Febuxostat clinical trials
Also written Uloric, TMX-67, Adenuric and Tei-6720.
How each study uses Febuxostat is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- 13 Feb 2009 · ULORIC · NDA 021856 (FDA, Drugs@FDA)
- European Union
- 21 Apr 2008 · Adenuric · EMEA/H/C/000777 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
69 studies that test it; most in 2010 (6)
| Year | Studies |
|---|---|
| 2001 | 2 |
| 2002 | 1 |
| 2003 | 2 |
| 2006 | 1 |
| 2007 | 1 |
| 2009 | 1 |
| 2010 | 6 |
| 2011 | 6 |
| 2012 | 6 |
| 2013 | 5 |
| 2014 | 5 |
| 2015 | 5 |
| 2016 | 2 |
| 2017 | 5 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 4 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 2 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 35 · Other 34
Takeda (18) · Ain Shams University (4) · Tanta University (3) · Gilead Sciences (2) · Jiangsu HengRui Medicine Co., Ltd. (2) · Shanghai 10th People's Hospital (2) · Ardea Biosciences, Inc. (2) · Menarini Group (2)
Often tested with
Tested in the same studies.
Allopurinol (3) · Arhalofenate (2) · Colchicine (2) · Ruzinurad (2) · Benzbromarone (2) · Vitamin E (1) · Epaminurad (1) · Methotrexate (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Tested against it · 2 phase 3 studies under way
Febuxostat is the comparator. A study of two new drugs counts under both.
- 1Tigulixostat · Innovent Biologics Technology Limited (Shanghai R&D Center) · next primary completion Apr 2027
- 1AR882 · Guangzhou Ruianbo Pharmaceutical Technology Co., Ltd
Reaching primary completion within a year · 4
Studies that test Febuxostat.
- Nov 2026Comparison of the Effect of Allopurinol Versus Febuxostat on Serum Uric Acid in Patients With Chronic Kidney Disease Associated With HyperuricemiaNot applicable · Nishtar Medical University
- Jun 2027Boosting Osimertinib Blood Brain Barrier PenetrationPhase 2 · Maastricht University Medical Center
- Jun 2027HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-EffectivenessPhase 4 · Haiphong University of Medicine and Pharmacy
- Jul 2027The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and HyperuricemiaPhase 2 · Jiangsu HengRui Medicine Co., Ltd.
Studies
Open first, then newest update. How each study uses Febuxostat is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 69
- Clinical Study to Evaluate the Efficacy of Febuxostat in the Treatment of Conservatively Managed Intracranial Hemorrhage PatientsRecruitingPhase 2Tanta UniversityNCT07701512Written as Febuxostat 40 mg
- Boosting Osimertinib Blood Brain Barrier PenetrationRecruitingPhase 2Maastricht University Medical CenterNCT07485452Written as Osimertinib & febuxostat
- The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and HyperuricemiaRecruitingPhase 2Jiangsu HengRui Medicine Co., Ltd.NCT07362355Written as SHR4640 ; Febuxostat
- HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-EffectivenessNot yet recruitingPhase 4Haiphong University of Medicine and PharmacyNCT07369622Written as Febuxostat
- Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy SubjectsNot yet recruitingPhase 1JemincareNCT07181265Written as Febuxostat Tablets
- A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's DiseaseRecruitingPhase 1Fujita Health UniversityNCT07170475Written as Febuxostat
- Clinical Study to Evaluate the Possible Efficacy and Safety of Febuxostat in Patients With Ulcerative Colitis Treated With MesalamineNot yet recruitingEarly Phase 1Tanta UniversityNCT06525974Written as Febuxostat
- Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed AdministrationCompletedPhase 3University Hospital, RouenNCT05109936Written as Adenuric
- Comparison of the Effect of Allopurinol Versus Febuxostat on Serum Uric Acid in Patients With Chronic Kidney Disease Associated With HyperuricemiaActive, not recruitingNot applicableNishtar Medical UniversityNCT07850713Written as Febuxostat
- Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With GoutCompletedPhase 2Gilead SciencesNCT02252835Written as Febuxostat
- Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media ThicknessCompletedPhase 1Ain Shams UniversityNCT06997952Written as Febuxostat 40 mg
- A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout PatientsCompletedPhase 3JW PharmaceuticalNCT05815901Written as Febuxostat 40 mg
- Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients with HyperuricemiaActive, not recruitingPhase 2Tanta UniversityNCT05574036Written as Febuxostat 80 MG Oral Tablet
- Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine ExcretionCompletedPhase 4Landspitali University HospitalNCT02752633Written as Febuxostat
- Febuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD PatientsCompletedPhase 4Ain Shams UniversityNCT05474560Written as Febuxostat 40 mg plus lifestyle intervention
- Effects of Hyperuricemia Reversal on Features of the Metabolic SyndromeCompletedPhase 4University of Texas Southwestern Medical CenterNCT01654276Written as Febuxostat
- A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy SubjectsCompletedPhase 1Seoul National University HospitalNCT05575297Written as Febuxostat Tablets
- The Impact of Urate-lowering Therapy on Kidney Function (IMPULsKF)Status unknownPhase 4Medical Practice Prof D. IvanovNCT03336203Written as Febuxostat 80 MG Oral Tablet or Allopurinol 300 MG Oral Tablet
- Renoprotective Effect of Febuxostat on Contrast Induced Acute Kidney Injury in Chronic Kidney Disease Patients Stage 3CompletedNot applicableAin Shams UniversityNCT05264584Written as Febuxostat 80 MG
- Febuxostat for Tumor Lysis Syndrome Prevention in Hematological Malignancies of Paediatric Patients and AdultsTerminatedPhase 1/2Menarini GroupNCT03605212Written as Febuxostat
See all 69 studies that test Febuxostat →
Given beside what is tested · 12 — Febuxostat is usual care or a partner of the new treatment
- Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCTNot yet recruitingNot applicableXueMei GuoNCT07326839Written as Febuxostat 40mg Tab
- Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic PatientsCompletedPhase 2Mostafa BahaaNCT06995339Written as Febuxostat Tablets
- Clinical Study of SHR4640 Tablets Combined With Febuxostat Tablets in the Treatment of Primary Gout and HyperuricemiaStatus unknownPhase 2Jiangsu HengRui Medicine Co., Ltd.NCT05513976Written as febuxostat tablet
- A Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With GoutCompletedPhase 2TWi Biotechnology, Inc.NCT02287818Written as Febuxostat
- The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult MalesCompletedPhase 1Arthrosi TherapeuticsNCT04347005Written as Cohort 9: AR882 in combination with febuxostat
- Efficacy and Safety of Simiaowan in Prevention of Acute Flares in Chronic Gout Patients Initiating Febuxostat TherapyStatus unknownNot applicableGuang'anmen Hospital of China Academy of Chinese Medical SciencesNCT04069325Written as febuxostat
- A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UACompletedPhase 2AstraZenecaNCT03316131Written as Febuxostat
- A Proof-of-Concept Study of AC-201 to Prevent Gout FlaresCompletedPhase 2TWi Biotechnology, Inc.NCT01712204Written as Febuxostat
- Lesinurad and Febuxostat Combination Extension Study in GoutCompletedPhase 3Ardea Biosciences, Inc.NCT01808144Written as febuxostat
- Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and FebuxostatCompletedPhase 3Ardea Biosciences, Inc.NCT01510769Written as Febuxostat
- A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia PatientsCompletedPhase 1/2AstraZenecaNCT02317861Written as Febuxostat
- Immune Molecular and Inflammatory Cytokines Dysfunction Analysis in Gout Patients With Different Urate LevelsCompletedPhase 4Tongji HospitalNCT02060552Written as Febuxostat
As the comparator · 8 — what is tested is compared with Febuxostat
- Clinical Trial of BR2251 Tablets for Patients With Primary Gout and HyperuricemiaNot yet recruitingPhase 2BioRay Pharmaceutical Co., Ltd.NCT07498647Written as Febuxostat
- Effect of Dotinurad in Hyperuricemia With HypertensionRecruitingPhase 4Saga UniversityNCT06834230Written as Febuxostat
- Study on the Efficacy and Safety of Thermotherapy in the Treatment of Refractory GoutNot yet recruitingNot applicableThe First Hospital of Jilin UniversityNCT06653686Written as Febuxostat
- Tigulixostat (IBI128) vs Febuxostat in GoutActive, not recruitingPhase 3Innovent Biologics Technology Limited (Shanghai R&D Center)NCT07414394Written as Febuxostat
- A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With GoutCompletedPhase 3Eisai Co., Ltd.NCT05007392Written as Febuxostat
- A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout SubjectsCompletedPhase 2Innovent Biologics (Suzhou) Co. Ltd.NCT06501534Written as Febuxostat
- Phase II/III Study of AR882 Capsules Compared to Febuxostat Tablets in Patients with Primary Gout and HyperuricemiaActive, not recruitingPhase 2/3Guangzhou Ruianbo Pharmaceutical Technology Co., LtdNCT06603142Written as Febuxostat 20MG Tablets
- Febuxostat-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without GoutCompletedPhase 3Mochida Pharmaceutical Company, Ltd.NCT03372200Written as Febuxostat
Codes
What other systems call Febuxostat · ClinicalTrials.gg INT006593
- MeSH (NLM) D000069465FebuxostatConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 101V0R1N2EFEBUXOSTATConfirmed FDA, NLM, Wikidata
- RxNorm 73689Confirmed FDA, Wikidata
- Wikidata Q417296febuxostatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C65629FebuxostatOne source FDA
- DrugBank DB04854One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069465 | Febuxostat | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 101V0R1N2E | FEBUXOSTAT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 73689 | — | Confirmed FDA, Wikidata |
| Wikidata | Q417296 | febuxostat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C65629 | Febuxostat | One source FDA |
| DrugBank | DB04854 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.