Drug
Eszopiclone clinical trials
Also written Lunesta and SEP-190.
- studies test it
- 62
- open now
- 5
- in phase 3
- 15
- first study started
- 2001
Keep track of what changes. Save the Eszopiclone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
62 studies that test it; most in 2006 (12)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2003 | 2 |
| 2004 | 4 |
| 2005 | 5 |
| 2006 | 12 |
| 2007 | 7 |
| 2008 | 10 |
| 2009 | 4 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 3 |
| 2015 | 1 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 3 |
| 2024 | 1 |
| 2025 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 8
- Phase 2
- 8
- Phase 3
- 15
- Phase 4
- 24
- No phase
- 8
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 22 · Other 40
Sumitomo Pharma America, Inc. (14) · University of California, San Diego (4) · Brigham and Women's Hospital (4) · Massachusetts General Hospital (4) · Yale University (3) · Eisai Co., Ltd. (3) · VA Office of Research and Development (2) · Johns Hopkins University (2)
Often tested with
Tested in the same studies.
Trazodone (2) · Acetazolamide (2) · Venlafaxine (1) · Ramelteon (1) · Zolpidem (1) · Lemborexant (1) · Atomoxetine (1) · Escitalopram (1)
Studies
Open first, then newest update. How each study uses Eszopiclone is read from its arms, and is right about nine times in ten.
Testing it · 62
- Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty SleepingRecruitingPhase 2Flinders UniversityNCT06928766Written as Eszopiclone 3 mg
- Rescue Pharmacotherapy for OSARecruitingPhase 1/2Brigham and Women's HospitalNCT05293600Written as Atomoxetine and eszopiclone
- Endotypic Traits and Obstructive Sleep Apnea SurgeryRecruitingPhase 2University of California, Los AngelesNCT05953610Written as Eszopiclone 3 mg QHS
- Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep ApneaRecruitingPhase 3Yale UniversityNCT07332442Written as Eszopiclone
- Impact of Eszopiclone on Blood Pressure in Patients With Insomnia and Hypertension (PRYSMA-HTN)RecruitingPhase 4University of Sao PauloNCT07018557Written as Eszopiclone 3 mg
- National Adaptive Trial for PTSD Related InsomniaCompletedPhase 3VA Office of Research and DevelopmentNCT03668041Written as Eszopiclone
- Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISACompletedPhase 4University of Sao Paulo General HospitalNCT06017921Written as Eszopiclone 3 mg
- Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)CompletedPhase 2University of California, San DiegoNCT05951023Written as Eszopiclone 2 mg
- Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSDCompletedPhase 4VA Office of Research and DevelopmentNCT03937713Written as eszopiclone
- Combination Drug-Therapy for Patients With Untreated Obstructive Sleep ApneaCompletedPhase 2University of California, San DiegoNCT04639193Written as Eszopiclone
- Safety and Efficacy of Chronic Hypnotic Use 2CompletedPhase 4Henry Ford Health SystemNCT02456532Written as Eszopiclone
- Treatment of Insomnia in MigraineursCompletedPhase 4MedVadis Research CorporationNCT00812214Written as eszopiclone
- Eszopiclone for the Treatment of Posttraumatic Stress DisorderCompletedPhase 4Rush University Medical CenterNCT01605253Written as Eszopiclone
- Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and ZybanTerminatedPhase 4Yale UniversityNCT00511134Written as Eszopiclone
- Bioavailability of Eszopiclone 3.0 mg With Regards to Reference ProductCompletedPhase 1Laboratorios Andromaco S.A.NCT05349396Written as Eszopiclone 3mg Test Drug T-1 Coated Tablets
- Eszopiclone in the Treatment of Insomnia and FibromyalgiaCompletedPhase 4Lesley A. Allen, Ph.D.NCT00392041Written as Eszopiclone
- Sleep Effectiveness and Insulin and Glucose HomeostasisTerminatedPhase 1Beth Israel Deaconess Medical CenterNCT01887691Written as eszopiclone
- Insomnia and Osteoarthritis StudyCompletedNot applicableJohns Hopkins UniversityNCT00374556Written as Eszopiclone
- Improving Sleep and Psychological Functioning in People With Depression and InsomniaCompletedPhase 4Wake Forest University Health SciencesNCT00247624Written as Eszopiclone
- Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated InsomniaCompletedPhase 3Sumitomo Pharma America, Inc.NCT00857220Written as eszopiclone
See all 62 studies that test Eszopiclone →
Given in every arm · 2 — Eszopiclone is usual care beside what is tested
As the comparator · 3 — what is tested is compared with Eszopiclone
- Modified Suanzaoren Decoction Versus Eszopiclone for the Treatment of Chronic Insomnia DisorderCompletedNot applicableCentral South UniversityNCT06452953Written as Eszopiclone 1 mg
- Hypnotics to Improve Polysomnography Yield: Eszopiclone vs Ramelteon?CompletedNot applicableSouthern California Institute for Research and EducationNCT00811746Written as Lunesta (Eszopiclone)
- Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot StudyCompletedPhase 2/3University of MinnesotaNCT00515177Written as eszopiclone
Codes
What other systems call Eszopiclone · ClinicalTrials.gg INT006614
- MeSH (NLM) D000069582EszopicloneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) UZX80K71OEESZOPICLONEConfirmed FDA, NLM, Wikidata
- RxNorm 461016Confirmed FDA, Wikidata
- Wikidata Q413184eszopicloneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C65545EszopicloneOne source FDA
- DrugBank DB00402One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069582 | Eszopiclone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | UZX80K71OE | ESZOPICLONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 461016 | — | Confirmed FDA, Wikidata |
| Wikidata | Q413184 | eszopiclone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C65545 | Eszopiclone | One source FDA |
| DrugBank | DB00402 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.