Drug
Etoposide clinical trials
Also written VP-16, VP-16-213, Vepesid and Toposar.
Includes 26 studies of Etoposide phosphate.
- studies test it
- 654
- open now
- 83
- in phase 3
- 121
- first study started
- 1990
Keep track of what changes. Save the Etoposide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
647 studies that test it; most in 2007 (28); 1 more planned to start later
| Year | Studies |
|---|---|
| 1990 | 3 |
| 1991 | 4 |
| 1992 | 2 |
| 1993 | 8 |
| 1994 | 10 |
| 1995 | 7 |
| 1996 | 13 |
| 1997 | 8 |
| 1998 | 23 |
| 1999 | 15 |
| 2000 | 26 |
| 2001 | 18 |
| 2002 | 17 |
| 2003 | 21 |
| 2004 | 22 |
| 2005 | 19 |
| 2006 | 20 |
| 2007 | 28 |
| 2008 | 22 |
| 2009 | 24 |
| 2010 | 28 |
| 2011 | 15 |
| 2012 | 18 |
| 2013 | 25 |
| 2014 | 19 |
| 2015 | 23 |
| 2016 | 23 |
| 2017 | 28 |
| 2018 | 20 |
| 2019 | 16 |
| 2020 | 18 |
| 2021 | 23 |
| 2022 | 21 |
| 2023 | 17 |
| 2024 | 15 |
| 2025 | 17 |
| 2026 | 11 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 7
- Phase 1
- 171
- Phase 2
- 390
- Phase 3
- 121
- Phase 4
- 12
- No phase
- 28
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 49 · Other 605
Children's Oncology Group (45) · National Cancer Institute (NCI) (38) · St. Jude Children's Research Hospital (24) · City of Hope Medical Center (21) · M.D. Anderson Cancer Center (20) · Memorial Sloan Kettering Cancer Center (17) · Alliance for Clinical Trials in Oncology (14) · University of Washington (12)
Often tested with
Tested in the same studies.
Cyclophosphamide (204) · Carboplatin (179) · Cisplatin (148) · Cytarabine (112) · Vincristine (111) · Doxorubicin (99) · Ifosfamide (99) · Melphalan (63)
Studies
Open first, then newest update. How each study uses Etoposide is read from its arms, and is right about nine times in ten.
Testing it · 654
- Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHLRecruitingPhase 2New York Medical CollegeNCT02393157Written as Etoposide
- A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruitingPhase 3National Cancer Institute (NCI)NCT05675410Written as Etoposide
- Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin LymphomaRecruitingPhase 2University of WashingtonNCT07097363Written as Etoposide
- A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon®-Rosetta35)RecruitingPhase 1/2Boehringer IngelheimNCT07843940Written as Etoposide
- Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic LeukemiaRecruitingPhase 2Mayo ClinicNCT03418038Written as Etoposide
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingPhase 1H. Lee Moffitt Cancer Center and Research InstituteNCT07194044Written as Etoposide
- Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed MedulloblastomaRecruitingPhase 2St. Jude Children's Research HospitalNCT05535166Written as Etoposide
- Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Carboplatin and Atezolizumab in Transformed Small Cell Lung Cancer Patients From Adenocarcinoma After EGFR TKI TreatmentRecruitingPhase 2Sehhoon ParkNCT06830694Written as Atezolizumab, Etoposide, Carboplatin, Tarlatamab
- Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic LeukaemiaRecruitingPhase 2/3St. Anna KinderkrebsforschungNCT01949129Written as VP16
- Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell TumoursRecruitingPhase 3University of SydneyNCT02582697Written as Etoposide
- N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With NeuroblastomaRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT06528496Written as Etoposide
- A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)RecruitingPhase 3Children's Oncology GroupNCT06401330Written as Etoposide
- Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell TumorsRecruitingPhase 3Children's Oncology GroupNCT03067181Written as Etoposide
- UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AMLRecruitingEarly Phase 1Baylor College of MedicineNCT07059975Written as Etoposide
- Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/LymphomaRecruitingEarly Phase 1New York Medical CollegeNCT03719105Written as Etoposide
- Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/LeukemiaRecruitingPhase 2M.D. Anderson Cancer CenterNCT03136146Written as Etoposide
- Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT CarcinomaRecruitingPhase 1/2National Cancer Institute (NCI)NCT05019716Written as Etoposide
- Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA StudyRecruitingPhase 2University of WashingtonNCT06039371Written as Etoposide
- Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of RecurrenceRecruitingPhase 3M.D. Anderson Cancer CenterNCT03583710Written as Etoposide
- Toripalimab Combined With Beat Chemotherapy in the Treatment of Advanced Back-line Small Cell Lung CancerNot yet recruitingPhase 2Henan Cancer HospitalNCT07698054Written as Toripalimab; Etoposide
See all 654 studies that test Etoposide →
Given in every arm · 455 — Etoposide is usual care beside what is tested
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitingPhase 2National Cancer Institute (NCI)NCT06406465Written as Etoposide
- Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the LungRecruitingPhase 2/3National Cancer Institute (NCI)NCT05058651Written as Etoposide
- Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk NeuroblastomaRecruitingPhase 3National Cancer Institute (NCI)NCT06172296Written as Etoposide
- DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard ChemoimmunotherapyRecruitingPhase 3Boehringer IngelheimNCT07472517Written as etoposide
- A Trial of LBL-024 Combined With Platinum-based Chemotherapy for the Treatment of Advanced EP-NECNot yet recruitingPhase 3Nanjing Leads Biolabs Co.,LtdNCT07720193Written as Etoposide injection
- Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK StudyNot yet recruitingPhase 2AIDS Malignancy ConsortiumNCT07662928Written as Etoposide
- Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)RecruitingPhase 1National Cancer Institute (NCI)NCT04301076Written as Etoposide
- Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung CancerRecruitingPhase 3BioNTech SENCT06712355Written as Etoposide
- A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).RecruitingPhase 3Bristol-Myers SquibbNCT06646276Written as Etoposide
- Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS TumorsRecruitingPhase 2Medical University of ViennaNCT01356290Written as Etoposide
- DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard ChemotherapyRecruitingPhase 3Boehringer IngelheimNCT07544654Written as Etoposide
- A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerRecruitingPhase 2AbbVieNCT07155174Written as Etoposide
- A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin LymphomaRecruitingPhase 1/2Hoffmann-La RocheNCT05533775Written as Etoposide
- Eflornithine (DFMO) for Ewing Sarcoma and OsteosarcomaRecruitingPhase 2Milton S. Hershey Medical CenterNCT07321912Written as Etoposide
- Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell LymphomaRecruitingPhase 2Alliance for Clinical Trials in OncologyNCT04803201Written as Etoposide
- Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose Chemotherapy In Refractory And Relapsed Germ Cell TumorsNot yet recruitingPhase 1/2M.D. Anderson Cancer CenterNCT07850973Written as Etoposide
- MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin LymphomaRecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT06377540Written as Etoposide
- Paclitaxel-Bleomycin/Etoposide/Cisplatin vs Bleomycin/Etoposide/Cisplatin in Poor-prognosis Non-seminomatous Germ Cell Tumors (NSGCT) and Unfavorable Tumor Marker Decline: Randomized Phase II TrialRecruitingPhase 2Blokhin's Russian Cancer Research CenterNCT07847190Written as Etoposide
- A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTRecruitingPhase 2Children's Oncology GroupNCT04684368Written as Etoposide
- ZG005 Plus Etoposide and Cisplatin vs. Etoposide and Cisplatin as First-Line Treatment for Advanced Neuroendocrine CarcinomaNot yet recruitingPhase 3Suzhou Zelgen Biopharmaceuticals Co.,LtdNCT07833839Written as Etoposide Injection
Showing 20 of 455.
As the comparator · 43 — what is tested is compared with Etoposide
- A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT07227597Written as Etoposide
- BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)RecruitingPhase 3SystImmune Inc.NCT07625644Written as Carboplatin+ Etoposide + Atezolizumab followed by Atezolizumab and Lurbinectedin
- A Study Comparing QLC5508 in Combination With QL2107 Versus Tislelizumab Plus Platinum-based Chemotherapy in Participants Wih Treatment-naïve Extensive-Stage Small Cell Lung CancerNot yet recruitingPhase 3Qilu Pharmaceutical Co., Ltd.NCT07802821Written as Etoposide
- A Study of YL201 in Combination With Serplulimab in Participants With Treatment-naïve Extensive-stage Small Cell Lung CancerRecruitingPhase 3MediLink Therapeutics (Suzhou) Co., Ltd.NCT07739758Written as Etoposide
- Study Comparing BEBT-908 Combined With R to SOC for the Treatment of Relapsed/Refractory Diffuse Large B-Cell LymphomaRecruitingPhase 3BeBetter Med IncNCT06792253Written as Etoposide Injection
- A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07)RecruitingPhase 3Sichuan Baili Pharmaceutical Co., Ltd.NCT07502300Written as Etoposide
- Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled StudyRecruitingPhase 2Sun Yat-sen UniversityNCT07583511Written as Etoposide
- Tamoxifen Versus Etoposide After First Recurrence in GBM PatientsRecruitingPhase 2AHS Cancer Control AlbertaNCT04765098Written as Etoposide
- Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors.Not yet recruitingPhase 1/2Shanghai Runshi Pharmaceutical Technology Co., LtdNCT06682611Written as Etoposide
- A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLHRecruitingNot applicableshifeng LouNCT05936086Written as Etoposide
- TC or BEP in Treating Patients With Ovarian Malignant Sex Cord-Stromal TumorsRecruitingPhase 3Beihua KongNCT02429700Written as Etoposide
- TC or BEP in Treating Patients With Malignant Ovarian Germ Cell TumorsRecruitingPhase 3Beihua KongNCT02429687Written as Etoposide
- ChiCGB vs BEAM in High-risk or R/R LymphomasRecruitingPhase 3Sichuan UniversityNCT05466318Written as Etoposide
- Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic TumorRecruitingPhase 3Weiguo LvNCT02639650Written as Etoposide
- Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine CarcinomasActive, not recruitingPhase 2ECOG-ACRIN Cancer Research GroupNCT02595424Written as Etoposide
- A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological FeaturesActive, not recruitingPhase 3AstraZenecaNCT06564844Written as Etoposide
- A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) MutationCompletedPhase 3Astellas Pharma IncNCT03182244Written as Etoposide
- Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell TumorsActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT01873326Written as Etoposide
- Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and AdolescentsActive, not recruitingPhase 3Dana-Farber Cancer InstituteNCT03020030Written as ETOPOSIDE
- A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin LymphomaActive, not recruitingPhase 3Regeneron PharmaceuticalsNCT06230224Written as Etoposide
Showing 20 of 43.
Codes
What other systems call Etoposide · ClinicalTrials.gg INT007464
- MeSH (NLM) D005047EtoposideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6PLQ3CP4P3ETOPOSIDEConfirmed FDA, NLM, Wikidata
- RxNorm 4179Confirmed FDA, Wikidata
- Wikidata Q418817etoposideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C491EtoposideOne source FDA
- DrugBank DB00773One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D005047 | Etoposide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6PLQ3CP4P3 | ETOPOSIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4179 | — | Confirmed FDA, Wikidata |
| Wikidata | Q418817 | etoposide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C491 | Etoposide | One source FDA |
| DrugBank | DB00773 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.