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Polycystic Kidney, Autosomal Dominant clinical trials

The registry lists 185 studies for Polycystic Kidney, Autosomal Dominant across more than 10 countries. 42 are recruiting or about to start. 172 of them are mainly about Polycystic Kidney, Autosomal Dominant (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
94
Recruiting
30
Active, not recruiting
18
Status unknown
16
Terminated
13
Not yet recruiting
9

Phase

Phase 2
44
Phase 3
39
Phase 1
23
Phase 4
8
Early Phase 1
1

Where

United States
85
Italy
29
Germany
24
Netherlands
23
United Kingdom
20
France
20

Who runs them

Mayo Clinic (15) · University of Colorado, Denver (12) · Otsuka Pharmaceutical Development & Commercialization, Inc. (10) · Mario Negri Institute for Pharmacological Research (10) · Jemincare (7) · Vertex Pharmaceuticals Incorporated (7) · Kyorin University (4) · Palladio Biosciences (4)

What is being tested here

Drugs under test in Polycystic Kidney, Autosomal Dominant studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
JMKX003142606
VX-407105
Metformin124
Atorvastatin101
Sodium Bicarbonate101
Amiodarone101
Febuxostat101
Beta-hydroxybutyrate-1,3-butanediol monoester101
Bempedoic acid101
Hydrochlorothiazide111

Drug classes tested here SGLT2 inhibitors 1 open · Statins 1 open · mTOR inhibitors 10 · Tyrosine kinase inhibitors (TKIs) 4

Coming up

4phase 3 studies under way
26studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 30 Polycystic Kidney, Autosomal Dominant studies recruiting now, 8 (27%) set no upper age limit and 19 (63%) stop at 75 or younger. 7 (23%) take children under 18. 2 (7%) are for women only and 1 (3%) for men only; 9 (30%) take healthy volunteers.

Recruiting studies that take each age, of 30
AgeWomenMen
104 (13%)4 (13%)
1828 (93%)26 (87%)
3027 (90%)26 (87%)
4025 (83%)24 (80%)
5023 (77%)23 (77%)
6518 (60%)18 (60%)
7512 (40%)12 (40%)
859 (30%)9 (30%)

Across all 185 studies, recruiting or not: 61% stop at 75 or younger and 51% at 65; 16% take children; 2% are for women only and 1% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Polycystic Kidney, Autosomal Dominant studies take

Of 17 phase 2 interventional studies under Polycystic Kidney, Autosomal Dominant, half reached primary completion within 39 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 239 mo18–53 · 17 studies——
Interventional, no phase30 mo19–54 · 23 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 15, 2026.

Started recruiting1

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 185. Browse all 185 → or search them.