Acquired Immunodeficiency Syndrome clinical trials
The registry lists 3,035 studies for Acquired Immunodeficiency Syndrome across more than 10 countries. 306 are recruiting or about to start. 1,528 of them are mainly about Acquired Immunodeficiency Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 10,212 studies for Acquired Immunodeficiency Syndrome. How that becomes 3,033 here
This page counts the studies the registry files under Acquired Immunodeficiency Syndrome, and those it files under no condition that list Acquired Immunodeficiency Syndromethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 10,212Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −73List Acquired Immunodeficiency Syndrome as a condition, but the registry did not file them under itMost often written as “AIDS Dementia Complex” (8), “AIDS-related Diffuse Large Cell Lymphoma” (8), and “AIDS-related Small Noncleaved Cell Lymphoma” (8). The registry filed 16 of them under no condition at all, and the others under other conditions only, most often HIV Infections (33) and AIDS Dementia Complex (10).
- −7,106Match it another way186 name it in the title, 202 in a keyword, and 6,718 by a synonym or other text the search reads.
- 3,033The count on this page
Get an email when these change. Save the Acquired Immunodeficiency Syndrome studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Status
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (311) · ViiV Healthcare (150) · University of California, San Francisco (77) · Columbia University (49) · Johns Hopkins University (41) · University of North Carolina, Chapel Hill (39) · Massachusetts General Hospital (38) · Emory University (38)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Optimizing Tobacco Use Treatment for PLWHA · Phase 3 · Abramson Cancer Center at Penn Medicine
- Jan 2027Cefixime Clinical Trial · Phase 3 · University of Southern California
- Jul 2027A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011) · Phase 3 · Merck Sharp & Dohme LLC
- Oct 2027A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010) · Phase 3 · Merck Sharp & Dohme LLC
- Nov 2026IGHID 12230 - An Implementation Trial of an Experiential Brief Alcohol Intervention for HIV Prevention · University of North Carolina, Chapel Hill
- Nov 2026Cross-disciplinary HIV Integrated Mental Health Support Intervention · Emory University
- Nov 2026A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of HIV/AIDS Complicated With Infection · Zhejiang University
- Nov 2026BRAZILIAN REGISTRY OF CHRONIC NON-COMMUNICABLE DISEASES IN PEOPLE LIVING WITH HIV/AIDS · Hospital Alemão Oswaldo Cruz
- Nov 2026Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors · Tulane University
- Nov 2026WiseApp for Spanish Speakers Living With HIV · Columbia University
Who these studies take
Of the 198 Acquired Immunodeficiency Syndrome studies recruiting now, 118 (60%) set no upper age limit and 67 (34%) stop at 75 or younger. 43 (22%) take children under 18. 23 (12%) are for women only and 12 (6%) for men only; 68 (34%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 18 (9%) | 15 (8%) |
| 18 | 159 (80%) | 156 (79%) |
| 30 | 164 (83%) | 150 (76%) |
| 40 | 164 (83%) | 152 (77%) |
| 50 | 165 (83%) | 159 (80%) |
| 65 | 146 (74%) | 141 (71%) |
| 75 | 128 (65%) | 123 (62%) |
| 85 | 122 (62%) | 117 (59%) |
Across all 3,035 studies, recruiting or not: 36% stop at 75 or younger and 32% at 65; 26% take children; 8% are for women only and 7% for men only; 28% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Acquired Immunodeficiency Syndrome studies take
Of 139 phase 1 interventional studies under Acquired Immunodeficiency Syndrome, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 14 mo4–28 · 139 studies | 5 mo2–18 · 76 studies | 23 mo15–39 · 63 studies |
| Phase 1/2 | 42 mo24–… · 29 studies | — | — |
| Phase 2 | 36 mo18–71 · 86 studies | 23 mo14–71 · 29 studies | 47 mo22–65 · 57 studies |
| Phase 3 | 26 mo19–34 · 65 studies | 22 mo17–27 · 34 studies | 34 mo20–51 · 31 studies |
| Phase 4 | 31 mo22–47 · 70 studies | — | 32 mo23–49 · 64 studies |
| Interventional, no phase | 29 mo17–45 · 648 studies | — | 30 mo17–45 · 642 studies |
| Observational | 44 mo19–79 · 177 studies | — | 46 mo22–83 · 165 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting7
- C2001P-CS3: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVNov 12, 2026NCT07576842
- Psilocybin Therapy for Methamphetamine Use Disorder and HIVNov 9, 2026NCT07756736
- Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75Oct 29, 2026NCT07388394
- Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 KenyaOct 20, 2026NCT07468695
- Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South AfricaOct 20, 2026NCT07645378
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- Feasibility Study Comparing One vs Two Probes for TA Among Cervical Cancer Screen Positive WLWH in C1001P-CS5 RwandaOct 19, 2026NCT07390916
- Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 ZimbabweOct 19, 2026NCT07645352
Results posted7
- High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consultsNov 10, 2026NCT03856879
- The OPENS Trial: Offering Women PrEP (Aim 2)Nov 4, 2026NCT05619497
- A Peer-Led Intervention to Improve Postpartum Retention in HIV CareNov 3, 2026NCT04168008
- A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)Oct 28, 2026NCT03896776
- Observational Study of People Living With HIV Treated With CD19-directed CAR T CellOct 28, 2026NCT05784415
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- HPV Vaccination in HIV Infected and HIV Uninfected Adolescents in EswatiniOct 27, 2026NCT04982614
- Impact of Metformin on Immuno-virologic Parameters in HIVOct 20, 2026NCT04500678
Stopped4
- Observational Study for the Evaluation of the Role of HIV-1 Tat Protein and Anti-Tat Immune Response In HIV ReservoirTerminatedNov 9, 2026NCT04263207
- Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2TerminatedNov 6, 2026NCT06006143
- Impact of Metformin on Immuno-virologic Parameters in HIVTerminatedOct 20, 2026NCT04500678
- A Study to Assess the Safety and Pharmacokinetics of a Human Monoclonal Antibody (VH4527079) in Healthy Adults and Persons With HIVTerminatedOct 15, 2026NCT06652958
Newly registered8
- Decentralized, Status Neutral, Stakeholder-engaged, Post-incarceration Intervention for People Living With and at Risk for HIVNov 10, 2026NCT07927673
- C2001P-CS6: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVNov 9, 2026NCT07925307
- Cohort of Women Living With HIV-1 and Receiving Bictegravir/Emtricitabine/Tenofovir AlafenamideNov 6, 2026NCT07921472
- Multiple Interventions With Distinct Anti-reservoir Activities in People on Antiretroviral TreatmentOct 29, 2026NCT07903441
- Bwelela Easy StudyOct 28, 2026NCT07900750
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- Reducing Arterial Inflammation Using Eplerenone and Statins in HIVOct 23, 2026NCT07892664
- Testing a Multi-Level Approach to Reduce Stigma for Women Living With HIVOct 19, 2026NCT07881575
- A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir SizeOct 19, 2026NCT07881809
Studies
Recruiting first, then most recently updated. Showing 50 of 3,035. Browse all 3,035 → or search them.
- Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical CareRecruitingNCT06598397Phase 41 country
- C2001P-CS3: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVRecruitingNCT07576842Not applicable1 country
- A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir SizeNot yet recruitingNCT07881809Phase 21 country
- Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV InfectionRecruitingNCT007890091 country
- Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIVRecruitingNCT06001814Not applicable1 country
- Decentralized, Status Neutral, Stakeholder-engaged, Post-incarceration Intervention for People Living With and at Risk for HIVNot yet recruitingNCT07927673Not applicable1 country
- Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment InterruptionRecruitingNCT05419024Phase 21 country
- Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...RecruitingNCT05470491Phase 1/21 country
- Psilocybin Therapy for Methamphetamine Use Disorder and HIVRecruitingNCT07756736Phase 21 country
- Combating Related Epidemics in HCVNot yet recruitingNCT07560046Phase 4
- C2001P-CS6: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVRecruitingNCT07925307Not applicable1 country
- Promoting Aging and Thriving With HIVEnrolling by invitationNCT07192419Not applicable1 country
- Cohort of Women Living With HIV-1 and Receiving Bictegravir/Emtricitabine/Tenofovir AlafenamideRecruitingNCT079214721 country
- The Trans-Led Care StudyRecruitingNCT06880705Not applicable1 country
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)RecruitingNCT07266831Phase 2/39 countries
- Combating HIV Stigma in Healthcare Settings: A Standardized Patient ApproachNot yet recruitingNCT06975176Not applicable1 country
- Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 KenyaRecruitingNCT07468695Not applicable1 country
- Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 ZimbabweRecruitingNCT07645352Not applicable1 country
- Feasibility Study Comparing One vs Two Probes for TA Among Cervical Cancer Screen Positive WLWH in C1001P-CS5 RwandaRecruitingNCT07390916Not applicable1 country
- Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South AfricaRecruitingNCT07645378Not applicable1 country
- Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum WomenEnrolling by invitationNCT07064928Not applicable1 country
- PNF RCT to Decrease Alcohol Use and Increase HIV PreventionNot yet recruitingNCT07731932Not applicable1 country
- Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)RecruitingNCT017301311 country
- Multiple Interventions With Distinct Anti-reservoir Activities in People on Antiretroviral TreatmentRecruitingNCT07903441Phase 21 country
- Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75RecruitingNCT07388394Not applicable1 country
- ORCHID: An Online Intervention for Persons With HIV (Miami)Enrolling by invitationNCT05935644Not applicable1 country
- Bwelela Easy StudyNot yet recruitingNCT07900750Not applicable1 country
- Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)RecruitingNCT04375800Phase 28 countries
- Testing a Multi-Level Approach to Reduce Stigma for Women Living With HIVNot yet recruitingNCT07881575Not applicable1 country
- Assessing Pharmacy Technician Educational Training for the Provision of Over-the-Counter Hearing Aids in Rural Alabama and Mississippi PharmaciesRecruitingNCT06864273Not applicable1 country
- Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB TreatmentRecruitingNCT05671718Not applicable1 country
- Reducing Arterial Inflammation Using Eplerenone and Statins in HIVNot yet recruitingNCT07892664Phase 2/31 country
- Healer-initiated HIV Counseling and Testing Versus Standard of Care in Rural South AfricaRecruitingNCT06483854Not applicable1 country
- C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United StatesNot yet recruitingNCT075201881 country
- A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)RecruitingNCT07071623Phase 33 countries
- Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV CareRecruitingNCT06462807Not applicable1 country
- Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and CancerRecruitingNCT000065181 country
- Viral Load in Blood and Lymph Tissues in People Living With HIVRecruitingNCT000013161 country
- Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIVRecruitingNCT04902443Phase 11 country
- Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi SarcomaRecruitingNCT04941274Phase 1/21 country
- Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseRecruitingNCT033008301 country
- PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi SarcomaRecruitingNCT04303117Phase 1/21 country
- Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral TherapyRecruitingNCT06819176Phase 11 country
- Striving Towards EmPowerment and Medication Adherence R01RecruitingNCT06463886Not applicable1 country
- A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIVRecruitingNCT07698600Phase 12 countries
- SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral TherapyRecruitingNCT05586581Phase 1/21 country
- IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in TanzaniaNot yet recruitingNCT07459218Not applicable1 country
- Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in FloridaNot yet recruitingNCT06015581Not applicable1 country
- Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income CountriesRecruitingNCT063951293 countries
- Study on Retention in Care and on Clinical Chracteristics of HIV-infected Women Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIKWO).Not yet recruitingNCT078599041 country