Hydroxychloroquine: all 337 studies that test it

Page 1 of 4. Open to participants first (40), then studies with results posted, then the rest; newest registration first within each.

• ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months.Not yet recruitingNCT07830108Phase 3
• Pilot Study of Hydroxychloroquine for the Treatment of AIMSSNot yet recruitingNCT07825454Phase 2
• Hydrochloroquinine & Decitabine With Venetoclax in AMLNot yet recruitingNCT07814339Phase 1
• Tunlametinib in Combination With Pucotenlimab and Hydroxychloroquine in NRAS Mutant MelanomaRecruitingNCT07750067Phase 2
• AIPH-TB: AI-Optimised Pyrazinamide-Hydroxychloroquine vs Standard RIPE for Drug-Sensitive Pulmonary Tuberculosis - A Phase II RCTNot yet recruitingNCT07467252Phase 2
• Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene VariantsNot yet recruitingNCT07443436Phase 2
• Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
• Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 2
• Autophagy Maintenance (AUTOMAIN)RecruitingNCT06971744Phase 2
• Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral MucositisRecruitingNCT06939582Phase 1/2
• A Study to Evaluate Efficacy, Safety and Tolerability of Hydroxychloroquine in Subjects With Parkinson's DiseaseNot yet recruitingNCT06816810Phase 2
• Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy?RecruitingNCT06676384Phase 4
• Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-AbRecruitingNCT06652113Not applicable
• The Efficacy and Safety of HCQ Plus DEX in ANA Positive ITPRecruitingNCT06479317Not applicable
• The Efficacy and Safety of HCQ Plus Pred in ANA Positive ITPRecruitingNCT06479304Not applicable
• The Efficacy and Safety of HCQ Plus TPO-RA in ANA Positive ITPRecruitingNCT06479291Not applicable
• Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing LossRecruitingNCT06467526Phase 2
• HCQ in Resectable Localized Prostate CancerRecruitingNCT06408298Early Phase 1
• Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC PatientsRecruitingNCT06389201Not applicable
• Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN StudyRecruitingNCT06350630Phase 2
• HCQ+ADC vs ADC in the Treatment of Advanced Breast CancerRecruitingNCT06328387Phase 1/2
• Hydroxychloroquine in Type 2 Diabetes During PregnancyRecruitingNCT06319560Not applicable
• Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS MutationsRecruitingNCT06229340Phase 2
• The Effects of Hydroxychloroquine in Patients with Inflammatory CardiomyopathyRecruitingNCT05961202Phase 2/3
• Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular CarcinomaRecruitingNCT05842174Phase 1/2
• Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary SarcoidosisRecruitingNCT05841758Phase 4
• Effects of Stopping Hydroxychloroquine in Elderly Lupus DiseaseRecruitingNCT05799378Phase 3
• The Clinical Efficacy of Immunomodulators in RA PatientsRecruitingNCT05626348Phase 4
• The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for PreeclampsiaRecruitingNCT05287321Phase 3
• Hydroxychloroquine in Mild Graves' OrbitopathyRecruitingNCT05126147Phase 4
• New Clinical End-points in Patients With Primary Sjögren's SyndromeRecruitingNCT05113004Phase 2
• Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)RecruitingNCT05041907Phase 2
• COAST Therapy in Advanced Solid Tumors and Prostate CancerRecruitingNCT05036226Phase 1/2
• Neoadjuvant mFOLFIRINOX With Perioperative Oral Hydroxychloroquine in Resectable Pancreatic AdenocarcinomaRecruitingNCT04911816Phase 1/2
• Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic CausesRecruitingNCT04532346Early Phase 1
• ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast CancerRecruitingNCT04523857Phase 2
• Randomised Evaluation of COVID-19 TherapyRecruitingNCT04381936Phase 3
• Immune-Mediated Pathophysiology And Clinical Triage ProgramRecruitingNCT04354649Phase 2
• Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingNCT03414502Phase 3
• Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
• Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) MalignanciesTerminatedNCT05221320Phase 2Results posted
• Study of Paclitaxel Protein Bound + Gemcitabine + Cisplatin + Hydroxychloroquine as Treatment in Untreated Pancreas CancerCompletedNCT04669197Phase 2Results posted
• A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19TerminatedNCT04605588Phase 2Results posted
• Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).TerminatedNCT04566133Phase 2Results posted
• Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K MelanomaTerminatedNCT04527549Phase 2Results posted
• Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic CancerCompletedNCT04524702Phase 2Results posted
• Clearing the Fog: Is Hydroxychloroquine Effective in Reducing COVID-19 ProgressionCompletedNCT04491994Phase 3Results posted
• Non-comparative Trial of the Combination of HCQ and AZI in the Treatment of ICU PatientsTerminatedNCT04458948Phase 2Results posted
• Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19TerminatedNCT04435808Phase 1/2Results posted
• LY3214996 +/- HCQ in Pancreatic CancerCompletedNCT04386057Phase 2Results posted
• A Study of Hydroxychloroquine vs Placebo to Prevent COVID-19 Infection in Patients Receiving RadiotherapyTerminatedNCT04381988Phase 2Results posted
• Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 InfectionTerminatedNCT04372017Phase 3Results posted
• Treating COVID-19 With Hydroxychloroquine (TEACH)TerminatedNCT04369742Phase 2Results posted
• Hydroxychloroquine Monotherapy and in Combination With Azithromycin in Patients With Moderate and Severe COVID-19 DiseaseCompletedNCT04358081Phase 3Results posted
• Evaluating the Efficacy of Hydroxychloroquine and Azithromycin to Prevent Hospitalization or Death in Persons With COVID-19TerminatedNCT04358068Phase 2Results posted
• COVID-19 PrEP HCW HCQ StudyCompletedNCT04354870Phase 2Results posted
• Treatment for COVID-19 in High-Risk Adult OutpatientsTerminatedNCT04354428Phase 2/3Results posted
• Trial of Hydroxychloroquine In Covid-19 KineticsTerminatedNCT04353271Phase 2/3Results posted
• Hydroxychloroquine as Chemoprevention for COVID-19 for High Risk Healthcare WorkersCompletedNCT04345653Phase 2Results posted
• University of Utah COVID-19 Hydrochloroquine TrialCompletedNCT04342169Phase 2Results posted
• Hydroxychloroquine,Hydroxychloroquine,Azithromycin in the Treatment of SARS CoV-2 InfectionTerminatedNCT04341727Phase 3Results posted
• Randomized Comparison of Combination Azithromycin and Hydroxychloroquine vs. Hydroxychloroquine Alone for the Treatment of Confirmed COVID-19TerminatedNCT04336332Phase 2Results posted
• Pragmatic Factorial Trial of Hydroxychloroquine, Azithromycin, or Both for Treatment of Severe SARS-CoV-2 InfectionTerminatedNCT04335552Phase 2Results posted
• Healthcare Worker Exposure Response and Outcomes of HydroxychloroquineCompletedNCT04334148Phase 3Results posted
• Hydroxychloroquine in the Prevention of COVID-19 Infection in Healthcare WorkersCompletedNCT04333225Phase 2Results posted
• Outcomes Related to COVID-19 Treated With Hydroxychloroquine Among In-patients With Symptomatic DiseaseCompletedNCT04332991Phase 3Results posted
• The PATCH Trial (Prevention And Treatment of COVID-19 With Hydroxychloroquine)TerminatedNCT04329923Phase 2Results posted
• Hydroxychloroquine vs. Azithromycin for Hospitalized Patients With Suspected or Confirmed COVID-19CompletedNCT04329832Phase 2Results posted
• Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)CompletedNCT04328961Phase 2/3Results posted
• Pre-exposure Prophylaxis for SARS-Coronavirus-2CompletedNCT04328467Phase 3Results posted
• Proactive Protection With Azithromycin and hydroxyChloroquine in Hospitalized Patients With COVID-19TerminatedNCT04322396Phase 2Results posted
• Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)TerminatedNCT04318444Phase 2/3Results posted
• Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2CompletedNCT04308668Phase 3Results posted
• Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced MalignanciesTerminatedNCT04214418Phase 1/2Results posted
• Hydroxychloroquine to Increase Tumor Suppressor PAR-4 Levels in Oligometastatic Prostate CancerCompletedNCT04011410Phase 2Results posted
• Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast CancerCompletedNCT03774472Phase 1/2Results posted
• Management of Cardiovascular Disease in Kidney Disease (MaCK) StudyCompletedNCT03636152Phase 2Results posted
• Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes MellitusTerminatedNCT03428945Phase 2Results posted
• Pre-Operative Trial (PGHA vs. PGH) for Resectable Pancreatic CancerTerminatedNCT03344172Phase 2Results posted
• Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAITCompletedNCT03283566Phase 2Results posted
• Hydroxychloroquine for the Treatment of Hidradenitis SuppurativaCompletedNCT03275870Phase 1/2Results posted
• To Determine the Safety of Regorafenib, Hydroxychloroquine, and Entinostat Metastatic Colorectal CancerCompletedNCT03215264Phase 1Results posted
• Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular CancerCompletedNCT03037437Phase 2Results posted
• CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast CancerActive, not recruitingNCT03032406Phase 2Results posted
• Study of Anti-Malarials in Incomplete Lupus ErythematosusCompletedNCT03030118Phase 2Results posted
• Hydroxychloroquine and Cognitive Function After SurgeryTerminatedNCT03025087Phase 4Results posted
• Hydroxychloroquine (HCQ) in Pediatric Interstitial Lung Disease (ILD)TerminatedNCT02615938Phase 2Results posted
• Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid ArthritisTerminatedNCT02603146Phase 2Results posted
• IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIACompletedNCT02451748Phase 4Results posted
• Treatments Against RA and Effect on FDG-PET/CTCompletedNCT02374021Phase 4Results posted
• Vorinostat Plus Hydroxychloroquine Versus Regorafenib in Colorectal CancerCompletedNCT02316340Phase 2Results posted
• Hydroxychloroquine Versus Pioglitazone in Combination Treatment for Type 2 Diabetes MellitusTerminatedNCT02303405Phase 2Results posted
• HCQ on PAR-4 Levels in Patients With Resectable Solid TumorsCompletedNCT02232243Phase 1Results posted
• Inducing Immune Quiescence to Prevent HIV Infection in WomenCompletedNCT02079077Not applicableResults posted
• Metabolic Effects of HydroxychloroquineTerminatedNCT02026232Not applicableResults posted
• Phase 1-2 Trial HCQ Plus TACE in Unresectable HCCTerminatedNCT02013778Phase 1/2Results posted
• Randomized Phase II Trial of Pre-Operative Gemcitabine and Nab Paclitacel With or With Out HydroxychloroquineCompletedNCT01978184Phase 2Results posted
• A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue SarcomaTerminatedNCT01842594Phase 2Results posted
• Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis CTerminatedNCT01833845Phase 1/2Results posted
• Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating Patients With Progressive Metastatic Castrate Refractory Prostate CancerTerminatedNCT01828476Phase 2Results posted

← Hydroxychloroquine overview