Gingival Recession clinical trials
The registry lists 426 studies for Gingival Recession across more than 10 countries. 106 are recruiting or about to start. 397 of them are mainly about Gingival Recession (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Cairo University (35) · University of Sao Paulo (19) · Universidade Estadual Paulista Júlio de Mesquita Filho (14) · Postgraduate Institute of Dental Sciences Rohtak (14) · Krishnadevaraya College of Dental Sciences & Hospital (9) · G. d'Annunzio University (9) · Gazi University (8) · Universitat Internacional de Catalunya (7)
What is being tested here
Drugs under test in Gingival Recession studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III Recessions · Phase 3 · Cairo University
- Jan 2027New In Situ Model Design for Caries and Erosion · Phase 3 · Indiana University
- Sep 2027Topical Phenytoin for Management of Gingival Recession · Phase 3 · Cairo University
- Sep 2027Surgical Treatment for Gingival Recessions After Orthodontic Treatment · Phase 3 · Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
- Dec 2026Clinical Evaluation of (TCAF) Versus (CAF) Combined With Connective Tissue Graft in the Treatment of Multiple RT2 Gingival Recession Sites · Cairo University
- Dec 2026Adding Effect of Cross-linked Hyaluronic Acid to Microneedling After Coronally Advanced Flap in Isolated RT1 Recession · Cairo University
- Dec 2026Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional Study · Postgraduate Institute of Dental Sciences Rohtak
- Dec 2026Free Mucogingival Graft for Isolated Root Coverage · Universidad de Murcia
- Dec 2026V-CAF Technique for Miller Class III Gingival Recession · University of Medicine and Pharmacy at Ho Chi Minh City
- Dec 2026Role of Manuka Honey in Lowering Pain and Boosting Healing After Gum Graft Surgery. · Nancy Mouradian
Who these studies take
Of the 64 Gingival Recession studies recruiting now, 30 (47%) set no upper age limit and 31 (48%) stop at 75 or younger. 1 (2%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 36 (56%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 59 (92%) | 59 (92%) |
| 30 | 64 (100%) | 64 (100%) |
| 40 | 64 (100%) | 64 (100%) |
| 50 | 62 (97%) | 62 (97%) |
| 65 | 46 (72%) | 46 (72%) |
| 75 | 33 (52%) | 33 (52%) |
| 85 | 33 (52%) | 33 (52%) |
Across all 426 studies, recruiting or not: 61% stop at 75 or younger and 51% at 65; 5% take children; <1% are for women only and 0% for men only; 65% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Gingival Recession studies take
Of 235 interventional studies with no phase under Gingival Recession, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 19 mo11–30 · 235 studies | — | 19 mo11–30 · 233 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting3
- Oral Mucosa Wound Healing After Gingival Recession Treatment in Diabetic Patients. A Clinical Study.Nov 10, 2026NCT07470281
- Volume-Stable Collagen Matrix Versus Subepithelial Connective Tissue Graft for Multiple Gingival RecessionsNov 10, 2026NCT07613775
- Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical TrialOct 22, 2026NCT07500935
Newly registered3
- Clinician- vs. Patient-Reported Esthetic Outcomes After Coronally Advanced FlapNov 9, 2026NCT07924787
- i-PRF-Based Bioactive Matrix vs. Connective Tissue Graft in the Treatment of Gingival RecessionsNov 5, 2026NCT07918326
- Comparison of Connective Tissue and PRF in Gingival RecessionOct 16, 2026NCT07877064
Studies
Recruiting first, then most recently updated. Showing 50 of 426. Browse all 426 → or search them.
- Oral Mucosa Wound Healing After Gingival Recession Treatment in Diabetic Patients. A Clinical Study.RecruitingNCT07470281Not applicable1 country
- Volume-Stable Collagen Matrix Versus Subepithelial Connective Tissue Graft for Multiple Gingival RecessionsRecruitingNCT07613775Not applicable1 country
- Clinician- vs. Patient-Reported Esthetic Outcomes After Coronally Advanced FlapNot yet recruitingNCT07924787Not applicable
- Free Soft Tissue Grafts (FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)Not yet recruitingNCT07713199Not applicable1 country
- i-PRF-Based Bioactive Matrix vs. Connective Tissue Graft in the Treatment of Gingival RecessionsRecruitingNCT07918326Not applicable1 country
- Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical TrialRecruitingNCT07500935Not applicable1 country
- Evaluation of the Effect of Smoking on Palatal Donor Site Tissue Profile in the Success of Connective Tissue GraftsNot yet recruitingNCT07777185Not applicable1 country
- Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival GraftRecruitingNCT07751211Not applicable1 country
- Impact of Root Surface Conditioning With Erythritol Air Polishing and Hand Instrumentation on Recession Coverage Using the Modified Tunnel Technique and Subepithelial Connective Tissue Graft.RecruitingNCT07403006Not applicable1 country
- Influence of Keratinized Tissue Width and Attached Gingiva Width on Root Coverage in Patients With Recession Defects: A Prospective Clinical StudyRecruitingNCT07576439Not applicable1 country
- Dimensional Changes: Randomized Clinical TrialNot yet recruitingNCT05684068Not applicable1 country
- Evaluation of the Effects of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Treatments, Administered in Addition to Free Gingival Graft Therapy, on Clinical Healing.Not yet recruitingNCT07804888Not applicable1 country
- The Effect of Vertically Coronally Advanced Flap With Sub-epithelial Connective Tissue Graft Versus Coronally Advanced Flap With Sub-epithelial Connective Tissue Graft on Gingival Recession.Not yet recruitingNCT07801677Not applicable1 country
- Hyaluronic Acid and Polynucleotides With Connective Tissue Graft and Coronally Advanced Flap for RT II Gingival RecessionNot yet recruitingNCT07771244Not applicable1 country
- AI-Based Prediction of Root Coverage Outcome From Intraoral PhotographsRecruitingNCT077753651 country
- Surgical Treatment for Gingival Recessions After Orthodontic TreatmentRecruitingNCT07763808Phase 2/31 country
- Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection TechniquesRecruitingNCT06892496Not applicable1 country
- Modified Coronally Advanced Tunnel for Mandibular Lingual Root CoverageEnrolling by invitationNCT07590960Not applicable1 country
- Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal MatrixRecruitingNCT04920136Not applicable1 country
- Clinical and Histological Evaluation of Subepithelial Connective Tissue Graft Maturation at Different Healing Timepoints, With and Without Topical Application of a Polynucleotide- and Hyaluronic Acid-Based GelNot yet recruitingNCT07708051Not applicable
- Root Coverage Performance of Restorative Materials in Class V CavitiesRecruitingNCT07687654Not applicable1 country
- Gingival Recession (RT1) Treatment With Different Gingival Augmentation SurgeriesRecruitingNCT05688293Not applicable1 country
- Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival PhenotypeRecruitingNCT06988839Not applicable1 country
- Early Effects of Orthognathic Surgery on Periodontal Phenotype: A 6-Month Prospective Clinical and Radiographic EvaluationRecruitingNCT073490561 country
- Palatal Wound Healing After Free Gingival Graft SurgeryRecruitingNCT07409571Not applicable1 country
- Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded GumsRecruitingNCT06037161Not applicable1 country
- Topical Phenytoin for Management of Gingival RecessionNot yet recruitingNCT07590375Phase 2/3
- Changes of Soft Tissue Grafting: A Randomized StudyRecruitingNCT05633511Not applicable1 country
- Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional StudyRecruitingNCT075572771 country
- Taking Measurements of a Gum Graft Site as it HealsRecruitingNCT073864571 country
- Study of Hyaluronic Acid Used With Gum Surgery to Treat Gum Recession in AdultsNot yet recruitingNCT07529340Not applicable1 country
- Adding Effect of Cross-linked Hyaluronic Acid to Microneedling After Coronally Advanced Flap in Isolated RT1 RecessionNot yet recruitingNCT07520539Phase 1/2
- Management of Postoperative Pain Following Free Gingival Graft Harvesting Using Ora-Aid Versus Acrylic Palatal StentRecruitingNCT07523802Not applicable1 country
- Comparative Evaluation of Novel 3D Tunneling Technique Versus Modified Coronally Advanced Tunnel (MCAT) With Connective Tissue Graft in the Management of Multiple RT2 Gingival RecessionRecruitingNCT07526259Not applicable1 country
- The Impact of a 3D Imaging Tool on Reducing Gum Recession During Orthodontic Treatment With AlignersRecruitingNCT07513792Not applicable1 country
- Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III RecessionsRecruitingNCT06643507Phase 2/31 country
- Selective Versus Contiguous Connective Tissue Grafts in the Modified Tunnel TechniqueRecruitingNCT07453147Not applicable2 countries
- Gingival Recessions in Orthodontically Treated and Untreated Adult PatientsRecruitingNCT074455551 country
- A Novel Volume Stable Matrix for Gingival Recession Coverage at TeethRecruitingNCT07437417Not applicable1 country
- Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival SurgeryRecruitingNCT07430670Not applicable1 country
- Free Mucogingival Graft for Isolated Root CoverageRecruitingNCT05851248Not applicable1 country
- Changes in Soft Tissue Thickness Following Multiple Coronally Advanced Tunnel (MCAT) vs Vestibular Incision Subperiosteal Tunnel Access (VISTA)RecruitingNCT07200258Not applicable1 country
- 3D Digital Assessment of Soft Tissue Changes After Modified FGGRecruitingNCT07409558Not applicable1 country
- Clinical Evaluation Comparing Tunneled Coronally Advanced Flap and Modified Coronally Advanced Tunnel With Connective Tissue Graft for Managing Single Gum RecessionNot yet recruitingNCT07239180Not applicable
- Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.RecruitingNCT06940050Not applicable1 country
- Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Maxilla.RecruitingNCT07158528Not applicable1 country
- Comparing TCAF and MTUN With Soft Tissue Grafting for Treating Single Recessions in the PremandibleRecruitingNCT07158541Not applicable1 country
- Effectiveness of Meshed Free Gingival Graft for Widening of Keratinized TissuesRecruitingNCT06037694Not applicable1 country
- Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival RecessionsNot yet recruitingNCT06986525Not applicable1 country
- L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant PlacementRecruitingNCT07102758Not applicable1 country