6–28 · 39 studies |
| Phase 3 | 19 mo8–41 · 67 studies | — | 26 mo9–57 · 41 studies |
| Phase 4 | 31 mo21–40 · 49 studies | — | 33 mo21–43 · 42 studies |
| Interventional, no phase | 21 mo10–31 · 265 studies | — | 21 mo11–31 · 258 studies |
| Observational | 27 mo13–53 · 223 studies | — | 27 mo14–57 · 210 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
Results posted1
Newly registered11
- A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation TrialNov 6, 2026NCT07922226
- Effect of Nurse-Directed Therapeutic Positioning in Children With PneumoniaNov 3, 2026NCT07913191
- Respiratory Physiotherapy and Inflammatory Biomarkers in Critically Ill Patients With PneumoniaNov 2, 2026NCT07909616
- The Effects of Wintergreen Essential Oil Inhalation on Alleviating Dyspnea Among Patients With PneumoniaOct 26, 2026NCT07894835
- A Multicenter Randomized Trial of CT-Based AI Decision Support for Early Pneumonia CareOct 26, 2026NCT07895290
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- Modified Inhaled Nitric Oxide in Ventilated Patients With Acute Respiratory FailureOct 23, 2026NCT07892001
- Pulmonary-Specific Enteral Nutrition in Mechanically Ventilated Patients With PneumoniaOct 23, 2026NCT07892521
- Effects of Lumbrokinase DLBS1033 on D-Dimer, Interleukin-6, and Clinical Outcomes in Patients With Pneumonia and SepsisOct 23, 2026NCT07892794
- Neutrophil Monocyte Lymphocyte Ratios in Pediatric Chest InfectionsOct 22, 2026NCT07888049
- Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory InfectionOct 20, 2026NCT07883902
- Chest Radiography Versus Ultra-Low-Dose Chest Computed Tomography in Adults in the Emergency DepartmentOct 13, 2026NCT07870525
Studies
Recruiting first, then most recently updated. Showing 50 of 1,564. Browse all 1,564 → or search them.
- The LalelaLung Study: Digital Stethoscope Clinical EvaluationNot yet recruitingNCT07631377Phase 4
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-ConsultsRecruitingNCT07507435Not applicable1 country
- Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)RecruitingNCT000061501 country
- Personalized Ventilator Settings for Patients on ECMOEnrolling by invitationNCT07673250Not applicable1 country
- A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation TrialNot yet recruitingNCT07922226Phase 2/3
- Expanded Diagnostic Strategy in Older Adults Hospitalized With Community-Acquired Acute Respiratory InfectionNot yet recruitingNCT07883902Not applicable1 country
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 329 countries
- Effect of Nurse-Directed Therapeutic Positioning in Children With PneumoniaNot yet recruitingNCT07913191Not applicable
- Respiratory Physiotherapy and Inflammatory Biomarkers in Critically Ill Patients With PneumoniaRecruitingNCT079096161 country
- Detection and Characterization of Lower Respiratory Infections in Critically Ill PatientsRecruitingNCT010689901 country
- Pneumonia and Pleuropneumonia in Hospitalized ChildrenRecruitingNCT052746071 country
- Modified Inhaled Nitric Oxide in Ventilated Patients With Acute Respiratory FailureNot yet recruitingNCT07892001Not applicable1 country
- The Effects of Wintergreen Essential Oil Inhalation on Alleviating Dyspnea Among Patients With PneumoniaRecruitingNCT07894835Not applicable1 country
- A Multicenter Randomized Trial of CT-Based AI Decision Support for Early Pneumonia CareRecruitingNCT07895290Not applicable1 country
- Neutrophil Monocyte Lymphocyte Ratios in Pediatric Chest InfectionsNot yet recruitingNCT07888049
- Prevention of COVID-19 Infection to Severe Pneumonia or ARDSNot yet recruitingNCT04569227Phase 21 country
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe DiseaseRecruitingNCT06679140Phase 319 countries
- Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P TrialNot yet recruitingNCT07308483Not applicable1 country
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely ImmunocompromisedRecruitingNCT07013474Phase 318 countries
- Study of Lung Proteins in Patients With PneumoniaRecruitingNCT000779091 country
- Chest Radiography Versus Ultra-Low-Dose Chest Computed Tomography in Adults in the Emergency DepartmentRecruitingNCT078705251 country
- Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated PneumoniaNot yet recruitingNCT06488794Phase 2/3
- Immune Responses and Pulmonary Complications After Cardiac Surgery With Cardiopulmonary BypassNot yet recruitingNCT078655331 country
- Opportunistic Pneumococcal Immunisation Trial in MALnutritionRecruitingNCT06817421Phase 41 country
- Study of Hospitalised Patients With Acute Respiratory ConditionsRecruitingNCT050950901 country
- Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAPRecruitingNCT06670833Not applicable3 countries
- Quality of Life After Lower Respiratory Tract InfectionNot yet recruitingNCT078079171 country
- AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired PneumoniaRecruitingNCT05848713Phase 34 countries
- A Study of COVID-19 Vaccine(s) in Children and AdultsRecruitingNCT07798648Phase 31 country
- Optimising Antibiotic Use for Paediatric Lower Respiratory Tract Infections in AfricaRecruitingNCT07841691Not applicable1 country
- Aspirin in Acute Pneumonia in the Elderly: a Multicenter, Double-blind, Randomized, Placebo-controlled Trial.Not yet recruitingNCT06774846Phase 3
- Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary DiseasesRecruitingNCT069833661 country
- Effectiveness of Chatbot for Improving Caregiving Outcomes in Primary Caregivers of Geriatric Pneumonia Patients: A Study on Knowledge, Attitude and Practice.RecruitingNCT07463443Not applicable1 country
- Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.RecruitingNCT07432191Not applicable1 country
- Urine Pneumococcal Antigen ProjectRecruitingNCT071812001 country
- Oral Hygiene Assistance Training ProgramNot yet recruitingNCT07807397Phase 4
- The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, and Lung MechanicsRecruitingNCT07188038Not applicable1 country
- Assessing Role of Probiotics in Children Aged 6-36 Months Treated for PneumoniaNot yet recruitingNCT07399717Not applicable1 country
- Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary ImpairmentRecruitingNCT050411401 country
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT042784042 countries
- Effects of Buteyko Breathing Versus Incentive Spirometry on Oxygen Saturation, Dyspnoea, Exercise Tolerance, and Sputum Clearance in Patients With Smog Induced PneumoniaRecruitingNCT07759583Not applicable1 country
- Efficacy and Safety of Intrapulmonary Percussive Ventilation in Patients With Pulmonary Infection Receiving Invasive Mechanical VentilationRecruitingNCT07453966Not applicable1 country
- How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.RecruitingNCT06495021Not applicable1 country
- A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of AgeRecruitingNCT07730450Phase 41 country
- Inhaled Budesonide for REcurrence Prevention and Adjuvant THerapy in Checkpoint Inhibitor PneumonitisRecruitingNCT06860542Phase 21 country
- Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BALRecruitingNCT06134492Phase 31 country
- Preadmission GLP-1 Receptor Agonist Plus SGLT2 Inhibitor Use and Early Outcomes After Pneumonia Hospitalization in Adults With Type 2 DiabetesNot yet recruitingNCT077086101 country
- Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and AdolescentsRecruitingNCT062014941 country
- TMP-SMX for Non-HIV PCP: A Prospective Multicenter StudyNot yet recruitingNCT07690410
- Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected PneumoniaNot yet recruitingNCT07703852