ClinicalTrials.gg
Not yet recruitingNCT07784608DDIUpdated Sep 10, 2026

A Clinical Trial to Evaluate the Drug-drug Interactions of Co-administered 'HUC2-744-A' and 'HUC2-744-B' in Healthy Adult Volunteers

A Phase 1 interventional study of Atorvastatin Calcium and Telmisartan in Drug-drug Interactions, sponsored by Huons Co., Ltd.. Not yet recruiting at 1 site in South Korea. Open to participants aged 19 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-10.

Sponsored by Huons Co., Ltd. (part of Huons Global) · Phase 1, Interventional, and Basic science

Phase
Phase 1
Study type
Interventional
Enrollment
28
Allocation
Not applicable
Ages
19 Years to 55 Years
Sex
All
01

Study summary

This study aims to evaluate the pharmacokinetic interactions between HUC2-744-A and HUC2-744-B following monotherapy or co-administration under multiple-dose conditions.

Read the detailed description

For selected subjects, the designated investigational products are administered orally with 200 mL of water during Treatment 1 (HUC2-744-A), Treatment 2 (HUC2-744-B), and Treatment 3 (HUC2-744-A + HUC2-744-B).

02

Conditions studied

  • Drug-drug Interactions

Keywords

  • Drug-Drug Interactions
03

In context

Lead sponsor

Huons Co., Ltd. is the lead sponsor of 29 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy adults
  • Subjects with a body weight of 50 kg or more and a within the range of 18.0 to 29.9 kg/m²

Exclusion criteria

Exclusion Criteria:

  • History or presence of cardiovascular, respiratory, hepatic, renal, hematologic, gastrointestinal, endocrine, immunologic, dermatologic, neurological, or psychiatric disease
  • Presence of acute disease symptoms within 28 days prior to the first dosing
  • History of any disease that may affect drug absorption, distribution, metabolism, or excretion
  • or history of clinically significant hypersensitivity to atorvastatin, telmisartan, drugs containing ingredients of the same class, or other medications (e.g., aspirin, antibiotics, dihydropyridine derivatives)
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Clinically significant

Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.

Hypersensitivity

An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.

05

Study design

Phase
Phase 1
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
28 participants (estimated)

Study arms

  • Experimental
    single arm

    IP are administered during Treatment 1 (Atorvastatin), Treatment 2 (Telmisartan), and Treatment 3 (Atorvastatin + Telmisartan)

    Drug: Atorvastatin Calcium · Drug: Telmisartan

Interventions

06

What researchers measure

Primary outcomes

  1. AUCτ

    Area Under the Curve of telmisartan, atorvastatin

    Time frame: Day 22

  2. Cmax,ss

    Maximum concentration at steady state of telmisartan, atorvastatin

    Time frame: Day 22

Secondary outcomes

  1. Cmax,ss

    Maximum concentration at steady state of 2-hydroxy atorvastatin

    Time frame: Day 22

  2. AUCτ

    Area Under the Curve of 2-hydroxy atorvastatin

    Time frame: Day 22

07

Study locations

1 site
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Sep 2026; primary completion for Apr 2027, 7 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 5, 2026
First posted
Aug 25, 2026
StartEst.
Sep 2026
Primary completionEst.
Apr 2027
CompletionEst.
Nov 2027
Last update
Sep 10, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07784608
Lead sponsor
Huons Co., Ltd.
Responsible party
Sponsor
First posted
Aug 25, 2026
Start date
Sep 2026 (estimated)
Primary completion
Apr 2027 (estimated)
Completion
Nov 2027 (estimated)
Last update
Sep 10, 2026

Study contacts

Huons
Contact
jywon@huons.com
+82-70-7492-6023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

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Studies of the drugs tested here: Atorvastatin · Telmisartan

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