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CompletedNCT04306731Updated Mar 17, 2020

Effect of Nanotechnology Structured Water Magnalife for the Prevention of Recurrent Urinary Tract Infections.

An interventional study of Nanotechnology Structured water Magnalife and Trimethoprim in Recurrent Urinary Tract Infection, sponsored by University of Sulaimani. Completed at 1 site in Iraq. Open to female participants aged 24 Years to 80 Years. Per ClinicalTrials.gov, last updated 2020-03-17.

Sponsored by University of Sulaimani · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 5 years 5 months after the study started (first participant enrolled Sep 2014, registered Mar 2020).
Phase
Not applicable
Study type
Interventional
Enrollment
437
Allocation
Randomized
Ages
24 Years to 80 Years
Sex
Female
01

Study summary

This study investigates nanotechnology structured water magnalife in urology and to test its effects against lower urinary tract infections (UTI) in females.

Read the detailed description

This study represents the first time to use nanotechnology structured water magnalife in urology and to test its effects against lower urinary tract infections (UTI) in females. Urinary tract infection (UTI ) is the second most common bacterial infection, affecting women at a much higher frequency than men. There is a higher rate of recurrence of UTI, and a recurrent infection will follow 25-35% of initial UTI episodes within 3-6 months.

Intermittent or prolonged low dose antibiotic therapy has been used to treat and prevent recurrent UTI. Emerging of resistance to antimicrobial agents, enormous economic burden, and the side effects of antibiotics have led to the search for an alternative non-antibiotic prophylaxis of recurrent UTI. Nanotechnology structured water is a new type of drinking water that has been prepared using different types of energy fields and electromagnetic fields to produce this structured water, which has new and different characteristics from the ordinary water.

In the current study, the efficacy of nanotechnology structured water magnalife was compared with low-dose Trimethoprim and bottled drinking water for the prevention of recurrent UTI.

02

Conditions studied

  • Recurrent Urinary Tract Infection

Keywords

  • nanotechnology water, antibiotic prophylaxis, recurrent UTI.
03

In context

Infections

6,686 studies on the registry are indexed under Infections; 807 are open to participants now.

This study's enrollment of 437 is above the median of 120 across 4,199 interventional studies indexed under Infections.

Browse Infections studies →

Lead sponsor

University of Sulaimani is the lead sponsor of 16 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
24 Years to 80 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • ≥ 2 (two or more than two) UTI in the last 6 months
  • ≥ 3 (three or more than three) UTI in the last 12 months

Exclusion criteria

Exclusion Criteria:

  • immunotherapy
  • radiotherapy
  • malignancy
  • steroids
  • chronic infections
  • chemotherapy
  • immunosuppressive drugs
  • anatomical abnormality of the urinary tract
  • surgical operation the urinary tract
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
437 participants (actual)

Study arms

  • Experimental
    Interventional (Group M)

    The group of patients given nanotechnology structured water magnalife

    Dietary Supplement: Nanotechnology Structured water Magnalife

  • Active comparator
    Control (Group T)

    The group of patients given Trimethoprim

    Drug: Trimethoprim

  • Placebo comparator
    Placebo (Group O)

    The group of patients given ordinary bottled drinking water

    Dietary Supplement: Ordinary bottled drinking water

Interventions

  • Dietary supplementNanotechnology Structured water Magnalife

    Nanotechnology Structured water Magnalife is drinking water that has been modified using nanotechnology to change the structuring of water molecules

    Also known as: Magnalife, 5200250040466

  • DrugTrimethoprim

    Antibiotic

    Also known as: Proloprim

  • Dietary supplementOrdinary bottled drinking water

    Placebo

06

What researchers measure

Primary outcomes

  1. Recurrent Urinary Tract Infection

    Urinalysis by GUE (\>10 white blood cells (WBC)/mm3 per high-power field (HPF) Urine culture (urinary pathogen of ≥105 colony-forming units (CFU) per mL)

    Time frame: Twelve months

Secondary outcomes

  1. Time to first recurrent UTI

    The time since the beginning of the study until the first recurrent UTI (days)

    Time frame: Twelve months

07

Study locations

1 site
  • College of Medicine, University of Sulaimani
    Sulaymaniyah, Kurdistan Region 00964, Iraq
08

References and documents

Individual participant data

Plan to share: No — The duration of illness, number of recurrence of UTI, other co-morbid diseases

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 17, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04306731
Lead sponsor
University of Sulaimani
Responsible party
ALI KAMAL M. SAMI (Principal investigator, University of Sulaimani) — Principal investigator
First posted
Mar 13, 2020
Start date
Sep 20, 2014
Primary completion
Apr 21, 2017
Completion
Apr 21, 2017
Last update
Mar 17, 2020

Study contacts

Ali K M.Sami, Ph.D.
principal investigator · College of Medicine, University of Sulaimani

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.

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