Psoriasis clinical trials
The registry lists 2,028 studies for Psoriasis across more than 10 countries. 275 are recruiting or about to start. 1,780 of them are mainly about Psoriasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Arthritis, Psoriatic too: 2,500 studies, 377 open.
ClinicalTrials.gov finds 2,577 studies for Psoriasis. How that becomes 2,027 here
This page counts the studies the registry files under Psoriasis, and those it files under no condition that list Psoriasisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,577Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −466Filed under a narrower condition, counted on its own pageArthritis, Psoriatic 466
- −56List Psoriasis as a condition, but the registry did not file them under itMost often written as “Plaque Psoriasis” (20), “Psoriasis Vulgaris” (16), and “Chronic Plaque Psoriasis” (4). The registry filed them under other conditions only, most often Pruritus (11) and Skin Diseases (8).
- −28Match it another way26 name it in the title and 2 in a keyword.
- 2,027The count on this page558 of them list Psoriasis in their own words; the registry filed them under no condition.
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Status
Who runs them
LEO Pharma (79) · Novartis Pharmaceuticals (64) · Amgen (61) · AbbVie (51) · Pfizer (50) · Bristol-Myers Squibb (40) · Eli Lilly and Company (31) · Janssen Research & Development, LLC (30)
What is being tested here
Drugs under test in Psoriasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Methotrexate | 7 | 6 | 24 |
| Guselkumab | 5 | 10 | 23 |
| Adalimumab | 4 | 18 | 37 |
| Apremilast | 4 | 13 | 33 |
| Ustekinumab | 4 | 14 | 26 |
| Deucravacitinib | 4 | 9 | 21 |
| Tofacitinib | 4 | 9 | 18 |
| Secukinumab | 3 | 22 | 42 |
| Bimekizumab | 3 | 8 | 17 |
| HS-10374 | 3 | 1 | 5 |
Drug classes tested here JAK inhibitors 11 open · Tyrosine kinase inhibitors (TKIs) 10 open · Antimetabolites 7 open · GLP-1 receptor agonists 3 open · Corticosteroids 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Study to Assess Efficacy, Safety and Tolerability of a Nail Patch in Patients With Nail Fragility, Mychosis, Psoriasis · Phase 3 · Wooshin Labottach Co., Ltd.
- Nov 2026A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase Ⅲ Study to Evaluate the Efficacy and Safety of WD-890 Tablets for the Treatment of Moderate to Severe Plaque Psoriasis · Phase 3 · Zhejiang Wenda Pharma Technology LTD.
- Dec 2026Efficacy of Crisaborole 2% Ointment Versus Tacrolimus 0.1% Ointment in the Treatment of Intertriginous and/or Anogenital Psoriasis. · Phase 3 · Cairo University
- Jan 2027Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant) · Phase 3 · Wake Forest University Health Sciences
- Jan 2027A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of RSS0393 Ointment in Adult Patients With Plaque Psoriasis. · Phase 3 · Reistone Biopharma Company Limited
- Mar 2027A Study of HS-20137 in Participants with Moderate-to-severe Plaque Psoriasis · Phase 3 · Hansoh BioMedical R&D Company
- Apr 2027A Phase III Study of SYHX1901 Tablets in the Treatment of Moderate to Severe Plaque Psoriasis · Phase 3 · CSPC Ouyi Pharmaceutical Co., Ltd.
- May 2027A Study of Zasocitinib in Adults With Non-pustular Palmoplantar Psoriasis · Phase 3 · Takeda
- Jul 2027A Clinical Study to Evaluate the Efficacy and Safety of D-2570 in the Treatment of Moderate to Severe Plaque Psoriasis · Phase 3 · InventisBio Co., Ltd
- Jul 2027Evaluate the Efficacy and Safety of D-2570 in Subjects With Moderate to Severe Plaque Psoriasis · Phase 3 · InventisBio Co., Ltd
Who these studies take
Of the 174 Psoriasis studies recruiting now, 91 (52%) set no upper age limit and 67 (39%) stop at 75 or younger. 25 (14%) take children under 18. 4 (2%) are for women only and 0 (0%) for men only; 40 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 17 (10%) | 15 (9%) |
| 18 | 163 (94%) | 160 (92%) |
| 30 | 167 (96%) | 164 (94%) |
| 40 | 169 (97%) | 165 (95%) |
| 50 | 168 (97%) | 165 (95%) |
| 65 | 158 (91%) | 155 (89%) |
| 75 | 127 (73%) | 124 (71%) |
| 85 | 103 (59%) | 100 (57%) |
Across all 2,028 studies, recruiting or not: 38% stop at 75 or younger and 21% at 65; 11% take children; 1% are for women only and 2% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Psoriasis studies take
Of 227 phase 3 interventional studies under Psoriasis, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 10 mo5–17 · 155 studies | 10 mo4–16 · 137 studies | — |
| Phase 1/2 | 9 mo3–21 · 15 studies | — | — |
| Phase 2 | 14 mo9–23 · 174 studies | 12 mo9–20 · 145 studies | 36 mo20–43 · 29 studies |
| Phase 3 | 15 mo10–26 · 227 studies | 15 mo10–26 · 217 studies | — |
| Phase 4 | 23 mo12–43 · 115 studies | 22 mo11–29 · 40 studies | 25 mo14–49 · 75 studies |
| Interventional, no phase | 19 mo8–38 · 134 studies | — | 21 mo10–41 · 115 studies |
| Observational | 37 mo23–93 · 173 studies | 37 mo23–74 · 81 studies | 43 mo17–119 · 92 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting2
- A Study of HL40626S Tablets in Healthy AdultsOct 29, 2026NCT07736586
- A Clinical Trial of MK-8644 in Healthy Participants and Participants With Psoriasis (MK-8644-001)Oct 27, 2026NCT07850310
Results posted2
Newly registered9
- VEGF and Nailfold Changes in PsoriasisNov 9, 2026NCT07925957
- A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same DoseNov 6, 2026NCT07920861
- Cosmetic Efficacy Evaluation of Hydraporin AI Cream in Individuals With Atopic Dermatitis and PsoriasisNov 5, 2026NCT07918560
- Comparison of Efficacy and Safety of Deucravacitinib Versus Methotrexate in the Treatment of Moderate-to-Severe Plaque Psoriasis .Nov 4, 2026NCT07915492
- A Study to Assess the Safety and Effectiveness of COL-5671-PRO Capsules in Adults With Moderate-to-Severe Plaque PsoriasisNov 3, 2026NCT07914231
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- Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release FormulationNov 2, 2026NCT07908641
- Efficacy and Flexibility of Tildrakizumab Treatment in Patients With Moderate-to-severe Plaque Psoriasis and High Disease BurdenOct 28, 2026NCT07900659
- Efficacy of Crisaborole 2% Ointment Versus Tacrolimus 0.1% Ointment in the Treatment of Intertriginous and/or Anogenital Psoriasis.Oct 23, 2026NCT07892339
- Definition of Novel Optoacoustic Biomarkers of Psoriasis and Psoriatic ArthritisOct 21, 2026NCT07885345
Studies
Recruiting first, then most recently updated. Showing 50 of 2,028. Browse all 2,028 → or search them.
- A Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Moderate to Severe Psoriatic ArthritisRecruitingNCT07801495Phase 21 country
- A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar PustulosisRecruitingNCT07013201Phase 25 countries
- A Study to Estimate Secukinumab Retention Rate in Psoriasis Patients With MASLDRecruitingNCT076830651 country
- Thera-Clean® Microbubbles System in Patients With Skin DiseasesEnrolling by invitationNCT07050810Early Phase 11 country
- A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same DoseRecruitingNCT07920861Phase 11 country
- A Study to Evaluate the Efficacy and Safety of CS32582 in Participants With Moderate to Severe Plaque PsoriasisRecruitingNCT07129382Phase 1/21 country
- Efficacy of Fractional Co2 Laser With Topical Tacrolimus 0.1 in the Treatment of Nail PsoriasisNot yet recruitingNCT07919873Not applicable
- Assessing Psoriasis Treatment OutcomesNot yet recruitingNCT07391423Not applicable1 country
- Cosmetic Efficacy Evaluation of Hydraporin AI Cream in Individuals With Atopic Dermatitis and PsoriasisNot yet recruitingNCT07918560Not applicable1 country
- A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)RecruitingNCT06857942Phase 41 country
- A Study of Zasocitinib in Adults With Non-pustular Palmoplantar PsoriasisNot yet recruitingNCT07752108Phase 3
- Metabolic Profiling of Immune Responses in Immune-mediated DiseasesRecruitingNCT048648861 country
- A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in RomaniaRecruitingNCT075827831 country
- A Study of Guselkumab Given After Ustekinumab in Participants With Moderate to Severe Psoriasis in Routine Clinical PracticeRecruitingNCT077465831 country
- A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA TherapeuticallyRecruitingNCT07654751Phase 41 country
- A Study to Assess the Safety and Effectiveness of COL-5671-PRO Capsules in Adults With Moderate-to-Severe Plaque PsoriasisNot yet recruitingNCT07914231Phase 21 country
- Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release FormulationNot yet recruitingNCT07908641Phase 1
- A Study of HL40626S Tablets in Healthy AdultsRecruitingNCT07736586Phase 11 country
- Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)RecruitingNCT07116967Phase 325 countries
- Collection of Samples From Subjects With Various Skin Conditions and Healthy VolunteersRecruitingNCT059949761 country
- PsoBest - The German Psoriasis RegistryRecruitingNCT018480281 country
- Efficacy of Crisaborole 2% Ointment Versus Tacrolimus 0.1% Ointment in the Treatment of Intertriginous and/or Anogenital Psoriasis.Not yet recruitingNCT07892339Phase 31 country
- A Clinical Trial of MK-8644 in Healthy Participants and Participants With Psoriasis (MK-8644-001)RecruitingNCT07850310Phase 11 country
- A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque PsoriasisRecruitingNCT06979453Phase 316 countries
- A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque PsoriasisRecruitingNCT04772079Phase 313 countries
- An Open-Label Extension Study of ORKA-001 in Participants With Plaque PsoriasisRecruitingNCT07449702Phase 22 countries
- Topical Diacerein in Psoriasis VulgarisRecruitingNCT07352306Phase 41 country
- Definition of Novel Optoacoustic Biomarkers of Psoriasis and Psoriatic ArthritisNot yet recruitingNCT07885345Not applicable
- An Open-label Study of HS-20137 in Participants With Moderate-to-Severe Plaque PsoriasisRecruitingNCT07879885Phase 21 country
- Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.RecruitingNCT078585911 country
- A Prospective, Interventional, Exploratory Study Evaluating the Efficacy of Small-Molecule Compound XJH05 Ointment in the Treatment of Plaque PsoriasisRecruitingNCT07780929Not applicable1 country
- A Study of HCXT-2001 Tablets and HCXT-2001 Tablets(A) in Healthy AdultsNot yet recruitingNCT07792928Phase 11 country
- Pentoxifylline Add-On Therapy for Mild-to-Moderate Plaque PsoriasisNot yet recruitingNCT07626788Not applicable1 country
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 12 countries
- An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail PsoriasisRecruitingNCT07725822Phase 41 country
- Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque PsoriasisRecruitingNCT070391108 countries
- A Study to Assess Deucravacitinib Safety in PregnancyRecruitingNCT070176991 country
- Role of Glucose Metabolism in Migration of Cutaneous Dendritic Cells in PsoriasisRecruitingNCT05399433Not applicable1 country
- Early Intervention in Plaque Psoriasis: is Bimekizumab Able to Delay Chronic Inflammation?RecruitingNCT06742333Phase 21 country
- Ceramol PSOR Cream as an Adjuvant Treatment in Patients With Mild-to-Moderate Psoriasis Treated With Narrowband UVB Phototherapy (CERAMOL PSOR CREMA)Not yet recruitingNCT07849101Not applicable1 country
- Evidencing Vibroacoustic Sensing for Inflammatory Skin Disease MonitoringNot yet recruitingNCT078468131 country
- Modifying PEST for Psoriatic Arthritis ScreeningRecruitingNCT06382051Not applicable1 country
- Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology PatientsRecruitingNCT06702293Not applicable1 country
- Global Healthcare Study on PsoriasisRecruitingNCT076340161 country
- A Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of HRS-4139 in Healthy ParticipantsRecruitingNCT07802964Phase 11 country
- Comparative Study on Unani Formulation Vs Active Control in Plaque PsoriasisNot yet recruitingNCT07841314Phase 21 country
- Evaluation of the Efficacy and Safety of Bimekizumab (BZK) or Adalimumab (ADA) in the Treatment of Anterior Chest Wall Pain Associated With Active Axial Spondyloarthritis Refractory to NSAIDs With Hypothesis of Superiority of BimekizumabNot yet recruitingNCT07836283Phase 31 country
- Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque PsoriasisRecruitingNCT07362017Phase 31 country
- Patient Study to Evaluate the Safety and Emollient Performance of Doublebase Once in the Treatment of PsoriasisNot yet recruitingNCT07817394Not applicable
- Impact of Tildrakizumab on Patient Reported Outcomes in Patients With Moderate-to-severe Psoriasis in CanadaRecruitingNCT073707661 country