Lorcaserin clinical trials
Also written Belviq and APD356.
How each study uses lorcaserin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
47 studies that test it; most in 2008 (6)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 6 |
| 2013 | 4 |
| 2014 | 6 |
| 2015 | 6 |
| 2016 | 4 |
| 2017 | 5 |
| 2018 | 5 |
| 2019 | 5 |
| 2020 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 21 · Other 26
Eisai Inc. (17) · New York State Psychiatric Institute (4) · Mayo Clinic (3) · Virginia Commonwealth University (2) · National Institute on Drug Abuse (NIDA) (2) · Duke University (2) · The Mind Research Network (2) · Beth Israel Deaconess Medical Center (1)
Often tested with
Tested in the same studies.
Phentermine (1) · Nicotine Patch (1) · Nicotine (1) · Varenicline (1) · Cocaine (1) · Orange (1) · Metformin (1) · Ziprasidone (1)
Related medicines
As reviewed, each with the page that says it.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test lorcaserin.
- Jun 2027Lorcaserin in Obesity: Identification of CNS Targets Using fMRIPhase 4 · Beth Israel Deaconess Medical Center
Studies
Open first, then newest update. How each study uses lorcaserin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 47
- Lorcaserin in Obesity: Identification of CNS Targets Using fMRIActive, not recruitingPhase 4Beth Israel Deaconess Medical CenterNCT02400359Written as Lorcaserin HCl
- Rebalancing the Serotonergic System in Cocaine DependenceWithdrawnPhase 1Mclean HospitalNCT03266939Written as Lorcaserin
- A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet SyndromeTerminatedPhase 3Eisai Inc.NCT04572243Written as Lorcaserin
- Predictors of Lorcaserin-Induced Weight LossTerminatedPhase 4Columbia UniversityNCT03353220Written as Belviq
- Treatment With Lorcaserin for Cocaine Use: The TLC StudyTerminatedPhase 2Glenn-Milo SantosNCT03192995Written as lorcaserin
- Pharmacokinetic Properties of Lorcaserin in Obese or Overweight Elderly SubjectsCompletedPhase 1Eisai Inc.NCT00828581Written as lorcaserin
- Mechanisms of Lorcaserin for Smoking CessationTerminatedPhase 2The Mind Research NetworkNCT04396834Written as Lorcaserin Oral Tablet
- Laboratory Screening of Lorcaserin for Alcohol Use DisorderTerminatedPhase 2The Mind Research NetworkNCT04396847Written as Lorcaserin Oral Tablet
- Effect of Lorcaserin on Cannabis Withdrawal and Self-administrationCompletedPhase 1/2New York State Psychiatric InstituteNCT03253926Written as Lorcaserin
- Lorcaserin and Behavioral Modification for Overweight and Obesity Management in Chinese Obese PatientsTerminatedPhase 3Kanion & Huawe Medicine Co.,LtdNCT03720574Written as Lorcaserin 10 mg BID
- Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 YearsTerminatedPhase 4Eisai Inc.NCT03338296Written as lorcaserin hydrochloride XR
- Addressing Post Cessation Weight GainTerminatedPhase 2/3Mayo ClinicNCT02412631Written as lorcaserin
- MEtformin and Lorcaserin for WeighT Loss in SchizophreniaTerminatedPhase 4University of North Carolina, Chapel HillNCT02796144Written as Lorcaserin
- Lorcaserin for Cannabis Use DisorderTerminatedEarly Phase 1New York State Psychiatric InstituteNCT03637842Written as Lorcaserin
- Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast CancerWithdrawnPhase 1Ohio State University Comprehensive Cancer CenterNCT04205071Written as Lorcaserin
- Drug Interaction and Subjective Effects of Compounds for Opioid Use DisorderCompletedPhase 1Virginia Commonwealth UniversityNCT03143855Written as Lorcaserin
- Lorcaserin in Combination With XR-Naltrexone for Relapse Prevention in Opioid Use DisorderCompletedPhase 2/3New York State Psychiatric InstituteNCT03169816Written as Lorcaserin
- Lorcaserin in the Treatment of Cocaine Use DisorderCompletedPhase 2National Institute on Drug Abuse (NIDA)NCT03007394Written as Lorcaserin
- Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use DisorderTerminatedPhase 1Virginia Commonwealth UniversityNCT03143543Written as Group A Lorcaserin (10mg)
- Gene-by-Stress Interactions in Intervention Studies SignificanceTerminatedPhase 1Duke UniversityNCT03011645Written as Lorcaserin
See all 47 studies that test lorcaserin →
Given beside what is tested · 1 — lorcaserin is usual care or a partner of the new treatment
Codes
What other systems call lorcaserin · ClinicalTrials.gg INT004853
- MeSH (NLM) C506658lorcaserinOne source NLM
- UNII (FDA) 637E494O0ZLORCASERINConfirmed FDA, NLM, Wikidata
- RxNorm 1300701Confirmed FDA, Wikidata
- Wikidata Q340139lorcaserinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C76102LorcaserinOne source FDA
- DrugBank DB04871One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C506658 | lorcaserin | One source NLM |
| UNII (FDA) | 637E494O0Z | LORCASERIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1300701 | — | Confirmed FDA, Wikidata |
| Wikidata | Q340139 | lorcaserin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C76102 | Lorcaserin | One source FDA |
| DrugBank | DB04871 | — | One source Wikidata |
Also registered as lorcaserin hydrochloride anhydrous (UNII 0QJF08GDPE · RxNorm 1300700) and lorcaserin hydrochloride hemihydrate (UNII REV26SR2B4 · RxNorm 1597623).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.