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Dry Eye Syndromes clinical trials

The registry lists 1,367 studies for Dry Eye Syndromes across more than 10 countries. 208 are recruiting or about to start. 1,156 of them are mainly about Dry Eye Syndromes (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 3 narrower conditions too, such as Sjogren's Syndrome: 1,667 studies, 295 open.

ClinicalTrials.gov finds 1,718 studies for Dry Eye Syndromes. How that becomes 1,364 here

This page counts the studies the registry files under Dry Eye Syndromes, and those it files under no condition that list Dry Eye Syndromesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,718Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −294Filed under a narrower condition, counted on its own pageSjogren's Syndrome 267 · Keratoconjunctivitis Sicca 17 · Xerophthalmia 8
  3. −2List Dry Eye Syndromes as a condition, but the registry did not file them under itMost often written as “Moderate to Severe Dry Eye Syndrome” (1) and “Inflammatory Dry Eye Disease” (1). The registry filed them under other conditions only, most often Lymphoma, Follicular (1) and Hematologic Neoplasms (1).
  4. −58Match it another way15 name it in the title and 43 by a synonym or other text the search reads.
  5. 1,364The count on this page9 of them list Dry Eye Syndromes in their own words; the registry filed them under no condition.

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Status

Completed
910
Status unknown
131
Recruiting
116
Not yet recruiting
83
Terminated
51
Withdrawn
32

Phase

Phase 2
228
Phase 4
220
Phase 3
179
Phase 1
76
Early Phase 1
15

Where

United States
543
China
105
Korea, Republic of
49
France
47
Canada
45
Italy
44

Who runs them

Alcon Research (85) · Allergan (42) · Medical University of Vienna (24) · Bausch & Lomb Incorporated (23) · Singapore National Eye Centre (20) · He Eye Hospital (17) · Innovative Medical (15) · University of Alabama at Birmingham (15)

What is being tested here

Drugs under test in Dry Eye Syndromes studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Acoltremon9617
Cyclosporine5745
Hyaluronic Acid3218
Propylene Glycol3012
Lifitegrast2522
Varenicline2413
Diquafosol tetrasodium2313
Carboxymethylcellulose2112
Lubricant Eye Drops2010
Diquafosol217

Drug classes tested here Calcineurin inhibitors 5 open · Corticosteroids 1 open · Antihistamines 8 · Tyrosine kinase inhibitors (TKIs) 4

Coming up

12phase 3 studies under way
81studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 116 Dry Eye Syndromes studies recruiting now, 73 (63%) set no upper age limit and 24 (21%) stop at 75 or younger. 7 (6%) take children under 18. 3 (3%) are for women only and 0 (0%) for men only; 29 (25%) take healthy volunteers.

Recruiting studies that take each age, of 116
AgeWomenMen
106 (5%)6 (5%)
1887 (75%)87 (75%)
30109 (94%)106 (91%)
40108 (93%)106 (91%)
50109 (94%)108 (93%)
65105 (91%)104 (90%)
7599 (85%)99 (85%)
8584 (72%)84 (72%)

Across all 1,367 studies, recruiting or not: 19% stop at 75 or younger and 12% at 65; 5% take children; 2% are for women only and <1% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Dry Eye Syndromes studies take

Of 112 phase 4 interventional studies under Dry Eye Syndromes, half reached primary completion within 12 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 16 mo4–13 · 34 studies——
Phase 1/214 mo7–24 · 21 studies——
Phase 27 mo5–12 · 91 studies7 mo4–11 · 75 studies—
Phase 2/311 mo6–18 · 15 studies——
Phase 310 mo7–15 · 96 studies9 mo6–15 · 81 studies—
Phase 412 mo5–23 · 112 studies8 mo4–15 · 28 studies13 mo7–28 · 84 studies
Interventional, no phase10 mo4–18 · 312 studies9 mo4–13 · 113 studies12 mo5–25 · 199 studies
Observational12 mo5–64 · 69 studies—21 mo9–64 · 53 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting2

Results posted3

Newly registered14

Show 9 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,367. Browse all 1,367 → or search them.