Keratitis clinical trials
The registry lists 108 studies for Keratitis across more than 10 countries. 19 are recruiting or about to start. 73 of them are mainly about Keratitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its 3 narrower conditions too, such as Keratoconjunctivitis Sicca: 261 studies, 31 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Dompé Farmaceutici S.p.A (4) · National Eye Institute (NEI) (4) · Assiut University (3) · Sohag University (3) · University of California, San Francisco (3) · Stanford University (2) · Ohio State University (2) · Peschke GmbH (2)
What is being tested here
Drugs under test in Keratitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Pattern of Microbial Keratitis in Assiut University Hospital · Assiut University
- Dec 2026A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis · Krystal Biotech, Inc.
- Dec 2026A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis · Shanghai BDgene Co., Ltd.
- Jan 2027Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection · CHU de Reims
- Feb 2027A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis · TearSolutions, Inc.
- Apr 2027Validation of Interleukins and Other Cytokines Together With OCT Imaging for Rapid Infectious Keratitis Assessment · Johannes Kepler University of Linz
Who these studies take
Of the 9 Keratitis studies recruiting now, 6 (67%) set no upper age limit and 1 (11%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 9 (100%) | 9 (100%) |
| 30 | 9 (100%) | 9 (100%) |
| 40 | 9 (100%) | 9 (100%) |
| 50 | 9 (100%) | 9 (100%) |
| 65 | 9 (100%) | 9 (100%) |
| 75 | 8 (89%) | 8 (89%) |
| 85 | 8 (89%) | 8 (89%) |
Across all 108 studies, recruiting or not: 15% stop at 75 or younger and 7% at 65; 27% take children; 0% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Keratitis studies take
Of 16 observational studies under Keratitis, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo5–24 · 12 studies | — | — |
| Observational | 24 mo14–34 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 108. Browse all 108 → or search them.
- Validation of Interleukins and Other Cytokines Together With OCT Imaging for Rapid Infectious Keratitis AssessmentRecruitingNCT056202641 country
- Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal KeratitisNot yet recruitingNCT06463678Phase 2
- A Clinical Study to Evaluate the Safety and Effectiveness of MSCohi-O Lens in the Treatment of Immune-related Ocular Surface Diseases.Not yet recruitingNCT07902687Phase 1
- A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic KeratitisRecruitingNCT07568730Phase 21 country
- RB-PDT for Fusarium Keratitis: The LUMIERE StudyNot yet recruitingNCT07743489Phase 33 countries
- Stromal Lenticule Implantation for Management of Herpetic Stromal KeratitisEnrolling by invitationNCT05156151Not applicable1 country
- Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface DiseasesNot yet recruitingNCT076948171 country
- A Phase II Study of STSP-0902 Ophthalmic Solution in Patients With Neurotrophic KeratitisRecruitingNCT06975748Phase 21 country
- Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious KeratitisNot yet recruitingNCT07452588Not applicable
- A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic KeratitisRecruitingNCT06999733Phase 1/21 country
- Pattern of Microbial Keratitis in Assiut University HospitalNot yet recruitingNCT07316244
- Complex Ocular Infection, Optimization of Microbiological DiagnosisRecruitingNCT054323361 country
- Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot StudyNot yet recruitingNCT07073729Not applicable1 country
- A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal KeratitisRecruitingNCT06474442Phase 21 country
- Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic KeratitisRecruitingNCT05927428Phase 21 country
- Use of a New Method for the Microbiological Diagnosis of Severe Corneal InfectionRecruitingNCT058889871 country
- Acanthamoeba and Artificial IntelligenceNot yet recruitingNCT06332703
- Non-invasive Diagnostics of Microbial KeratitisRecruitingNCT063648781 country
- Pack Cross Linking for Infectious KeratitisNot yet recruitingNCT05881187Not applicable1 country
- Evaluation of Next-Generation Sequencing-based Metabarcoding Versus Culturing for Microbiological Assessment in Infectious KeratitisCompletedNCT051839061 country
- REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult PatientsCompletedNCT04276558Phase 27 countries
- Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction IIActive, not recruitingNCT06271772Phase 32 countries
- Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis SubjectsCompletedNCT04909450Phase 1/22 countries
- Intrastromal Injection of Fluconazole in Treatment of Fungal KeratitisCompletedNCT07557966Not applicable1 country
- A Study of STSP-0902 Ophthalmic Solution in Healthy SubjectsCompletedNCT06597422Phase 11 country
- DEFENDO Long Term Follow-up Study in Stage 1 NK PatientsCompletedNCT055522611 country
- Mycotic Antimicrobial Localized Injection for Treatment of Corneal UlcersCompletedNCT02731638Phase 32 countries
- OCS-01 in Treating Inflammation and Pain in Post-cataract PatientsCompletedNCT04130802Phase 21 country
- Microbial Keratitis Sampling for Biomarker DiscoveryCompletedNCT058888831 country
- The Role of Adjuvant Corneal Crosslinking in the Management of Infective KeratitisCompletedNCT06967376Early Phase 11 country
- Automated Quantitative Ulcer Analysis StudyCompletedNCT044209622 countries
- Corneal Nerves After Treatment With CenegerminCompletedNCT046275711 country
- Efficacy and Safety of Plasma Rich in Growth Factors (PRGF-Endoret) Eye-drops in the Treatment of Neurotrophic KeratitisWithdrawnNCT02707120Phase 41 country
- Steroids and Cross-linking for Ulcer TreatmentCompletedNCT04097730Phase 32 countries
- A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye DiseaseCompletedNCT04391894Phase 21 country
- Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic KeratitisWithdrawnNCT06411145Phase 4
- The Effects of a Large Language Model on Clinical Questioning SkillsCompletedNCT06229379Not applicable1 country
- Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Treatment-Resistant KeratitisTerminatedNCT05250583Phase 21 country
- 3-year Study in Dry Eye Disease Patients With Severe Keratitis Receiving Ikervis® (1mg/mL Ciclosporin)CompletedNCT04144413Phase 37 countries
- Clinical Outcomes of Cyclosporine Eye Drops in Management of Herpetic KeratitisCompletedNCT05720715Phase 41 country
- Safety of Overnight Corneal Reshaping LensesCompletedNCT01272271
- Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.CompletedNCT01756456Phase 1/26 countries
- Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe KeratitisCompletedNCT03237936Phase 41 country
- OCT Evaluation of Neurotrophic Ulcer Following Treatment With OxervateStatus unknownNCT045736471 country
- CDL Validation StudyCompletedNCT054614691 country
- Topical Insulin Drops for the Treatment of Neurotrophic Keratopathy.WithdrawnNCT05321251Phase 2/31 country
- Deep Learning for the Discrimination Among Different Types of Keratits: a Nationwide StudyCompletedNCT055387931 country
- Besifloxacin in Bacterial KeratitisCompletedNCT02497365Not applicable1 country
- Efficacy of Mutilayered Fresh Amnoitic Membrane Transplantation in Resistant Fungal KeratitisCompletedNCT06070883Not applicable1 country
- Microbiological Diagnosis of Infectious Keratitis to Pathogenic Fastidious GermsCompletedNCT02819232Not applicable1 country