Drug
Allopurinol clinical trials
Also written Zyloprim.
Includes 1 study of Allopurinol sodium.
Keep track of what changes. Save the Allopurinol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
114 studies that test it; most in 2008 (8)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1998 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 3 |
| 2005 | 3 |
| 2006 | 2 |
| 2007 | 4 |
| 2008 | 8 |
| 2009 | 5 |
| 2010 | 7 |
| 2011 | 7 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 8 |
| 2015 | 6 |
| 2016 | 5 |
| 2017 | 6 |
| 2018 | 8 |
| 2019 | 5 |
| 2020 | 6 |
| 2021 | 3 |
| 2022 | 5 |
| 2023 | 7 |
| 2024 | 1 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Gout
- 12
Who runs them
Industry 22 · Other 96
Ardea Biosciences, Inc. (8) · AstraZeneca (6) · Tanta University (5) · University of Dundee (5) · The University of Texas at Arlington (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · Instituto Nacional de Cardiologia Ignacio Chavez (3) · Masonic Cancer Center, University of Minnesota (2)
Often tested with
Tested in the same studies.
Verinurad (7) · Rasburicase (4) · Lesinurad (4) · Febuxostat (3) · Fludarabine (3) · Cyclophosphamide (3) · Mycophenolic Acid (3) · Acetovanillone (3)
Studies
Open first, then newest update. How each study uses Allopurinol is read from its arms, and is right about nine times in ten.
Testing it · 118
- Role of Allopurinol in Prevention of Complications Related to Decompensated Cirrhosis of LiverRecruitingPhase 4Bangladesh Medical UniversityNCT07800598Written as Allopurinol Tablet
- Allopurinol in DepressionRecruitingPhase 2/3Tanta UniversityNCT07574060Written as Allopurinol 300 MG
- Allo HSCT Using RIC and PTCy for Hematological DiseasesRecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT05805605Written as Allopurinol 300 MG
- Uric Acid, Klotho and Salt Sensitivity in Young Adults Born PretermRecruitingEarly Phase 1Wake Forest University Health SciencesNCT04026776Written as Allopurinol
- HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-EffectivenessNot yet recruitingPhase 4Haiphong University of Medicine and PharmacyNCT07369622Written as Allopurinol Tablet
- The Effect of Allopurinol on the Risk of Cardiovascular Events in Patients with Cardiovascular RiskRecruitingPhase 3Poznan University of Medical SciencesNCT05943821Written as Allopurinol 200 mg
- Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary BypassRecruitingPhase 3dr. M.J.N.L. BendersNCT04217421Written as Allopurinol
- Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive OutcomeRecruitingPhase 3University Hospital TuebingenNCT03162653Written as Allopurinol
- Allopurinol and Trimetazidine as a Preventive of Acute Kidney Injury in PCI PatientsRecruitingPhase 4Beni-Suef UniversityNCT05540184Written as Allopurinol 300 MG
- Allopurinol and Pathogenesis of CirrhosisCompletedPhase 1/2Tanta UniversityNCT07033533Written as Allopurinol Tablet
- Allopurinol Improves Heart Function in African Americans With Resistant HypertensionCompletedPhase 2VA Office of Research and DevelopmentNCT05888233Written as Allopurinol
- Allopurinol Versus Atorvastatin to Prevent Complications of Liver CirrhosisCompletedPhase 2/3Tanta UniversityNCT05511766Written as Allopurinol 300 MG
- Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With GoutCompletedPhase 2InventisBio Co., LtdNCT05665699Written as Allopurinol
- Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With HyperuricemiaCompletedPhase 1/2Urica Therapeutics Inc.NCT06056570Written as dotinurad + allopurinol
- Evaluation of a Treatment With Allopurinol in Adenylosuccinate Lyase DeficiencyCompletedPhase 2Assistance Publique - Hôpitaux de ParisNCT03776656Written as Allopurinol
- ALLOPURINOL AND LISINOPRIL FOR DIABETIC KIDNEY PROTECTION: A COMPARATIVE STUDY IN NORMOURICEMIC TYPE 2 DIABETICSCompletedNot applicableNarowal Medical CollegeNCT07177898Written as Allopurinol
- Effect of Allopurinol on Markers of Mineral and Bone MetabolismCompletedNot applicableUniversity of Sao Paulo General HospitalNCT05601271Written as Allopurinol
- Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous GoutCompletedPhase 2Arthrosi TherapeuticsNCT05253833Written as Allopurinol Tablet
- Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)TerminatedPhase 1Washington University School of MedicineNCT05049863Written as Allopurinol
- Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine ExcretionCompletedPhase 4Landspitali University HospitalNCT02752633Written as Allopurinol
See all 118 studies that test Allopurinol →
Given in every arm · 18 — Allopurinol is usual care beside what is tested
- Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic LeukemiaRecruitingPhase 3Alliance for Clinical Trials in OncologyNCT03150693Written as Allopurinol
- Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)RecruitingPhase 2M.D. Anderson Cancer CenterNCT05536349Written as Allopurinol
- Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in GoutRecruitingPhase 4Massachusetts General HospitalNCT04875702Written as Allopurinol
- Trial of Magrolimab (Hu5F9-G4) in Combination With Rituximab or Rituximab + Chemotherapy in Participants With Relapsed/Refractory B-cell Non-Hodgkin's LymphomaTerminatedPhase 1/2Gilead SciencesNCT02953509Written as Allopurinol
- Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's LeukemiaCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00039130Written as Allopurinol
- A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell ReinfusionStatus unknownPhase 2Swedish Medical CenterNCT03570983Written as Allopurinol
- Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 1/2National Cancer Institute (NCI)NCT00061945Written as allopurinol
- A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal ImpairmentTerminatedPhase 4Ironwood Pharmaceuticals, Inc.NCT03226899Written as XOI
- Busulfan and Cyclophosphamide Followed By ALLO BMTTerminatedNot applicableMasonic Cancer Center, University of MinnesotaNCT01685411Written as Allopurinol
- T-Cell Depleted Double UCB for Refractory AMLTerminatedPhase 2Masonic Cancer Center, University of MinnesotaNCT01464359Written as Allopurinol
- Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian Tube, and Primary Peritoneal CancerTerminatedPhase 2Masonic Cancer Center, University of MinnesotaNCT00652899Written as Allopurinol
- T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic CancerCompletedPhase 1Masonic Cancer Center, University of MinnesotaNCT00602693Written as Allopurinol
- Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout FlaresTerminatedPhase 3Regeneron PharmaceuticalsNCT01459796Written as Allopurinol
- Combining Lesinurad With Allopurinol in Inadequate RespondersCompletedPhase 3Ardea Biosciences, Inc.NCT01510158Written as Allopurinol
- Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00003700Written as Allopurinol
- Combining Lesinurad With Allopurinol in Inadequate RespondersCompletedPhase 3Ardea Biosciences, Inc.NCT01493531Written as Allopurinol
- Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout PatientsCompletedPhase 2Gilead SciencesNCT01399008Written as Allopurinol
- Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of AllopurinolCompletedPhase 4Regeneron PharmaceuticalsNCT01451645Written as allopurinol
As the comparator · 27 — what is tested is compared with Allopurinol
- A Study of Dotinurad Versus Allopurinol in Tophaceous GoutRecruitingPhase 3Crystalys TherapeuticsNCT07089888Written as Allopurinol
- A Study of Dotinurad Versus Allopurinol in Participants With GoutRecruitingPhase 3Crystalys TherapeuticsNCT07089875Written as Allopurinol
- Comparison of the Effect of Allopurinol Versus Febuxostat on Serum Uric Acid in Patients With Chronic Kidney Disease Associated With HyperuricemiaActive, not recruitingNot applicableNishtar Medical UniversityNCT07850713Written as allopurinol
- Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With GoutCompletedPhase 2/3Atom Therapeutics Co., LtdNCT05818085Written as Allopurinol
- Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout PatientsCompletedPhase 3LG ChemNCT05586971Written as Allopurinol
- Extension Study of ABP-671 in Participants With GoutTerminatedPhase 2/3Atom Therapeutics Co., LtdNCT06276556Written as Allopurinol
- A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With GoutCompletedPhase 3Jiangsu HengRui Medicine Co., Ltd.NCT04956432Written as Allopurinol
- A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With GoutCompletedPhase 3Jiangsu HengRui Medicine Co., Ltd.NCT04052932Written as Allopurinol 300 MG
- Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic HyperuricemiaCompletedPhase 2AstraZenecaNCT02078219Written as Allopurinol
- Zurig (Febuxostat) 40mg Efficacy and Safety TrialCompletedPhase 4Getz PharmaNCT02600780Written as Allopurinol
- Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With GoutCompletedPhase 4Menarini International Operations Luxembourg SANCT02500641Written as Allopurinol 100 up to 600mg/day
- Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery DiseaseStatus unknownPhase 4Tel-Aviv Sourasky Medical CenterNCT03700645Written as Allopurinol
- Prednisone for Heart Failure Patients With HyperuricemiaCompletedPhase 2/3Hebei Medical UniversityNCT02129764Written as Allopurinol
- Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)CompletedPhase 3TakedaNCT01101035Written as Allopurinol
- Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout PatientsCompletedPhase 2Gilead SciencesNCT02063997Written as Allopurinol 300 mg
- Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell TransplantCompletedPhase 1Massachusetts General HospitalNCT00513474Written as allopurinol
- Safety and Efficacy of Oral Febuxostat in Subjects With GoutCompletedPhase 3Xijing HospitalNCT02082769Written as Allopurinol
- Febuxostat for Tumor Lysis Syndrome Prevention in Hematologic MalignanciesCompletedPhase 3Menarini GroupNCT01724528Written as Allopurinol
- A Study to Evaluate Safety and Efficacy of Oral Febuxostat in Patients With GoutCompletedPhase 3Astellas Pharma Taiwan, Inc.NCT01736514Written as Allopurinol
- Rasburicase (Fasturtec) Registration TrialTerminatedPhase 3SanofiNCT00607152Written as Allopurinol
Showing 20 of 27.
Codes
What other systems call Allopurinol · ClinicalTrials.gg INT006928
- MeSH (NLM) D000493AllopurinolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 63CZ7GJN5IALLOPURINOLConfirmed FDA, NLM, Wikidata
- RxNorm 519Confirmed FDA, Wikidata
- Wikidata Q412486allopurinolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C224AllopurinolOne source FDA
- DrugBank DB00437One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000493 | Allopurinol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 63CZ7GJN5I | ALLOPURINOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 519 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412486 | allopurinol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C224 | Allopurinol | One source FDA |
| DrugBank | DB00437 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.