Drug
Hydroxychloroquine clinical trials
Also written Plaquenil.
- studies test it
- 337
- open now
- 40
- in phase 3
- 95
- first study started
- 2002
Keep track of what changes. Save the Hydroxychloroquine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
337 studies that test it; most in 2020 (143)
| Year | Studies |
|---|---|
| 2002 | 2 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 4 |
| 2008 | 8 |
| 2009 | 6 |
| 2010 | 10 |
| 2011 | 14 |
| 2012 | 8 |
| 2013 | 8 |
| 2014 | 8 |
| 2015 | 8 |
| 2016 | 12 |
| 2017 | 15 |
| 2018 | 10 |
| 2019 | 10 |
| 2020 | 143 |
| 2021 | 25 |
| 2022 | 10 |
| 2023 | 4 |
| 2024 | 13 |
| 2025 | 5 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 11
- Phase 1
- 65
- Phase 2
- 150
- Phase 3
- 95
- Phase 4
- 38
- No phase
- 32
What it is tested for
Each study’s main condition, where its own words name it.
- COVID-19
- 119
Who runs them
Industry 16 · Other 321
Abramson Cancer Center at Penn Medicine (15) · Rutgers, The State University of New Jersey (8) · Assistance Publique - Hôpitaux de Paris (7) · NYU Langone Health (5) · University of Utah (4) · Assiut University (4) · National Cancer Institute (NCI) (3) · M.D. Anderson Cancer Center (3)
Often tested with
Tested in the same studies.
Azithromycin (35) · Lopinavir-ritonavir drug combination (9) · Remdesivir (8) · Etanercept (8) · Sulfasalazine (8) · Leflunomide (8) · Chloroquine (8) · Methotrexate (7)
Studies
Open first, then newest update. How each study uses Hydroxychloroquine is read from its arms, and is right about nine times in ten.
Testing it · 337
- Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing LossRecruitingPhase 2Chang Gung Memorial HospitalNCT06467526Written as Hydroxychloroquine
- Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN StudyRecruitingPhase 2Centre Hospitalier Universitaire de Saint EtienneNCT06350630Written as Hydroxychloroquine Oral Tablet
- ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months.Not yet recruitingPhase 3Starship Child Health, Te Toka Tumai AucklandNCT07830108Written as Hydroxychloroquine (HCQ)
- Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-AbRecruitingNot applicableSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT06652113Written as hydroxychloroquine and levothyroxine
- Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene VariantsNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT07443436Written as Hydroxychloroquine 400 mg/day
- Pilot Study of Hydroxychloroquine for the Treatment of AIMSSNot yet recruitingPhase 2Indiana UniversityNCT07825454Written as Hydroxychloroquine Sulfate (HCQ)
- Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary SarcoidosisRecruitingPhase 4Hospices Civils de LyonNCT05841758Written as Hydroxychloroquine
- Hydrochloroquinine & Decitabine With Venetoclax in AMLNot yet recruitingPhase 1Rutgers, The State University of New JerseyNCT07814339Written as Hydroxychloroquine
- The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for PreeclampsiaRecruitingPhase 3Yoo-min KimNCT05287321Written as Hydroxychloroquine
- Effects of Stopping Hydroxychloroquine in Elderly Lupus DiseaseRecruitingPhase 3NYU Langone HealthNCT05799378Written as Hydroxychloroquine
- Tunlametinib in Combination With Pucotenlimab and Hydroxychloroquine in NRAS Mutant MelanomaRecruitingPhase 2Sun Yat-sen UniversityNCT07750067Written as Hydroxychloroquine (HC)
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingPhase 2NYU Langone HealthNCT07138898Written as Hydroxychloroquine
- Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingPhase 3University of NebraskaNCT03414502Written as Hydroxychloroquine
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingPhase 4University of California, San FranciscoNCT07352566Written as Hydroxychloroquine
- ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast CancerRecruitingPhase 2Abramson Cancer Center at Penn MedicineNCT04523857Written as Hydroxychloroquine
- COAST Therapy in Advanced Solid Tumors and Prostate CancerRecruitingPhase 1/2Medical University of South CarolinaNCT05036226Written as Hydroxychloroquine, Metformin, Sirolimus
- Randomised Evaluation of COVID-19 TherapyRecruitingPhase 3University of OxfordNCT04381936Written as Hydroxychloroquine
- Neoadjuvant mFOLFIRINOX With Perioperative Oral Hydroxychloroquine in Resectable Pancreatic AdenocarcinomaRecruitingPhase 1/2West Virginia UniversityNCT04911816Written as Hydroxychloroquine sulfate
- Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular CarcinomaRecruitingPhase 1/2VA Office of Research and DevelopmentNCT05842174Written as Hydroxychloroquine
- Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic CausesRecruitingEarly Phase 1Children's Hospital of Fudan UniversityNCT04532346Written as Hydroxychloroquine
See all 337 studies that test Hydroxychloroquine →
Given in every arm · 38 — Hydroxychloroquine is usual care beside what is tested
- Doxycycline Boosted Therapy in Lyme Borreliosis: DoBo Study.Not yet recruitingPhase 4Radboud University Medical CenterNCT07230028Written as Hydroxychloroquin
- Rituximab Combining With Low-Dose Mycophenolate Mofetil on Proliferative Lupus Nephritis in ChildrenNot yet recruitingNot applicableNanfang Hospital, Southern Medical UniversityNCT07675291Written as Hydroxychloroquine (HCQ)
- Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE PatientsRecruitingPhase 4Fen LiNCT05666336Written as Hydroxychloroquine
- CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid TumorsRecruitingPhase 2Northwestern UniversityNCT05733000Written as Hydroxychloroquine
- A Study of Nivolumab and Hydroxychloroquine or Nivolumab/Ipilimumab and Hydroxychloroquine in Advanced MelanomaActive, not recruitingPhase 1/2Ravi Amaravadi, MDNCT04464759Written as Hydroxychloroquine
- A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF AberrationActive, not recruitingPhase 1/2Pediatric Brain Tumor ConsortiumNCT04201457Written as Hydroxychloroquine
- The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months TreatmentCompletedPhase 4Qilu Hospital of Shandong UniversityNCT03855007Written as HCQ
- Modulation of Autophagy in Patients With Advanced/Recurrent Non-small Cell Lung Cancer - Phase IICompletedPhase 2Rutgers, The State University of New JerseyNCT01649947Written as Hydroxychloroquine
- Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid ArthritisCompletedPhase 4SanofiNCT03449758Written as Hydroxychloroquine
- Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19CompletedPhase 3Tanta UniversityNCT04447534Written as Chloroquine or hydroxychloroquine
- Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLETerminatedPhase 3Chinese SLE Treatment And Research GroupNCT02444728Written as Hydroxychloroquine
- Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19Status unknownNot applicableGrupo de Investigación Clínica en Oncología RadioterapiaNCT04380818Written as Hydroxychloroquine Sulfate
- Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate MonotherapyTerminatedPhase 3Jawaharlal Institute of Postgraduate Medical Education & ResearchNCT02930343Written as Hydroxychloroquine
- Baricitinib, Placebo and Antiviral Therapy for the Treatment of Patients With Moderate and Severe COVID-19TerminatedPhase 2University of Southern CaliforniaNCT04373044Written as Hydroxychloroquine
- Clinical Trial of the Use of Tocilizumab for Treatment of SARS-CoV-2 Infection (COVID-19)Status unknownPhase 2Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauNCT04332094Written as Hydroxychloroquine
- A Study of Combination Therapies to Treat COVID-19 InfectionWithdrawnPhase 2ProgenaBiomeNCT04459702Written as hydroxychloroquine
- Hydroxychloroquine vs Nitazoxanide in Patients With COVID-19TerminatedPhase 4Hugo Mendieta ZeronNCT04341493Written as Hydroxychloroquine
- Sirolimus or Vorinostat and Hydroxychloroquine in Advanced CancerCompletedPhase 1M.D. Anderson Cancer CenterNCT01266057Written as Hydroxychloroquine
- The (HD)IVACOV Trial (The High-Dose IVermectin Against COVID-19 Trial)Status unknownPhase 2/3Corpometria InstituteNCT04712279Written as Hydroxychloroquine
- Combination Therapy With Camostat Mesilate + Hydroxychloroquine for COVID-19WithdrawnPhase 4Heinrich-Heine University, DuesseldorfNCT04338906Written as Hydroxychloroquine
Showing 20 of 38.
As the comparator · 15 — what is tested is compared with Hydroxychloroquine
- A Multicentre, Randomised, Double-blind, Positive-control Clinical Trial Evaluating Dihydroartemisinin Tablets for the Treatment of Discoid Lupus ErythematosusNot yet recruitingPhase 2Kunming Pharmaceuticals, Inc.NCT07557927Written as Hydroxychloroquine tablets
- The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic RosaceaRecruitingNot applicableThe Fourth Affiliated Hospital of Zhejiang University School of MedicineNCT07343635Written as Hydroxychloroquine
- Therapeutic Effect of Upadacitinib in Primary Sjögren's SyndromeNot yet recruitingPhase 2Peking University People's HospitalNCT06862284Written as Hydroxychloroquine (HCQ)
- The Efficacy and Safety of Iguratimod (IGU) in the Treatment of Primary Sjögren's SyndromeRecruitingPhase 4Second Affiliated Hospital, Zhejiang University, School of MedicineNCT04981145Written as Hydroxychloroquine Sulfate Tablets
- Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid ArthritisTerminatedPhase 2Incannex Healthcare LtdNCT05942911Written as Hydroxychloroquine
- Efficacy and Safety of Baricitinib in Sjogren's SyndromeCompletedPhase 2Peking Union Medical College HospitalNCT05016297Written as Hydroxychloroquine
- Efficacy and Safety of Hydroxychloroquine and Favipiravir in the Treatment of Mild to Moderate COVID-19Status unknownPhase 3Ministry of Health, TurkeyNCT04411433Written as Hydroxychloroquine
- Safety and Efficacy of Doxycycline and Rivaroxaban in COVID-19Status unknownPhase 4Yaounde Central HospitalNCT04715295Written as Hydroxychloroquine and Azithromycin
- Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 PandemicCompletedNot applicableBenha UniversityNCT04668469Written as Hydroxychloroquine
- Treatment of Pregnancy RAStatus unknownNot applicableRenJi HospitalNCT04569890Written as Hydroxychloroquine
- Phytomedicines Versus Hydroxychloroquine as an Add on Therapy to Azythromycin in Asymptomatic Covid-19 PatientsStatus unknownPhase 2Institute for Research and Development of Medicinal and Food Plants of GuineaNCT04501965Written as Hydroxychloroquine/Azithromycine
- Comparison of Lopinavir/Ritonavir or Hydroxychloroquine in Patients With Mild Coronavirus Disease (COVID-19)TerminatedPhase 2Asan Medical CenterNCT04307693Written as Hydroxychloroquine sulfate
- Levamisole and Isoprinosine in the Treatment of COVID19: A Proposed Therapeutic TrialStatus unknownPhase 3Cairo UniversityNCT04383717Written as Azithromycin and hydroxychloroquine
- Very Early Versus Delayed Etanercept in Patients With RACompletedPhase 4University of LeedsNCT02433184Written as Hydroxychloroquine
- Targeted Treatment Early With Etanercept + Methotrexate vs.T2T Care for DMARD-naïve Early RA Patients Based on naïve T-cell StratificationStatus unknownPhase 4University of LeedsNCT03813771Written as Hydroxychloroquine
Codes
What other systems call Hydroxychloroquine · ClinicalTrials.gg INT007632
- MeSH (NLM) D006886HydroxychloroquineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 4QWG6N8QKHHYDROXYCHLOROQUINEConfirmed FDA, NLM, Wikidata
- RxNorm 5521Confirmed FDA, Wikidata
- Wikidata Q421094hydroxychloroquineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C557HydroxychloroquineOne source FDA
- DrugBank DB01611One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D006886 | Hydroxychloroquine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 4QWG6N8QKH | HYDROXYCHLOROQUINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5521 | — | Confirmed FDA, Wikidata |
| Wikidata | Q421094 | hydroxychloroquine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C557 | Hydroxychloroquine | One source FDA |
| DrugBank | DB01611 | — | One source Wikidata |
Also registered as hydroxychloroquine sulfate (UNII 8Q2869CNVH · RxNorm 153972).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.