Bunion clinical trials
The registry lists 58 studies for Bunion across more than 10 countries. 5 are recruiting or about to start. 14 of them are mainly about Bunion (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Pacira Pharmaceuticals, Inc (5) · Heron Therapeutics (4) · Baudax Bio (4) · Cali Pharmaceuticals LLC (3) · Assiut University (2) · iX Biopharma Ltd. (2) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Treace Medical Concepts, Inc. (2)
What is being tested here
Drugs under test in Bunion studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| CPL-01 | 1 | 2 | 2 |
| Bupivacaine | 0 | 4 | 8 |
| Liposomal Bupivacaine | 0 | 2 | 5 |
| Meloxicam | 0 | 2 | 4 |
| Tapentadol | 0 | 3 | 4 |
| Dexmedetomidine | 0 | 0 | 3 |
| Ropivacaine | 0 | 2 | 2 |
| HTX-011A | 0 | 0 | 1 |
| HTX-011B | 0 | 0 | 1 |
| HTX-002 | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 10 · Opioids 6 · NSAIDs 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Jun 2027Phase 3 Bunionectomy Study · Phase 3 · Cali Pharmaceuticals LLC
- Mar 2027LSTR in Chevron Osteotomy · The Methodist Hospital Research Institute
- Apr 2027Postsurgical Analgesia After Unilateral Bunionectomy · AmacaThera Inc.
Who these studies take
Of the 1 Bunion studies recruiting now, 0 (0%) set no upper age limit and 1 (100%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (100%) | 1 (100%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 1 (100%) | 1 (100%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 58 studies, recruiting or not: 34% stop at 75 or younger and 16% at 65; 7% take children; 3% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Postsurgical Analgesia After Unilateral BunionectomyNov 10, 2026NCT07858734
Studies
Recruiting first, then most recently updated. Showing 50 of 58. Browse all 58 → or search them.
- Postsurgical Analgesia After Unilateral BunionectomyRecruitingNCT07858734Phase 21 country
- Phase 3 Bunionectomy StudyNot yet recruitingNCT07490496Phase 31 country
- Proximal Metatarsal Osteotomy in Correction of Hallux ValgusNot yet recruitingNCT06584487
- Prospective Study of Minimally Invasive Lapidus Procedure for Hallux Valgus DeformitiesNot yet recruitingNCT06570590Not applicable1 country
- Epidemiology of Bunion and Risk FactorsNot yet recruitingNCT06335459
- Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Pragmatic Clinical TrialCompletedNCT04713098Not applicable1 country
- LSTR in Chevron OsteotomyActive, not recruitingNCT06486753Not applicable1 country
- A Study of TLC590 for Postsurgical Pain Following BunionectomyActive, not recruitingNCT07222748Phase 31 country
- Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot SurgeryCompletedNCT03504462Not applicable1 country
- Dose-Escalation Study of HTX-034 Following BunionectomyCompletedNCT04398329Phase 1/21 country
- CPL-01 in the Management of Postoperative Pain After BunionectomyCompletedNCT05831449Phase 31 country
- Early Weight-Bearing After the Lapiplasty Mini-Incision Procedure (Mini3D)TerminatedNCT05082012Not applicable1 country
- Early Weight-Bearing After the Lapiplasty ProcedureActive, not recruitingNCT03740282Not applicable1 country
- Phase 2 Bunionectomy HTX-011 Administration StudyCompletedNCT03718039Phase 21 country
- Bunionectomy Study for Postoperative Analgesia (EPOCH 1)CompletedNCT03295721Phase 31 country
- Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following BunionectomyCompletedNCT02762929Phase 21 country
- Association of Q Angle and Bunion Deformity of High Heel Wearing Females of Office Working in LahoreCompletedNCT071570461 country
- Hallux Abductus Valgus and Extensor Hallux Longus; Treatment by MIS SurgeryCompletedNCT062434711 country
- Fourth Generation Percutaneous Transverse Osteotomies for Hallux ValgusCompletedNCT066252291 country
- A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical PainCompletedNCT05773846Phase 31 country
- Patient Reported Function Following Combined First MTP and First TMT Arthrodesis.CompletedNCT05527197Not applicable1 country
- Clinical Trial on Patient-Specific-Instrumentation Assisted Lapidus Fusion for Hallux ValgusActive, not recruitingNCT05602844Not applicable1 country
- Post-Operative Pain and Opioid Reduction Trial After BunionectomyCompletedNCT05411861Phase 21 country
- Multi-Plane Hallux Valgus Correction With the Phantom® NailCompletedNCT040842621 country
- Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing BunionectomyCompletedNCT04826328Phase 11 country
- Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity SurgeriesCompletedNCT04518462Phase 31 country
- Timing of Weight Bearing After Hallux Valgus SurgeryCompletedNCT03340415Not applicable1 country
- Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot SurgeryStatus unknownNCT04751344Phase 41 country
- Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing BunionectomyCompletedNCT04002089Phase 11 country
- Liposome Bupivacaine for ANKLE BlocksCompletedNCT03106545Phase 21 country
- Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity SurgeriesWithdrawnNCT03954639Phase 3
- Efficacy of Tranexamic Acid in Foot and Ankle SurgeriesCompletedNCT03653429Phase 41 country
- Minimally Invasive Distal Chevron in Comparison to the Reverdin-Isham Osteotomy for Hallux Valgus CorrectionCompletedNCT042882971 country
- Dexmedetomidine Sedation in Orthopedic SurgeryStatus unknownNCT04149626Phase 21 country
- Measurement of Arch Motion After Bunion SurgeryTerminatedNCT020747481 country
- Intravenous Tapentadol in Post-Bunionectomy PainCompletedNCT01435577Phase 21 country
- Arthroscopic Assisted Lateral Soft Tissue Release for Hallux ValgusCompletedNCT04088214Not applicable1 country
- Ketorolac Effects on Post-operative Pain and Bone HealingTerminatedNCT01133639Not applicable1 country
- Early Weight-Bearing After Lapidus ArthrodesisTerminatedNCT032575401 country
- Study of Wafermine™ for Post-bunionectomy or Abdominoplasty PainCompletedNCT03246971Phase 21 country
- FASTFORWARDTM Bunion Correction System in Treating Hallux Valgus PatientsStatus unknownNCT03594292Not applicable1 country
- Minimally Invasive Versus Open Scarf Osteotomy for Hallux Valgus Correction: a Randomized Controlled TrialStatus unknownNCT03575338Not applicable1 country
- Evaluation of N1539 Following Bunionectomy SurgeryCompletedNCT02675907Phase 31 country
- Placebo-Controlled Evaluation of N1539 Following Bunionectomy SurgeryCompletedNCT02540265Phase 21 country
- Pericapsular Exparel for Pain Relief in Bunionectomy and Related ProceduresTerminatedNCT02499575Not applicable1 country
- Placebo-Controlled Evaluation of Intranasal Dexmedetomidine for Postoperative Analgesia Following Bunionectomy SurgeryCompletedNCT02284243Phase 21 country
- Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.CompletedNCT023508811 country
- Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label ExtensionCompletedNCT01484652Phase 31 country
- Safety and Efficacy Study of COV155 for Post-operative Bunionectomy PainCompletedNCT01743625Phase 31 country
- A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing BunionectomyCompletedNCT02541396Phase 21 country