Premature Ejaculation clinical trials

The registry lists 100 studies for Premature Ejaculation across more than 10 countries. 17 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-15.

Studies

Recruiting first, then most recently updated. Showing 50 of 100 — search for more.

• Ejaculatory and Orgasmic Dysfunction RegistryRecruitingNCT066054691 country
• Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE)RecruitingNCT07434271Phase 21 country
• Evaluate the Efficacy and Safety of VV913 Capsules in the Treatment of PENot yet recruitingNCT07722780Phase 21 country
• Male Pelvic Floor Muscle Rehabilitation ExercisesNot yet recruitingNCT07451808Not applicable
• Pelvic Floor Therapies for Lifelong Premature EjaculationRecruitingNCT07627438Not applicable1 country
• Effect of Prostatic Urethra and Seminal Vesicle Morphometry on EjaculationNot yet recruitingNCT076148541 country
• The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature EjaculationRecruitingNCT07442396Not applicable1 country
• Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation.RecruitingNCT06425211Not applicable1 country
• Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized StudyNot yet recruitingNCT07236632Not applicable
• Comparison of the Efficacy and Safety of Dapoxetine, Kegel Exercises, and Acupuncture in the Treatment of Premature Ejaculation: A Randomized, Double-Blind, Placebo-Controlled TrialNot yet recruitingNCT07067970Not applicable1 country
• Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination Therapy Versus MonotherapyNot yet recruitingNCT07057011Not applicable1 country
• Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical TrialRecruitingNCT06570135Not applicable1 country
• Development and Validation of an Anxiety Disorder Prediction Model for Premature Ejaculation PatientsRecruitingNCT066778141 country
• Clinical Study to Reduce Premature Ejaculation in Healthy Adult MenNot yet recruitingNCT06571318Not applicable
• Effectiveness and Safety of TENS Therapy for Premature EjaculationRecruitingNCT06425224Phase 31 country
• The Study on the Effectiveness and Safety of Electroacupuncture at ST36 in Treating Primary Premature EjaculationRecruitingNCT06172855Not applicable1 country
• Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature EjaculationNot yet recruitingNCT05052879Phase 3
• Silicone Band Versus Prilocaine Spray for Lifelong Premature EjaculationCompletedNCT07820865Not applicable1 country
• Extracorporeal Magnetic Innervation Plus Pelvic Floor Muscle Training for Premature EjaculationCompletedNCT07385222Not applicable1 country
• Impact of Depression Severity on Sexual DysfunctionActive, not recruitingNCT076274771 country
• Vagus Nerve Stimulation in Premature EjaculationCompletedNCT07300774Not applicable1 country
• Transcutaneous Posterior Tibial Nerve Stimulation for Premature EjaculationCompletedNCT04207723Not applicable1 country
• Dual-Site Botulinum Toxin Type A Injection for Lifelong Premature EjaculationCompletedNCT07426640Not applicable1 country
• Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature EjaculationCompletedNCT07113145Phase 41 country
• On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature EjaculationCompletedNCT07081659Phase 2/31 country
• THE IMPACT OF VITAMIN B12 TREATMENT ON EJACULATORY FUNCTIONS IN MEN: SYMPTOMATIC RELIEF AND IMPROVED OUTCOMESCompletedNCT070364971 country
• Primary Premature Ejaculation GeneticsCompletedNCT02109302Not applicable1 country
• Safety and Efficacy of Botulinum Toxin-A Injection Into Ischiocavernosus Muscle for Premature EjaculationActive, not recruitingNCT06851598Phase 2/31 country
• A Comparative Study of Selective Dorsal Neurectomy, Pulsed Radiofrequency Neuromodulation, and Intragranular Hyaluronic Acid Injection for Premature EjaculationCompletedNCT06777199Not applicable1 country
• The Asia-Pacific Flexible Dose Study of Dapoxetine and Patient Satisfaction in Premature Ejaculation TherapyCompletedNCT01063881Phase 33 countries
• Transcutaneous Electrical Nerve Stimulation for the Treatment of Premature EjaculationCompletedNCT06570512Not applicable1 country
• TPTNS for Treating Patients With Premature EjaculationCompletedNCT03204890Not applicable1 country
• The Effect of Behavioral Therapy Given to Men and Their Partners'CompletedNCT05964608Not applicable1 country
• The Prevalence of Erectile Dysfunction (ED) and Premature Ejaculation (PE) in PolandCompletedNCT054621711 country
• Precise Use of Lidocaine Cream to Treat Primary Premature EjaculationStatus unknownNCT05749614Not applicable1 country
• Effect of Respiratory Exercises On The Intravaginal Ejaculation Latency TimeCompletedNCT05517694Not applicable1 country
• Sildenafil Added Effect in Dapoxetine Non-responding Mono-symptomatic Premature Ejaculation (PE)Status unknownNCT05556083Phase 2
• PSD502 in Subjects With Premature EjaculationCompletedNCT03578783Phase 21 country
• The Safety of Dapoxetine/Tadalafil Combination TherapyStatus unknownNCT03177746Phase 41 country
• Combined On-demand Sildenafil Citrate and Tramadol Hydrochloride for Treatment of Premature EjaculationStatus unknownNCT05183334Phase 4
• Erectile Dysfunction, Psychological Disorders, and Sexual Performance Among Men Seeking Medical Help for FertilityStatus unknownNCT049416901 country
• Chronotype and Premature EjaculationCompletedNCT048413951 country
• Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.CompletedNCT04355949Not applicable1 country
• Effectiveness and Tolerability of the On-demand Use of Combined Dapoxetine With Tadalafil and Combined Dapoxetine With Lidocaine 5% Spray in Treatment of Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Alone.Status unknownNCT04703127Phase 31 country
• Consultations Reason for Genital, Urinary or Psychological Humans in General PracticeTerminatedNCT02378779Not applicable1 country
• Evaluation of the Safety and Effectiveness of the vPatch DeviceCompletedNCT03942367Not applicable2 countries
• IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT) and Patient Reported Outcomes in Men With Premature Ejaculation (PE)CompletedNCT02232425Phase 22 countries
• Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile DysfunctionStatus unknownNCT04361305Phase 3
• Efficacy of App and Electronic Device in the Treatment of Premature EjaculationCompletedNCT04012437Not applicable1 country
• A Multicenter Case-control Study of Risk Factors for Premature Ejaculation in China's Shaanxi ProvinceStatus unknownNCT042351921 country