Pneumonia, Pneumocystis clinical trials
The registry lists 108 studies for Pneumonia, Pneumocystis across more than 10 countries. 16 are recruiting or about to start. 90 of them are mainly about Pneumonia, Pneumocystis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (36) · Fisons (5) · U.S. Bioscience (5) · Glaxo Wellcome (4) · McGill University Health Centre/Research Institute of the McGill University Health Centre (3) · Shanghai Public Health Clinical Center (2) · Peking Union Medical College Hospital (2) · University of Pittsburgh (2)
What is being tested here
Drugs under test in Pneumonia, Pneumocystis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Jun 2027Corticosteroids for PJP in Non-HIV Immunocompromised Adults · Phase 3 · Qingyuan Zhan
- Dec 2026CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia · University Hospital, Tours
- Dec 2026Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii · University Hospital, Brest
- Jul 2027Optimizing the Diagnosis of Pneumocystis in Immunocompromised Patients · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 9 Pneumonia, Pneumocystis studies recruiting now, 6 (67%) set no upper age limit and 1 (11%) stop at 75 or younger. 1 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (11%) | 1 (11%) |
| 18 | 9 (100%) | 9 (100%) |
| 30 | 9 (100%) | 9 (100%) |
| 40 | 9 (100%) | 9 (100%) |
| 50 | 9 (100%) | 9 (100%) |
| 65 | 8 (89%) | 8 (89%) |
| 75 | 8 (89%) | 8 (89%) |
| 85 | 8 (89%) | 8 (89%) |
Across all 108 studies, recruiting or not: 19% stop at 75 or younger and 16% at 65; 50% take children; 0% are for women only and 1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Echinocandin Added to Standard Treatment for Severe Pneumocystis PneumoniaOct 28, 2026NCT07900373
Studies
Recruiting first, then most recently updated. Showing 50 of 108. Browse all 108 → or search them.
- Echinocandin Added to Standard Treatment for Severe Pneumocystis PneumoniaNot yet recruitingNCT07900373Phase 31 country
- CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis PneumoniaRecruitingNCT06892951Phase 1/21 country
- Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor ScoreRecruitingNCT076815831 country
- Low- vs Standard-Dose TMP-SMX for Prevention of Pneumocystis Pneumonia After Kidney TransplantationNot yet recruitingNCT07619027Phase 4
- Optimizing the Diagnosis of Pneumocystis in Immunocompromised PatientsRecruitingNCT068900781 country
- Short-term Steroid Therapy in Patients With P. Jirovecii Pneumonia Due to HIV / AIDSEnrolling by invitationNCT03856229Not applicable1 country
- Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii PneumoniaRecruitingNCT04851015Phase 31 country
- Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)Not yet recruitingNCT07357103Phase 4
- How Long Should we Give Steroids for Patients With Severe PCPNot yet recruitingNCT07328984Phase 41 country
- Introduction of Polymerase Chain Reaction (PCR) in Microbiology and ParasitologyRecruitingNCT072693141 country
- Corticosteroids for PJP in Non-HIV Immunocompromised AdultsNot yet recruitingNCT07152613Phase 3
- Pneumocystis Jirovecii GenotypingNot yet recruitingNCT06442345
- Rezafungin for Treatment of Pneumocystis Pneumonia in HIV AdultsRecruitingNCT05835479Phase 21 country
- Caspofungin for Pneumocystis Pneumonia in PLWHIV.RecruitingNCT066913211 country
- Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic DiseaseRecruitingNCT06499233Phase 41 country
- Factors Associated With Survival in Patients Having Pneumocystis JiroveciiRecruitingNCT061734531 country
- New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis PneumoniaCompletedNCT003425891 country
- Pneumocystis Pneumonia Diagnosis in HIV- PatientsCompletedNCT02648256Not applicable1 country
- Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow TransplantationCompletedNCT04368559Phase 39 countries
- Performance Evaluation of the Fujifilm Wako Beta-D-glucan Technique in the Diagnosis of Major Invasive Fungal Infections (IFI)CompletedNCT072729151 country
- Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating CenterCompletedNCT008708571 country
- Pneumocystis in Patients Over 75 YearCompletedNCT070041271 country
- Prospective Observational Study on the Incidence of Opportunistic Fungal InfectionsCompletedNCT057071561 country
- Assessing Diagnostic Methods for Invasive Fungal Disease in Lung Transplant RecipientsCompletedNCT06654076
- Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis JiroveciiActive, not recruitingNCT064319581 country
- Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath CondensateCompletedNCT043584191 country
- Pneumocystis Jirovecii Pneumonia in Non-HIV-infected Immunocompromised PatientsCompletedNCT054587521 country
- A Case-control Study on Risk Factors, Timing, and PCR Use, for Pneumocystis Pneumonia (PcP) After Allogeneic HSCTCompletedNCT050771506 countries
- Non Invasive Diagnosis of Pneumocystis PneumoniaCompletedNCT03613025Not applicable1 country
- Radiomics Model for the Diagnosis of Pneumocystis Jirovecii Pneumonia in Non-HIV PatientsStatus unknownNCT057016311 country
- PCP in Immunocompromised Population in Southern ChinaStatus unknownNCT056051451 country
- Specialized Proresolving Mediators in Pneumocystis Jirovecii PneumoniaCompletedNCT03606252Not applicable1 country
- Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS PatientsStatus unknownNCT051530051 country
- A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected PatientsCompletedNCT00000991Phase 32 countries
- A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCPCompletedNCT00000998Phase 11 country
- A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive ChildrenCompletedNCT00000811Phase 22 countries
- A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or SulfonamidesCompletedNCT00000802Phase 32 countries
- A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCPCompletedNCT00000700Phase 31 country
- Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedNCT00001014Phase 31 country
- A Study of Pentamidine in the Prevention of Pneumocystis Carinii PneumoniaCompletedNCT00001003Not applicable1 country
- Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedNCT00001013Phase 31 country
- Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia ProphylaxisCompletedNCT00000816Phase 43 countries
- Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV InfectionCompletedNCT00000739Phase 12 countries
- The Safety and Effectiveness of Methylprednisolone in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Children With AIDSWithdrawnNCT00000741Phase 31 country
- Escalating Multiple-Dose Safety and Tolerance of WR 6026 Hydrochloride in HIV-Infected SubjectsCompletedNCT00000740Phase 11 country
- A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected PatientsCompletedNCT00000748Phase 31 country
- Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and ZidovudineCompletedNCT00000732Not applicable1 country
- Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine TherapyCompletedNCT00000722Not applicable1 country
- A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDSCompletedNCT00000640Phase 31 country
- A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)CompletedNCT00000727Phase 31 country