Drug
Omega-N-Methylarginine clinical trials
Also written L-NMMA and NG-monomethyl-L-arginine.
Includes 1 study of N(G)-monomethylarginine acetate.
- studies test it
- 30
- open now
- 2
- in phase 3
- 2
- first study started
- 2000
Keep track of what changes. Save the omega-N-Methylarginine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
26 studies that test it; most in 2005 (4)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2002 | 3 |
| 2003 | 1 |
| 2005 | 4 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 3 |
| 2012 | 1 |
| 2013 | 3 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 1 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 13
- Phase 2
- 6
- Phase 3
- 2
- Phase 4
- 2
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 29
Regional Hospital Holstebro (7) · The Methodist Hospital Research Institute (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Vanderbilt University (3) · Medical University of Vienna (3) · New York Medical College (1) · University of Wisconsin, Madison (1) · University Health Network, Toronto (1)
Often tested with
Tested in the same studies.
Phenylephrine (3) · Acetylcholine (3) · Nitroprusside (3) · Bradykinin (3) · Pembrolizumab (1) · Ambrisentan (1) · Teduglutide (1) · Pegvisomant (1)
Studies
Open first, then newest update. How each study uses omega-N-Methylarginine is read from its arms, and is right about nine times in ten.
Testing it · 30
- : Vascular Function in Health and DiseaseRecruitingPhase 1D. Walter WrayNCT02966665Written as BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate
- Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)RecruitingPhase 2The Methodist Hospital Research InstituteNCT05660083Written as L-NMMA
- Phase Ib of L-NMMA and PembrolizumabCompletedPhase 1The Methodist Hospital Research InstituteNCT03236935Written as L-NMMA
- Mechanisms of Vasovagal SyncopeCompletedEarly Phase 1New York Medical CollegeNCT01791816Written as L-Ng-monomethyl Arginine (L-NMMA)
- L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer PatientsCompletedPhase 1/2The Methodist Hospital Research InstituteNCT02834403Written as L-NMMA
- Mechanisms of Cerebrovascular ControlCompletedPhase 1University of Wisconsin, MadisonNCT02936687Written as NOS Inhibition
- Niacin to Improve Blood Flow in People With Sickle Cell DiseaseCompletedPhase 2National Heart, Lung, and Blood Institute (NHLBI)NCT00508989Written as L-NMMA
- L-NMMA on GLP-2 Mediated Intestinal Lipoprotein ReleaseCompletedPhase 2/3University Health Network, TorontoNCT03534661Written as Teduglutide + L-NMMA
- Endothelial Hyperpolarization in HumansTerminatedPhase 2Emory UniversityNCT00166166Written as L-NG-monomethyl Arginine (L-NMMA)
- Effect of DPP4 Inhibition on Growth Hormone SecretionCompletedPhase 4Vanderbilt UniversityNCT01701973Written as L-NMMA
- Endothelial Function in Lower Extremity Bypass GraftsCompletedNot applicableBrigham and Women's HospitalNCT00759707Written as L-N^G monomethyl arginine (L-NMMA)
- Pathophysiology of Cardiometabolic Risk Factors in African AmericansCompletedPhase 1Vanderbilt University Medical CenterNCT01122407Written as L-NMMA
- Insulin and Sarcopenia in the ElderlyCompletedPhase 1The University of Texas Medical Branch, GalvestonNCT00690534Written as L-NMMA
- Does eNOS Gene Polymorphism Play a Role in the Maintenance of Basal Vascular Tone in the Choroid or Optic Nerve Head?TerminatedEarly Phase 1Medical University of ViennaNCT00708357Written as NG-monomethyl-L-arginine
- Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy HumansTerminatedNot applicableMedical University of ViennaNCT00914394Written as NG-monomethyl-L-arginine (L-NMMA)
- Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor BlockadesCompletedPhase 1Uppsala UniversityNCT02245165Written as L-Nitro-Monomethyl-Arginine (LNMMA) 10 mg/kg IV
- Effect of Renal Denervation on NO-mediated Sodium Excretion and Plasma Levels of Vasoactive HormonesStatus unknownNot applicableRegional Hospital HolstebroNCT01617551Written as NG-monomethyl-L-arginine (L-NMMA)
- Nitric Oxide and the Autonomic Nervous SystemCompletedNot applicableVanderbilt UniversityNCT00178919Written as L-NMMA
- Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3CompletedNot applicableVanderbilt UniversityNCT00685945Written as L-NMMA + bradykinin
- Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy HumansCompletedNot applicableMedical University of ViennaNCT00806741Written as NG-monomethyl-L-arginine (L-NMMA)
See all 30 studies that test omega-N-Methylarginine →
Given in every arm · 3 — omega-N-Methylarginine is usual care beside what is tested
- Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)TerminatedPhase 2GlaxoSmithKlineNCT03446612Written as L-N-monomethyl arginine acetate (L-NMMA)
- Plasma Triglyceride Extraction by The MuscleCompletedPhase 1Mayo ClinicNCT01860911Written as NG-monomethyl-L-arginine
- Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow RegulationWithdrawnPhase 1University of Wisconsin, MadisonNCT03066115Written as L-NMMA
As the comparator · 1 — what is tested is compared with omega-N-Methylarginine
Codes
What other systems call omega-N-Methylarginine · ClinicalTrials.gg INT008681
- MeSH (NLM) D019323omega-N-MethylarginineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 27JT06E6GRTILARGININEConfirmed FDA, NLM
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D019323 | omega-N-Methylarginine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 27JT06E6GR | TILARGININE | Confirmed FDA, NLM |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.