Drug
Chloroquine clinical trials
Also written Aralen and Nivaquine®.
- studies test it
- 93
- open now
- 6
- in phase 3
- 25
- first study started
- 1993
Keep track of what changes. Save the Chloroquine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Studies by the year they started
93 studies that test it; most in 2014 (10)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 2001 | 2 |
| 2002 | 2 |
| 2003 | 5 |
| 2004 | 6 |
| 2005 | 3 |
| 2006 | 5 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 9 |
| 2010 | 2 |
| 2011 | 5 |
| 2012 | 6 |
| 2013 | 1 |
| 2014 | 10 |
| 2015 | 5 |
| 2016 | 2 |
| 2017 | 2 |
| 2018 | 1 |
| 2020 | 10 |
| 2021 | 1 |
| 2022 | 5 |
| 2023 | 3 |
| 2024 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 16
- Phase 2
- 27
- Phase 3
- 25
- Phase 4
- 23
- No phase
- 14
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 22
Who runs them
Industry 14 · Other 79
Pfizer (10) · London School of Hygiene and Tropical Medicine (7) · University of Oxford (6) · Menzies School of Health Research (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · GlaxoSmithKline (4) · University of Maryland, Baltimore (3) · Maastricht Radiation Oncology (3)
Often tested with
Tested in the same studies.
Fanasil, pyrimethamine drug combination (11) · Azithromycin (11) · Primaquine (10) · Artemether, Lumefantrine Drug Combination (8) · Hydroxychloroquine (8) · Artenimol (6) · Piperaquine (6) · Tafenoquine (5)
Studies
Open first, then newest update. How each study uses Chloroquine is read from its arms, and is right about nine times in ten.
Testing it · 93
- Southeast Asia Dose Optimization of TafenoquineRecruitingPhase 4University of OxfordNCT04704999Written as Chloroquine
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingPhase 4University of California, San FranciscoNCT07352566Written as Chloroquine
- Tafenoquine Combinations for Improved Radical Cure Efficacy of Plasmodium VivaxNot yet recruitingNot applicableWalter Reed Army Institute of Research (WRAIR)NCT07533136Written as Chloroquine (CQ)
- ACT vs CQ With Tafenoquine for P. Vivax Mono-infectionRecruitingPhase 4Shoklo Malaria Research UnitNCT05788094Written as Chloroquine plus Tafenoquine (450 mg adult dose)
- Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis TherapyRecruitingPhase 1University of ZurichNCT05443178Written as Nivaquine ® (Chloroquine)
- Hydroxychloroquine Combined With Gemcitabine in the Treatment of Advanced Non-small Cell Lung CancerNot yet recruitingPhase 2Henan Cancer HospitalNCT05647330Written as Hydroxychloroquine Combined With Gemcitabine
- Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, MalawiCompletedPhase 4Liverpool School of Tropical MedicineNCT06083688Written as Chloroquine
- Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese ShieldCompletedNot applicableCentre Hospitalier de CayenneNCT05540470Written as PART
- Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant WomenCompletedPhase 3London School of Hygiene and Tropical MedicineNCT00131703Written as Chloroquine
- Saved From COVID-19 - Chloroquine (CQ) Prophylaxis for Health Care Workers at Risk for COVIDTerminatedPhase 2Columbia UniversityNCT04349371Written as Chloroquine
- Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed GlioblastomaTerminatedPhase 1Barbara Ann Karmanos Cancer InstituteNCT04397679Written as Chloroquine
- Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 InfectionTerminatedPhase 3Washington University School of MedicineNCT04341727Written as Chloroquine Sulfate
- A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east BangladeshCompletedPhase 4Menzies School of Health ResearchNCT02389374Written as chloroquine
- Study of Whole-brain Irradiation With Chloroquine for Brain MetastasesTerminatedPhase 2Instituto Nacional de Cancerologia de MexicoNCT01894633Written as Chloroquine
- The Addition of Chloroquine to Chemoradiation for Glioblastoma,WithdrawnPhase 2Maastricht Radiation OncologyNCT02432417Written as Chloroquine
- Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium VivaxCompletedPhase 4Dinka DugassaNCT06044805Written as Chloroquine
- Comparing Chemoprevention Drugs for School-based Malaria ControlCompletedPhase 4University of Maryland, BaltimoreNCT05980156Written as Chloroquine
- Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare SettingCompletedNot applicableUniversity of OxfordNCT04303507Written as Chloroquine or Hydroxychloroquine
- Comparing Chemoprevention Approaches for School-based Malaria ControlCompletedPhase 4University of Maryland, BaltimoreNCT05244954Written as Chloroquine
- Daily Trimethoprim-sulfamethoxazole or Weekly Chloroquine Among Adults on ART in MalawiCompletedNot applicableUniversity of Maryland, BaltimoreNCT01650558Written as Chloroquine (CQ) prophylaxis
See all 93 studies that test Chloroquine →
Given in every arm · 15 — Chloroquine is usual care beside what is tested
- An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and OlderRecruitingPhase 3GlaxoSmithKlineNCT06666491Written as Chloroquine
- Tafenoquine Drug Levels in Small ChildrenNot yet recruitingPhase 2University of OxfordNCT07835321Written as Chloroquine
- Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient PatientsCompletedPhase 2Fundação de Medicina Tropical Dr. Heitor Vieira DouradoNCT03529396Written as Chloroquine
- Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid ArthritisCompletedPhase 4SanofiNCT03449758Written as Chloroquine
- Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19CompletedPhase 3Tanta UniversityNCT04447534Written as Chloroquine or hydroxychloroquine
- Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.CompletedPhase 4State University of New York - Upstate Medical UniversityNCT02564471Written as Chloroquine
- A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) MalariaCompletedPhase 2GlaxoSmithKlineNCT02563496Written as Chloroquine
- G6PD Assessment Before Primaquine for Radical Treatment of Vivax MalariaCompletedPhase 4University of OxfordNCT02876549Written as Chloroquine
- A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid ArthritisCompletedPhase 3Hoffmann-La RocheNCT01941095Written as Chloroquine
- Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax MalariaCompletedPhase 3GlaxoSmithKlineNCT02216123Written as Chloroquine
- Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...CompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT02511054Written as Chloroquine (CQ)
- Vascular Function Intervention Trial in Sickle Cell DiseaseStatus unknownPhase 2/3London School of Hygiene and Tropical MedicineNCT01718054Written as Chloroquine
- Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax InfectionCompletedPhase 2/3Oswaldo Cruz FoundationNCT02691910Written as Chloroquine
- Chloroquine Alone or in Combination for Malaria in Children in MalawiCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00379821Written as Chloroquine
- Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and MorbidityCompletedPhase 4Papua New Guinea Institute of Medical ResearchNCT02143934Written as Chloroquine
As the comparator · 18 — what is tested is compared with Chloroquine
- This is a Clinical Study to Assess Whether the Combination of SJ733 and Tafenoquine Will be a Safe and Rapidly Acting Anti-malarial for the Radical Cure of P. Vivax MalariaNot yet recruitingPhase 2R. Kiplin GuyNCT07430592Written as CQ/TQ Placebo
- Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax MalariaTerminatedPhase 3Medicines for Malaria VentureNCT04368910Written as Chloroquine
- Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax MalariaCompletedPhase 3Medicines for Malaria VentureNCT00440999Written as Chloroquine
- Efficacy of Faviprevir in COVID-19 TreatmentCompletedPhase 2/3Tanta UniversityNCT04351295Written as Chloroquine
- PRophylaxis of Exposed COVID-19 Individuals With Mild Symptoms Using choloroquinE CompoundsTerminatedPhase 4Government of Punjab, Specialized Healthcare and Medical Education DepartmentNCT04351191Written as Chloroquine
- Post-Exposure Prophylaxis for Asymptomatic SARS-CoV-2 COVID-19 Patients With choloroquinE CompoundsTerminatedPhase 4Government of Punjab, Specialized Healthcare and Medical Education DepartmentNCT04346667Written as Chloroquine
- Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With ChloroquineCompletedPhase 1Tulane University Health Sciences CenterNCT00323375Written as Chloroquine (CQ) Treatment
- Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria ProphylaxisWithdrawnPhase 2U.S. Army Medical Research and Development CommandNCT03278808Written as Chloroquine (CQ)
- Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in AdultsTerminatedPhase 2U.S. Army Medical Research and Development CommandNCT01290601Written as Chloroquine + Primaquine
- Comparison Between 7 and 14 Day Primaquine Combined With Dihydroartemisinin-piperaquine or 3 Day Chloroquine Radical Cure of P. Vivax (BPD)CompletedPhase 3University of OxfordNCT01640574Written as Chloroquine
- Prednisone Plus Chloroquine for the Treatment of Hyper-reactive Malarial SplenomegalyWithdrawnPhase 3Lihir Medical CentreNCT01785979Written as Chloroquine
- Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax MalariaCompletedPhase 3SanofiNCT01378286Written as Chloroquine
- Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in ThailandStatus unknownPhase 4Mahidol UniversityNCT01662700Written as Chloroquine
- Pilot Human Study of Tinidazole Efficacy For Radical Cure Of Plasmodium VivaxCompletedPhase 2Walter Reed Army Institute of Research (WRAIR)NCT00811096Written as chloroquine
- Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Vivax in Pregnancy in Brazil (PAACT-PV)TerminatedPhase 4Centers for Disease Control and PreventionNCT01107145Written as Chloroquine
- New Approaches to Improve Coverage and Compliance of Antimalarial Treatment for Pregnant Women in Rural AfricaCompletedPhase 3Institute of Tropical Medicine, BelgiumNCT00730366Written as Chloroquine
- A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult SubjectsCompletedPhase 1PfizerNCT01100060Written as chloroquine (CQ)
- A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And ChloroquineCompletedPhase 1PfizerNCT00844207Written as Azithromycin and Chloroquine
Codes
What other systems call Chloroquine · ClinicalTrials.gg INT007200
- MeSH (NLM) D002738ChloroquineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 886U3H6UFFCHLOROQUINEConfirmed FDA, NLM, Wikidata
- RxNorm 2393Confirmed FDA, Wikidata
- Wikidata Q422438chloroquineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61671ChloroquineOne source FDA
- DrugBank DB00608One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002738 | Chloroquine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 886U3H6UFF | CHLOROQUINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2393 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422438 | chloroquine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61671 | Chloroquine | One source FDA |
| DrugBank | DB00608 | — | One source Wikidata |
Also registered as chloroquine sulfate (UNII OE48649K6N · RxNorm 203119).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.