Drug
Carboxymethylcellulose clinical trials
- studies test it
- 15
- open now
- 2
- in phase 3
- 1
- first study started
- 2004
Keep track of what changes. Save the carboxymethylcellulose studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
14 studies that test it; most in 2009 (2)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2007 | 1 |
| 2009 | 2 |
| 2011 | 2 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 2
- 1
- Phase 3
- 1
- Phase 4
- 10
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 7
Allergan (5) · Innovative Medical (2) · Minia University (1) · University of Minnesota (1) · University of Florida (1) · Centre Hospitalier Intercommunal Creteil (1) · University of Campinas, Brazil (1) · Pokhara Academy of Health Sciences, Western Regional Hospital (1)
Often tested with
Tested in the same studies.
Glycerol (4) · Hyaluronic Acid (2) · Naltrexone (1) · Psyllium (1) · Gum Arabic (1) · Hypromellose Derivatives (1) · Propylene Glycol (1)
Studies
Open first, then newest update. How each study uses carboxymethylcellulose is read from its arms, and is right about nine times in ten.
Testing it · 15
- Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye DiseaseRecruitingPhase 4Andover Research Eye InstituteNCT07676084Written as Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5%
- Randomized Clinical Trial of Artificial Tears With and Without Preservatives in Patients With Dry Eye DiseaseNot yet recruitingPhase 4Pokhara Academy of Health Sciences, Western Regional HospitalNCT07635849Written as Carboxy methyl cellulose
- The Use of Naltrexone Hydrochloride to Promote Healing in Patients With Resistant Non-infectious Corneal UlcerCompletedNot applicableMinia UniversityNCT05924893Written as Carboxy methyl cellulose
- Dietary Fiber for Fecal IncontinenceCompletedNot applicableUniversity of MinnesotaNCT01738607Written as carboxymethylcellulose
- Effects of Carboxymethylcellulose Artificial Tears on the Eye MicrobiomeCompletedPhase 4University of FloridaNCT05292755Written as Carboxymethylcellulose (CMC) Artificial Tears
- A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry EyeCompletedPhase 4AllerganNCT02117687Written as carboxymethylcellulose 0.5%/glycerin 0.9%
- Healing of Persistent Epithelial DefectsWithdrawnNot applicableMilton S. Hershey Medical CenterNCT02395952Written as carboxymethylcellulose sodium
- Ocular Discomfort Assessment After Intravitreal InjectionsCompletedNot applicableCentre Hospitalier Intercommunal CreteilNCT02806830Written as Optive
- A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye SymptomsCompletedPhase 4AllerganNCT02028754Written as Sodium Carboxymethylcellulose
- The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic PatientsCompletedPhase 4University of Campinas, BrazilNCT01280110Written as Carboxymethylcellulose
- Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and SymptomsCompletedPhase 4AllerganNCT00938704Written as carboxymethylcellulose 0.5% +glycerin 0.9%
- Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry EyeCompletedPhase 4AllerganNCT00987727Written as carboxymethylcellulose 0.5% , glycerin 0.9% (OPTIVE® MD)
- A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye DropCompletedPhase 2/3AllerganNCT00243711Written as Carboxymethylcellulose sodium and Glycerin
- Refractive Surgery and Optive Compatibility StudyCompletedPhase 4Innovative MedicalNCT00469157Written as Optive
- A Comparison of Optive in Patients Previously Using Systane for the Treatment of Dry EyeCompletedPhase 4Innovative MedicalNCT00399230Written as Optive
Given in every arm · 1 — carboxymethylcellulose is usual care beside what is tested
As the comparator · 7 — what is tested is compared with carboxymethylcellulose
- Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®Not yet recruitingPhase 1Laboratorios Sophia S.A de C.V.NCT06375343Written as Optive®
- A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry EyeCompletedPhase 3The University of New South WalesNCT02871440Written as Optive
- A Study to Compare the Safety and Efficacy of a New Eye Drop Formulation With REFRESH PLUS® in Participants Following LASIK Refractive SurgeryCompletedPhase 3AllerganNCT01886690Written as carboxymethylcellulose sodium based eye drops
- A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.CompletedPhase 3AllerganNCT02553772Written as Carboxymethylcellulose Sodium 0.5%
- Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK SurgeryCompletedNot applicableAllerganNCT00544713Written as Carboxymethylcellulose
- Acupuncture for Dry EyeCompletedPhase 3Korea Institute of Oriental MedicineNCT01105221Written as Refresh Plus
- Safety and Efficacy of an Artificial Tear for the Treatment of Dry EyeCompletedNot applicableAllerganNCT00514852Written as Carboxymethylcellulose
Codes
What other systems call carboxymethylcellulose · ClinicalTrials.gg INT007150
- MeSH (NLM) D002266Carboxymethylcellulose SodiumConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 05JZI7B19XCARBOXYMETHYLCELLULOSEConfirmed FDA, NLM
- RxNorm 2062One source FDA
- NCI Thesaurus C83594CarboxymethylcelluloseOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002266 | Carboxymethylcellulose Sodium | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 05JZI7B19X | CARBOXYMETHYLCELLULOSE | Confirmed FDA, NLM |
| RxNorm | 2062 | — | One source FDA |
| NCI Thesaurus | C83594 | Carboxymethylcellulose | One source FDA |
Also registered as carboxymethylcellulose sodium, unspecified (UNII K679OBS311 · RxNorm 491498).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.