Pancreatic Neoplasms clinical trials
The registry lists 3,896 studies for Pancreatic Neoplasms across more than 10 countries. 1,006 are recruiting or about to start. 2,769 of them are mainly about Pancreatic Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 11 narrower conditions too, such as Adenoma, Islet Cell: 4,169 studies, 1,080 open.
ClinicalTrials.gov finds 5,126 studies for Pancreatic Neoplasms. How that becomes 3,891 here
This page counts the studies the registry files under Pancreatic Neoplasms, and those it files under no condition that list Pancreatic Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 5,126Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −223Filed under a narrower condition, counted on its own pageAdenoma, Islet Cell 93 · Insulinoma 38 · Carcinoma, Pancreatic Ductal 32 · Pancreatic Intraductal Neoplasms 18 · Somatostatinoma 15 · Pancreatic cancer, adult 8 · 4 more
- −57List Pancreatic Neoplasms as a condition, but the registry did not file them under itMost often written as “Pancreatic Cancer Resectable” (9), “Pancreatic Cancer Metastatic” (8), and “Pancreatic Cancer Non-resectable” (7). The registry filed them under other conditions only, most often Colorectal Neoplasms (9) and Neoplasms (8).
- −955Match it another way282 name it in the title, 9 in a keyword, and 664 by a synonym or other text the search reads.
- 3,891The count on this page212 of them list Pancreatic Neoplasms in their own words; the registry filed them under no condition.
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Enrollment: 300 → 450 participants
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Status
Who runs them
National Cancer Institute (NCI) (114) · M.D. Anderson Cancer Center (66) · Fudan University (54) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (52) · Memorial Sloan Kettering Cancer Center (50) · Mayo Clinic (40) · Washington University School of Medicine (34) · Changhai Hospital (34)
What is being tested here
Drugs under test in Pancreatic Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 56 open · Antimetabolites 38 open · Antimitotic agents 23 open · Tyrosine kinase inhibitors (TKIs) 20 open · PARP inhibitors 7 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer · Phase 3 · Fudan University
- Dec 2026Safety and Efficacy of Immuncell-LC With Gemcitabine in Resectable Pancreatic Cancer · Phase 3 · GC Cell Corporation
- Dec 2026Clinical Study of Tumor Treating Fields Combined with Gemcitabine and Albumin-bound Paclitaxel in the First-line Treatment of Locally Advanced Pancreatic Cancer · Phase 3 · Jiangsu Healthy Life Innovation Medical Technology Co., Ltd
- Dec 2026Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy? · Phase 3 · Case Comprehensive Cancer Center
- Jan 2027Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer · Phase 3 · Erasmus Medical Center
- Mar 2027HR070803 in Combination With Oxaliplatin, 5-fluorouracil/LV Versus GX as Adjuvant Therapy for Pancreatic Cancer · Phase 3 · Fudan University
- May 2027A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer · Phase 3 · Akeso
- May 2027Nimotuzumab Combined With GX as Postoperative Adjuvant Therapy in Pancreatic Cancer · Phase 3 · Tianjin Medical University Cancer Institute and Hospital
- May 2027Study of XNW28012 in Subjects With Metastatic Pancreatic Cancer Who Received Prior Systemic Therapy · Phase 3 · Evopoint Biosciences Inc.
- Jun 2027A Study Comparing MRG004A Plus Best Supportive Care Versus Placebo and Best Supportive Care in the Treatment of Patients With Advanced Pancreatic Cancer · Phase 3 · Lepu Biopharma Co., Ltd.
Who these studies take
Of the 745 Pancreatic Neoplasms studies recruiting now, 478 (64%) set no upper age limit and 151 (20%) stop at 75 or younger. 40 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 59 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 29 (4%) | 29 (4%) |
| 18 | 691 (93%) | 691 (93%) |
| 30 | 726 (97%) | 726 (97%) |
| 40 | 733 (98%) | 733 (98%) |
| 50 | 741 (99%) | 741 (99%) |
| 65 | 743 (100%) | 743 (100%) |
| 75 | 719 (97%) | 719 (97%) |
| 85 | 535 (72%) | 535 (72%) |
Across all 3,896 studies, recruiting or not: 14% stop at 75 or younger and 1% at 65; 5% take children; <1% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pancreatic Neoplasms studies take
Of 393 phase 2 interventional studies under Pancreatic Neoplasms, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 45 mo32–67 · 379 studies | 44 mo31–62 · 171 studies | 46 mo33–74 · 208 studies |
| Phase 1/2 | 51 mo36–89 · 209 studies | 47 mo34–88 · 115 studies | 61 mo38–95 · 94 studies |
| Phase 2 | 57 mo35–80 · 393 studies | 36 mo26–68 · 69 studies | 60 mo36–80 · 324 studies |
| Phase 3 | 58 mo36–77 · 84 studies | — | 68 mo39–79 · 46 studies |
| Interventional, no phase | 44 mo26–75 · 430 studies | — | 45 mo26–75 · 403 studies |
| Observational | 60 mo34–182 · 352 studies | — | 74 mo34–182 · 318 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting9
- Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic CancerNov 9, 2026NCT07325214
- GnP Combined With SHR-1701 and Apatinib as First-Line Treatment for Metastatic PDACNov 9, 2026NCT07802184
- Lm-LLO-TT and Gemcitabine in Unresectable Pancreatic Ductal AdenocarcinomaNov 6, 2026NCT07828236
- Feasibility and Effectiveness of Three-day Discharge After Distal PancreatectomyNov 5, 2026NCT07095621
- A Study of MGC030 in Participants With Advanced Solid TumorsOct 30, 2026NCT07822399
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- First in Human Study of SNV1521 With a RAS Inhibitor for People With Advanced Pancreatic CancerOct 27, 2026NCT07756281
- An Open-Label, Multicenter, Phase IB/II Clinical Study of HRS-7172 in Combination With Antitumor Therapy in Participants With Solid TumorsOct 26, 2026NCT07806058
- Reach and Engagement of GENetic Education, Risk Assessment, and TEsting Feasibility TrialOct 22, 2026NCT07787156
- Evaluating Intermittent Fasting In Individuals At High Risk ForPancreatic Cancer Undergoing ScreeningOct 14, 2026NCT07513116
Results posted7
- Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic CancerNov 4, 2026NCT03073785
- Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.Nov 4, 2026NCT04753879
- Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to SurgeryNov 3, 2026NCT05111353
- Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic CancerNov 3, 2026NCT05911243
- ZN-c3 + Gemcitabine in Pancreatic CancerOct 27, 2026NCT06015659
Show 2 moreShow fewer
Stopped5
- EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)TerminatedNov 6, 2026NCT05723107
- huCART-meso + VCN-01 in Pancreatic and Ovarian CancerTerminatedOct 29, 2026NCT05057715
- ZN-c3 + Gemcitabine in Pancreatic CancerTerminatedOct 27, 2026NCT06015659
- Pilot Study of Pancreatic Cancer ScreeningTerminatedOct 26, 2026NCT05058846
- Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic CancerSuspendedOct 20, 2026NCT04172532
Newly registered17
- A Multicenter, Prospective Single-arm Study of Multimodal Thermal Therapy Combined With Toripalimab and AG Chemotherapy in the Treatment of Advanced Pancreatic CancerNov 10, 2026NCT07928362
- Study of MC001 in Patients With Advanced Solid TumoursNov 10, 2026NCT07929961
- Association of Psychological Distress With Clinical Outcomes in Patients With Digestive System CancersNov 9, 2026NCT07924189
- Endoscopic Ultrasound Shear Wave Elastography in Solid Pancreatic LesionsNov 9, 2026NCT07924540
- Artificial Intelligence-Assisted 4D Dynamic Long-Axial PET Imaging for the Detection of Early Pancreatic Cancer LesionsNov 9, 2026NCT07925125
Show 12 moreShow fewer
- A Study of MC001 in Patients With Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) and Other Folate Receptor Alpha (FRα)-Expressing Solid TumorsNov 2, 2026NCT07909356
- The Use of Contrast Enhanced Ultrasound (CEUS) In Post-Surgical Pancreatic Cancer Patients to Evaluate Local Disease RecurrenceNov 2, 2026NCT07910383
- Development and Utilization of an Integrated Clinical Genomic DatabaseNov 2, 2026NCT07911267
- A Study to Assess the Effect of Itraconazole on the Pharmacokinetics of HRS-4642 Following Intravenous Infusion in Healthy ParticipantsOct 30, 2026NCT07906691
- A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.Oct 29, 2026NCT07903415
- A Study of Perioperative Navlimetostat Combined With Modified FOLFIRINOX in Patients With MTAP-Deleted Pancreatic CancerOct 29, 2026NCT07905131
- Daraxonrasib in Resectable PDACOct 27, 2026NCT07898813
- A Study of Standard of Care Drugs With or Without Ivermectin for Daraxonrasib-Induced Skin Toxicity in People With Pancreatic CancerOct 26, 2026NCT07895498
- Becotatug Vedotin Plus Anti-PD-1 and S-1 in Patients With EGFR-Positive Advanced Pancreatic Cancer Who Have Failed at Least One Line of Standard TherapyOct 23, 2026NCT07892573
- Diagnostic Utility of Protein Biomarkers in Pancreatic Ductal AdenocarcinomaOct 15, 2026NCT07875582
- Phase 1 Study of NW-301V TCR-T Cells in Advanced Solid Tumors With KRAS G12V MutationOct 15, 2026NCT07875920
- Histotripsy x Pancreatic CancerOct 14, 2026NCT07873606
Studies
Recruiting first, then most recently updated. Showing 50 of 3,896. Browse all 3,896 → or search them.
- APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 MutationRecruitingNCT04858334Phase 23 countries
- A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) MutationRecruitingNCT07458347Phase 11 country
- Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic CancerRecruitingNCT01174121Phase 21 country
- Laparoscopic PancreaticoduodenectomyRecruitingNCT07009119Not applicable1 country
- Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid TumorsRecruitingNCT05053971Phase 1/21 country
- High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver MalignanciesRecruitingNCT05053555Not applicable1 country
- Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 GeneRecruitingNCT05372614Phase 11 country
- Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesRecruitingNCT04907643Not applicable1 country
- Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaRecruitingNCT019505721 country
- Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic CancerRecruitingNCT03492671Phase 21 country
- Study of MC001 in Patients With Advanced Solid TumoursNot yet recruitingNCT07929961Phase 11 country
- EUS-CPN With and Without BupivacaineRecruitingNCT04951804Not applicable1 country
- A Multicenter, Prospective Single-arm Study of Multimodal Thermal Therapy Combined With Toripalimab and AG Chemotherapy in the Treatment of Advanced Pancreatic CancerNot yet recruitingNCT07928362Not applicable1 country
- Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing PancreatectomyNot yet recruitingNCT07608458Not applicable1 country
- A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsRecruitingNCT07020221Phase 1/24 countries
- Predictive Risk Factors for Pancreatic Fistula After PancreaticoduodenectomyRecruitingNCT07022015Not applicable1 country
- Artificial Intelligence-Assisted 4D Dynamic Long-Axial PET Imaging for the Detection of Early Pancreatic Cancer LesionsRecruitingNCT079251251 country
- Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic CancerRecruitingNCT07325214Not applicable2 countries
- GnP Combined With SHR-1701 and Apatinib as First-Line Treatment for Metastatic PDACRecruitingNCT07802184Phase 1/21 country
- Metarrestin (ML-246) in Subjects With Metastatic Solid TumorsRecruitingNCT04222413Phase 11 country
- Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal AdenocarcinomaRecruitingNCT06141031Phase 11 country
- Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Pancreatic CancerNot yet recruitingNCT075284301 country
- A Single-Arm Study of Nimotuzumab Combined With NALIRIFOX as First-Line Treatment for Pancreatic CancerEnrolling by invitationNCT07920731Phase 21 country
- A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic CancerRecruitingNCT07644559Phase 24 countries
- Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic FistulaRecruitingNCT06807437Phase 31 country
- CREO - Microwave Ablation Feasibility StudyRecruitingNCT07817147Not applicable1 country
- The Vanguard Study: Testing a New Way to Screen for CancerRecruitingNCT06995898Not applicable1 country
- Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )RecruitingNCT07621718Phase 35 countries
- Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic AdenocarcinomaRecruitingNCT07562152Phase 39 countries
- Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic AdenocarcinomaRecruitingNCT07805954Phase 31 country
- Lm-LLO-TT and Gemcitabine in Unresectable Pancreatic Ductal AdenocarcinomaRecruitingNCT07828236Phase 11 country
- A Decision Support Tool for Pancreatic Cancer Screening -Aim 2Not yet recruitingNCT07808671Not applicable1 country
- Feasibility and Effectiveness of Three-day Discharge After Distal PancreatectomyRecruitingNCT070956211 country
- Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 11 country
- A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid TumorsRecruitingNCT07090499Phase 16 countries
- INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE StudyRecruitingNCT07671937Not applicable1 country
- Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic CancerRecruitingNCT05132504Phase 21 country
- A 2-part Phase 1/2 Open-label Trial on ODM-212RecruitingNCT07563738Phase 1/27 countries
- A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid TumorsRecruitingNCT06465069Phase 18 countries
- Distance-Based Exercise to Preserve Function and Prevent DisabilityRecruitingNCT07059884Not applicable1 country
- A Study of GKL-006 Injection in Patients With Advanced Pancreatic CancerRecruitingNCT07777211Phase 1/21 country
- A Study of Sofe-M in Participants With Selected Advanced Solid TumorsRecruitingNCT06400472Phase 17 countries
- VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaRecruitingNCT03556228Phase 1/22 countries
- A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)RecruitingNCT07492680Phase 213 countries
- A Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsRecruitingNCT06695845Phase 24 countries
- A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)RecruitingNCT06760819Phase 211 countries
- cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT053668811 country
- A Study of MC001 in Patients With Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) and Other Folate Receptor Alpha (FRα)-Expressing Solid TumorsNot yet recruitingNCT07909356Phase 11 country
- A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.RecruitingNCT07903415Phase 11 country
- A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic CancerRecruitingNCT07409272Phase 311 countries