Hyperuricemia clinical trials
The registry lists 240 studies for Hyperuricemia across more than 10 countries. 44 are recruiting or about to start. 111 of them are mainly about Hyperuricemia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Status
Who runs them
Jiangsu HengRui Medicine Co., Ltd. (14) · LG Chem (10) · Sanofi (8) · Takeda (7) · Arthrosi Therapeutics (6) · Sun Yat-sen University (6) · Allena Pharmaceuticals (5) · Assiut University (5)
What is being tested here
Drugs under test in Hyperuricemia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare · Phase 3 · Olatec Therapeutics, Inc.
- Feb 2027Combined Metabolic Activator Supplementation in Subjects Diagnosed With Gout · Phase 3 · ScandiBio Therapeutics AB
- Nov 2027A Study of Dotinurad Versus Allopurinol in Participants With Gout · Phase 3 · Crystalys Therapeutics
- Nov 2026Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients · Arthrosi Therapeutics
- Nov 2026Comparison of the Effect of Allopurinol Versus Febuxostat on Serum Uric Acid in Patients With Chronic Kidney Disease Associated With Hyperuricemia · Nishtar Medical University
- Dec 2026Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) · Wake Forest University Health Sciences
- Dec 2026Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model · Örebro University, Sweden
- Dec 2026The Effects of a Probiotic Food Supplement in Hyperuricaemia · Örebro University, Sweden
- Dec 2026Safety, Tolerability, and Pharmacokinetic Characteristics of SSS11 in Patients With Gout and Hyperuricemia · Shenyang Sunshine Pharmaceutical Co., LTD.
- Jan 2027A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia · Novo Nordisk A/S
Who these studies take
Of the 29 Hyperuricemia studies recruiting now, 8 (28%) set no upper age limit and 13 (45%) stop at 75 or younger. 1 (3%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (21%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (3%) | 1 (3%) |
| 18 | 25 (86%) | 25 (86%) |
| 30 | 26 (90%) | 26 (90%) |
| 40 | 28 (97%) | 28 (97%) |
| 50 | 28 (97%) | 28 (97%) |
| 65 | 28 (97%) | 28 (97%) |
| 75 | 21 (72%) | 21 (72%) |
| 85 | 9 (31%) | 9 (31%) |
Across all 240 studies, recruiting or not: 62% stop at 75 or younger and 36% at 65; 5% take children; 1% are for women only and 8% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperuricemia studies take
Of 31 phase 1 interventional studies under Hyperuricemia, half reached primary completion within 6 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 6 mo1–10 · 31 studies | 4 mo1–9 · 29 studies | — |
| Phase 2 | 14 mo10–26 · 24 studies | — | — |
| Interventional, no phase | 14 mo6–34 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
- Combined Metabolic Activator Supplementation in Subjects Diagnosed With GoutOct 22, 2026NCT07889284
- Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity RisksOct 21, 2026NCT07884903
Studies
Recruiting first, then most recently updated. Showing 50 of 240. Browse all 240 → or search them.
- A Study of Dotinurad Versus Allopurinol in Tophaceous GoutRecruitingNCT07089888Phase 31 country
- A Study of Dotinurad Versus Allopurinol in Participants With GoutRecruitingNCT07089875Phase 33 countries
- Combined Metabolic Activator Supplementation in Subjects Diagnosed With GoutNot yet recruitingNCT07889284Phase 31 country
- Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity RisksNot yet recruitingNCT078849031 country
- A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)RecruitingNCT07280156Phase 23 countries
- Mazdutide for Weight Management and Gout in Adults With ObesityNot yet recruitingNCT07824895Phase 4
- SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) TrialRecruitingNCT06674109Phase 41 country
- A Study of IN026 in Participants With Refractory GoutRecruitingNCT07587684Phase 11 country
- Evaluation of the Effect of Hyperuricemia on Alveolar Bone LossRecruitingNCT076661261 country
- A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult SubjectsEnrolling by invitationNCT07324434Phase 11 country
- Tart Cherry Citrate Effervescent Tablet for Urate-Lowering Therapy in Participants With Asymptomatic HyperuricemiaRecruitingNCT07613138Not applicable1 country
- Study on the Effects and Mechanisms of Probiotic Supplementation in Ameliorating Uric Acid Metabolism in Asymptomatic Hyperuricemic IndividualsNot yet recruitingNCT07650214Not applicable1 country
- Probiotic-Uricase Complex Preparation for Improving Uric Acid Metabolism in Patients With HyperuricemiaNot yet recruitingNCT07613164Not applicable
- The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and HyperuricemiaRecruitingNCT07362355Phase 21 country
- The Effects of a Probiotic Food Supplement in HyperuricaemiaRecruitingNCT07141888Not applicable1 country
- Clinical Trial of BR2251 Tablets for Patients With Primary Gout and HyperuricemiaNot yet recruitingNCT07498647Phase 2
- Chronic Kidney Disease and Metabolic Disorders in the ElderlyNot yet recruitingNCT074945261 country
- Study of Dapansutrile Tablets in Subjects With an Acute Gout FlareRecruitingNCT05658575Phase 2/35 countries
- Prospective Exploratory Study on the Comprehensive Application Effectiveness of Exercise Prescription Decision Support Tools in the Management of Patients With "Four Highs" (Hypertension, Hyperglycemia, Hyperlipidemia, Hyperuricemia)RecruitingNCT07400549Not applicable1 country
- A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney DiseaseRecruitingNCT06310967Phase 1/22 countries
- HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-EffectivenessNot yet recruitingNCT07369622Phase 4
- Effect of Dotinurad in Hyperuricemia With HypertensionRecruitingNCT06834230Phase 41 country
- Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)RecruitingNCT047522931 country
- Hyperuricemia as Early Indication of CKD Progressing in PrediabeticNot yet recruitingNCT07199205
- Is There a Relationship Between Uric Acid Level and Liver Fibrosis in Obese PatientsNot yet recruitingNCT07168551
- This Study is to Estimate the Efficacy of Hemodialysis Alone for Uric Acid Clearance in Patients on Hemodialysis. In Order to Evaluate the Need of Adjuvant Uric Acid Lowering TherapyRecruitingNCT071443321 country
- Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation ModelRecruitingNCT069816631 country
- Clinical Efficacy Trial of Burdock Root Extract in Patients With Asymptomatic HyperuricaemiaRecruitingNCT07002762Not applicable1 country
- Developing A Gout Action Plan in Primary Care Setting in SingaporeNot yet recruitingNCT07061587Not applicable1 country
- Metabolically Healthy Obesity Increases the Risks of MASLD and HyperuricemiaEnrolling by invitationNCT070018651 country
- Safety, Tolerability, and Pharmacokinetic Characteristics of SSS11 in Patients With Gout and HyperuricemiaRecruitingNCT06629376Phase 11 country
- Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release TabletsRecruitingNCT06966635Phase 41 country
- Manual Acupuncture (MA) for Asymptomatic Hyperuricemia (HUA)RecruitingNCT06824376Not applicable1 country
- Osaka Cardiometabolic Epidemiological Study: Ohtori Study Part 2RecruitingNCT066940121 country
- GOS and the Management of HyperuricemiaRecruitingNCT06630377Not applicable1 country
- Screening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University HospitalNot yet recruitingNCT06586229
- CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep ApneaRecruitingNCT06463561Phase 41 country
- Prebiotics and the Management of HyperuricemiaRecruitingNCT06420401Not applicable1 country
- Efficacy Study of Acupuncture on Asymptomatic HyperuricemiaRecruitingNCT05406830Not applicable1 country
- Impact of Hyperuricemia on Psoriatic ArthritisRecruitingNCT061254441 country
- Prediction of UA/SOD Ratio as a Biomarker of Oxidative Stress in Atrial FibrillationRecruitingNCT061198021 country
- Probiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical TrialRecruitingNCT04199325Not applicable1 country
- Efficacy and Safety of Kui-Yuan Chewable Tablets in Patients With HyperuricemiaNot yet recruitingNCT05913310Phase 4
- Risk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic DiseasesRecruitingNCT054766271 country
- Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD)Active, not recruitingNCT070537091 country
- A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic HyperuricemiaActive, not recruitingNCT06859073Phase 11 country
- Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy SubjectsActive, not recruitingNCT07366749Not applicable1 country
- Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-302)CompletedNCT06439602Phase 35 countries
- Comparison of the Effect of Allopurinol Versus Febuxostat on Serum Uric Acid in Patients With Chronic Kidney Disease Associated With HyperuricemiaActive, not recruitingNCT07850713Not applicable1 country
- Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301)CompletedNCT06846515Phase 31 country