Children's Oncology Group clinical trials
Listed in the registry as: Research network.
The registry lists 447 studies whose lead sponsor is Children's Oncology Group. 35 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 20, 2026.
Keep track of what changes. Save the Children's Oncology Group studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesFocus areas
Conditions Children's Oncology Group leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Leukemia140Precursor Cell Lymphoblastic Leukemia-Lymphoma79Neuroblastoma59Neoplasms57Lymphoma46Central Nervous System Neoplasms42Sarcoma38Leukemia, Myeloid, Acute36Rhabdomyosarcoma31Wilms Tumor26Osteosarcoma24Kidney Neoplasms22Sarcoma, Ewing20Rhabdomyosarcoma, Embryonal17Lymphoma, Non-Hodgkin14Medulloblastoma14Myelodysplastic Syndromes14Neoplasms, Germ Cell and Embryonal14Glioma12Hodgkin Disease10Neuroectodermal Tumors, Primitive, Peripheral10
Studies
Recruiting first, then most recently updated. Showing 50 of 447. Browse all 447 →
- Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group StudiesRecruitingNCT00736749
- A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric PatientsRecruitingNCT05711667Phase 3
- Somatic Mosaicism in Twins Discordant for Childhood CancerRecruitingNCT06054295
- Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of EpendymomaNot yet recruitingNCT07848568Phase 1/2
- A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic InformationRecruitingNCT07621614Phase 2
- A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTRecruitingNCT04684368Phase 2
- A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to TreatNot yet recruitingNCT07830667Phase 1/2
- A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 MutationsRecruitingNCT04293562Phase 3
- Testing the Addition of an Anti-Cancer Drug, Daraxonrasib, for Relapsed or Refractory Solid Tumors With RAS MutationsNot yet recruitingNCT07819838Phase 1/2
- CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and LymphomaRecruitingNCT04870944Phase 1/2
- Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid LeukemiaRecruitingNCT07022678Phase 3
- Quality of End-of-Life Care for Children With CancerRecruitingNCT07412002
- Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With CancerRecruitingNCT06513962Phase 3
- Project: Every Child for Younger Patients With CancerRecruitingNCT02402244
- A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin LymphomaRecruitingNCT05705531
- A Study to Give Treatment Inside the Eye to Treat RetinoblastomaRecruitingNCT05504291Phase 2
- Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With OsteosarcomaRecruitingNCT05235165Phase 3
- A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)RecruitingNCT06401330Phase 3
- Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)RecruitingNCT03126916Phase 3
- Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell TumorsRecruitingNCT03067181Phase 3
- A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing LossRecruitingNCT05382338Phase 3
- A Study of Lower Radiotherapy Dose to Treat Children With CNS GerminomaRecruitingNCT06368817Phase 2
- A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWTRecruitingNCT04322318Phase 2
- Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid TumorsRecruitingNCT04851119Phase 1/2
- A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to TherapyRecruitingNCT06247787Phase 1
- Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative RhabdomyosarcomaRecruitingNCT05304585Phase 3
- Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLyRecruitingNCT03959085Phase 3
- Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary BlastomaRecruitingNCT06647953Phase 3
- A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute LeukemiaRecruitingNCT05702645
- A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)RecruitingNCT07466316Phase 3
- Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)Not yet recruitingNCT07072585Phase 2/3
- Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentRecruitingNCT01790152
- Backtracking Leukemia-Typical Somatic Mutations in Cord BloodRecruitingNCT05014165
- A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos StudyRecruitingNCT06410209Phase 2
- Molecular Epidemiology of Pediatric Germ Cell TumorsRecruitingNCT05564026
- Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk NeuroblastomaActive, not recruitingNCT02176967Phase 3
- Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 MutationsActive, not recruitingNCT03581292Phase 2
- A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at HomeSuspendedNCT06639958Not applicable
- Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaActive, not recruitingNCT03007147Phase 3
- Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the BodyTerminatedNCT06820957Phase 2/3
- A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by SurgeryActive, not recruitingNCT04195399Phase 2
- Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid LeukemiaActive, not recruitingNCT04258943Phase 1/2
- Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaActive, not recruitingNCT02981628Phase 2
- Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk NeuroblastomaWithdrawnNCT06858501Phase 2
- Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After SurgeryActive, not recruitingNCT03533582Phase 3
- Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVETerminatedNCT05020951
- Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation TherapyCompletedNCT01503086Not applicable
- A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory LeukemiaActive, not recruitingNCT05761171Phase 2
- Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid LeukemiaActive, not recruitingNCT04158739Phase 1
- Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar CarcinomaSuspendedNCT06620302Phase 1/2