Hyperlipidemias clinical trials
The registry lists 861 studies for Hyperlipidemias across more than 10 countries. 110 are recruiting or about to start. 362 of them are mainly about Hyperlipidemias (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 7 narrower conditions too, such as Hypercholesterolemia: 2,409 studies, 272 open.
ClinicalTrials.gov finds 2,430 studies for Hyperlipidemias. How that becomes 861 here
This page counts the studies the registry files under Hyperlipidemias, and those it files under no condition that list Hyperlipidemiasthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,430Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1,479Filed under a narrower condition, counted on its own pageHypercholesterolemia 993 · Hypertriglyceridemia 256 · Hyperlipoproteinemia Type II 155 · Homozygous Familial Hypercholesterolemia 38 · Hyperlipoproteinemias 16 · Hyperlipoproteinemia Type I 13 · 1 more
- −5List Hyperlipidemias as a condition, but the registry did not file them under itMost often written as “Hyperlipemia, Carbohydrate Inducible” (1), “Carbohydrate Inducible Hyperlipemia” (1), and “Hyperlipidemia in Children” (1). The registry filed them under other conditions only, most often Hyperlipoproteinemia Type IV (2) and Hyperlipoproteinemia Type V (2).
- −85Match it another way28 name it in the title, 5 in a keyword, and 52 by a synonym or other text the search reads.
- 861The count on this page15 of them list Hyperlipidemias in their own words; the registry filed them under no condition.
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Status
Who runs them
Pfizer (27) · Takeda (21) · AstraZeneca (20) · Amgen (17) · Novartis Pharmaceuticals (13) · University Health Network, Toronto (11) · University of Toronto (9) · Esperion Therapeutics, Inc. (9)
What is being tested here
Drugs under test in Hyperlipidemias studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Inclisiran | 5 | 7 | 11 |
| Rosuvastatin | 1 | 7 | 28 |
| Simvastatin | 1 | 10 | 14 |
| Bempedoic acid | 1 | 6 | 8 |
| HRS-1301 | 1 | 0 | 5 |
| Colesevelam | 1 | 1 | 5 |
| HRS-7249 | 1 | 0 | 3 |
| Enlicitide | 1 | 2 | 2 |
| SHR-1918 | 1 | 1 | 2 |
| Berberine | 1 | 1 | 1 |
Drug classes tested here Statins 3 open · PCSK9 inhibitors 24 · Angiotensin receptor blockers (ARBs) 12 · Calcium channel blockers 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes · Phase 3 · Novartis Pharmaceuticals
- Mar 2027A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE) · Phase 3 · Madrigal Pharmaceuticals, Inc.
- May 2027Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease · Phase 3 · Novartis Pharmaceuticals
- Jun 2027A Clinical Study to Evaluate the Efficacy and Safety of Bempedoic Acid · Phase 3 · CSPC Ouyi Pharmaceutical Co., Ltd.
- Jul 2027Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy · Phase 3 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Oct 2027A Trial to Evaluate the Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia · Phase 3 · Beijing Suncadia Pharmaceuticals Co., Ltd
- Nov 2027A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque · Phase 3 · NewAmsterdam Pharma
- Nov 2027A Clinical Study of Enlicitide (MK-0616) in Adults With Hyperlipidemia in India (MK-0616-038) · Phase 3 · Merck Sharp & Dohme LLC
- Nov 2026Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance · First Affiliated Hospital Xi'an Jiaotong University
- Dec 2026Penn Medicine Healthy Heart · University of Pennsylvania
Who these studies take
Of the 68 Hyperlipidemias studies recruiting now, 28 (41%) set no upper age limit and 32 (47%) stop at 75 or younger. 8 (12%) take children under 18. 2 (3%) are for women only and 2 (3%) for men only; 16 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (7%) | 5 (7%) |
| 18 | 44 (65%) | 45 (66%) |
| 30 | 53 (78%) | 53 (78%) |
| 40 | 58 (85%) | 58 (85%) |
| 50 | 59 (87%) | 59 (87%) |
| 65 | 53 (78%) | 53 (78%) |
| 75 | 42 (62%) | 42 (62%) |
| 85 | 29 (43%) | 30 (44%) |
Across all 861 studies, recruiting or not: 47% stop at 75 or younger and 29% at 65; 6% take children; 3% are for women only and 7% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperlipidemias studies take
Of 57 phase 3 interventional studies under Hyperlipidemias, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 3 mo1–10 · 54 studies | 3 mo1–10 · 47 studies | — |
| Phase 2 | 16 mo10–27 · 30 studies | — | — |
| Phase 3 | 18 mo11–32 · 57 studies | 18 mo10–26 · 51 studies | — |
| Phase 4 | 28 mo16–44 · 18 studies | — | — |
| Interventional, no phase | 15 mo7–31 · 171 studies | — | 16 mo7–31 · 166 studies |
| Observational | 28 mo11–68 · 35 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting2
- A Study to Evaluate COR-1004 in Adult Volunteers.Oct 26, 2026NCT07229118
- A Clinical Study of Enlicitide (MK-0616) in Adults With Hyperlipidemia in India (MK-0616-038)Oct 22, 2026NCT07821944
Newly registered3
- Comparative Analysis of Chamomile Tea (Matricaria Chamomilla) and Green Tea (Camellia Sinensis) Against HyperlipidemiaOct 30, 2026NCT07907081
- EDIT-401 in Adults Who Require Additional Lowering of Low-Density Lipoprotein Cholesterol (LDL-C)Oct 26, 2026NCT07894887
- MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)Oct 23, 2026NCT07892651
Studies
Recruiting first, then most recently updated. Showing 50 of 861. Browse all 861 → or search them.
- Truway Diagnostic Tools in Primary CareEnrolling by invitationNCT07209527Early Phase 11 country
- A Clinical Study of Enlicitide (MK-0616) in Adults With Hyperlipidemia in India (MK-0616-038)RecruitingNCT07821944Phase 31 country
- Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care Alone for LDL-C Evaluation in Acute Coronary Syndrome Patients in Saudi ArabiaNot yet recruitingNCT07684469Phase 4
- A Study to Evaluate COR-1004 in Adult Volunteers.RecruitingNCT07229118Phase 11 country
- Study of Zodasiran in Adolescent Participants With Homozygous Familial HypercholesterolemiaRecruitingNCT07473843Phase 33 countries
- EDIT-401 in Adults Who Require Additional Lowering of Low-Density Lipoprotein Cholesterol (LDL-C)Not yet recruitingNCT07894887Phase 1/21 country
- Phase 1b Study of VERVE-201 in Patients With Refractory HyperlipidemiaRecruitingNCT06451770Phase 16 countries
- MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)Not yet recruitingNCT078926511 country
- Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)Not yet recruitingNCT07662616Early Phase 1
- A Phase 1 Study of VELA-101 in Adult ParticipantsNot yet recruitingNCT07864311Phase 11 country
- Coronary Artery Calcium (CAC) Testing in Primary CareNot yet recruitingNCT07868809Not applicable1 country
- ECHO for Diabetes and Multiple Chronic Conditions StudyEnrolling by invitationNCT06451458Not applicable1 country
- A Extension Study to Evaluate the Safety and Efficacy of HRS-7249 in Patients With HypertriglyceridemiaRecruitingNCT07799688Phase 21 country
- A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult VolunteersNot yet recruitingNCT07858019Phase 12 countries
- Gauging Outcomes of Total Milk Ingestion on Lipid and gControlRecruitingNCT07087184Not applicable1 country
- PCSK9 Inhibitors in Hyperlipidemia and AtherosclerosisNot yet recruitingNCT07856264
- Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary SyndromesRecruitingNCT07102628Phase 314 countries
- Development and Clinical Validation of Key Technologies for Non-invasive Breath Metabolic Fingerprinting for Large-scale Population Lipid ScreeningNot yet recruitingNCT07546162
- A Trial to Evaluate the Efficacy and Safety of SHR-1918 in Patients With HyperlipidemiaRecruitingNCT07230730Phase 31 country
- Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation StudyRecruitingNCT07685639Not applicable1 country
- Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk FactorsNot yet recruitingNCT07117695Not applicable1 country
- Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic RiskNot yet recruitingNCT07806279Phase 31 country
- Investigating the Combined Effects of Protein, Blueberries, and Exercise on Cardiovascular Health and Frailty in Older Nova ScotiansRecruitingNCT06693271Not applicable1 country
- Preventative Screening and Health Coaching in a Food Insecure PopulationRecruitingNCT06907524Not applicable1 country
- Icosapent Ethyl for High-Risk Coronary Plaques Assessed by 18F-NaF PET/CTNot yet recruitingNCT07762755Phase 41 country
- A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-236A and AD-236BNot yet recruitingNCT07730567Phase 11 country
- Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial HypercholesterolemiaRecruitingNCT06597006Phase 311 countries
- A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAL0167 in Healthy ParticipantsNot yet recruitingNCT07722299Phase 11 country
- Bacillus Subtilis and Enterococcus Faecium Probiotic Plus Lipid-Lowering Therapy for Hypertriglyceridemic Acute Pancreatitis: A Prospective RCTRecruitingNCT07720232Phase 41 country
- Tafolecimab in Hyperlipidemia: A Study of Different Dosing IntervalsNot yet recruitingNCT077120421 country
- Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" FoodRecruitingNCT06988462Not applicable1 country
- A Phase III Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe HypertriglyceridemiaNot yet recruitingNCT07693777Phase 31 country
- Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer SurvivorsEnrolling by invitationNCT06834204Not applicable1 country
- Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose ToleranceRecruitingNCT06684106Not applicable1 country
- Management Strategy of 1L Lorlatinib With Hyperlipidemia in Stage IIIB-IV ALK Positive NSCLCNot yet recruitingNCT076745241 country
- Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With HyperlipidemiaRecruitingNCT07662330Not applicable1 country
- A Clinical Study to Evaluate the Efficacy and Safety of Bempedoic AcidNot yet recruitingNCT07623915Phase 3
- Regional Innovation in Chronic Disease and Elderly CareRecruitingNCT075780901 country
- Social Needs Screening and Chronic Diseases Study (WE CARE)RecruitingNCT06903897Not applicable1 country
- Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans StudyNot yet recruitingNCT07592858Phase 21 country
- Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial HypercholesterolemiaRecruitingNCT06597019Phase 323 countries
- New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular DiseasesRecruitingNCT07588256Not applicable1 country
- Changes in Plaque Characteristics After Short-term Statin Therapy as Assessed With Coronary CTRecruitingNCT06603363Not applicable1 country
- Effect of Smartphone Application (MED-AD) on Medication Adherence Among Patients With Cardiovascular Disease in OmanEnrolling by invitationNCT06951451Not applicable1 country
- First-in-Human Study of ISH0688: Safety, Tolerability, Pharmacokinetics, and PharmacodynamicsNot yet recruitingNCT07505043Phase 11 country
- Chronic Kidney Disease and Metabolic Disorders in the ElderlyNot yet recruitingNCT074945261 country
- Mechanism of Ketogenic Diet-Induced HypercholesterolemiaRecruitingNCT06894004Not applicable1 country
- Penn Medicine Healthy HeartRecruitingNCT06062394Not applicable1 country
- Using a Telehealth and Shared Decision-Making Model to Address Preventative Medicine Strategies Among Communities in LouisianaRecruitingNCT05676970Not applicable1 country
- Imaging the Pathogenesis of Cerebral Small Vessel DiseaseRecruitingNCT057033861 country