Drug
Tizanidine clinical trials
Also written Zanaflex.
- studies test it
- 30
- open now
- 9
- in phase 3
- 4
- first study started
- 2001
Keep track of what changes. Save the tizanidine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Combined with it in one product
Studies by the year they started
30 studies that test it; most in 2024 (5)
| Year | Studies |
|---|---|
| 2001 | 2 |
| 2002 | 1 |
| 2003 | 1 |
| 2006 | 2 |
| 2008 | 1 |
| 2011 | 1 |
| 2013 | 3 |
| 2016 | 1 |
| 2017 | 1 |
| 2020 | 2 |
| 2022 | 2 |
| 2023 | 3 |
| 2024 | 5 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 7
- Phase 2
- 5
- Phase 3
- 4
- Phase 4
- 7
- No phase
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 20
Teva GTC (3) · Acorda Therapeutics (2) · Dr. Reddy's Laboratories Limited (2) · Second Affiliated Hospital, School of Medicine, Zhejiang University (2) · University of Mississippi Medical Center (1) · Primus Pharmaceuticals (1) · Uşak University (1) · Mansoura University (1)
Often tested with
Tested in the same studies.
Baclofen (2) · Gabapentin (1) · Metaxalone (1) · Vemurafenib (1) · Bupivacaine (1) · Botulinum toxin type A (1) · Pregabalin (1) · Celecoxib (1)
Studies
Open first, then newest update. How each study uses tizanidine is read from its arms, and is right about nine times in ten.
Testing it · 30
- Effect of Neural Constraints on Movement in StrokeRecruitingEarly Phase 1Northwestern UniversityNCT06666673Written as Tizanidine
- Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot StudyRecruitingPhase 2Hartford HospitalNCT07766837Written as Tizanidine
- The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep QualityRecruitingNot applicableTanta UniversityNCT07800364Written as Tizanidine
- Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PKRecruitingEarly Phase 1Indiana UniversityNCT05789173Written as Methadone and Tizanidine
- CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery TrialRecruitingPhase 3Stanford UniversityNCT06027099Written as Tizanidine
- Efficacy and Safety of Pregabalin/Tizanidine vs. Pregabalin in Patients With FibromyalgiaNot yet recruitingNot applicableBeijing Tiantan HospitalNCT07382921Written as Pregabalin with tizanidine
- TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME）RecruitingPhase 3Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT05484349Written as Tizanidine Hydrochloride
- Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized TrialNot yet recruitingPhase 4Sultan Qaboos UniversityNCT06303076Written as Tizanidine Hcl 4Mg Tab
- Clinical Study on the Effect of Tizanidine on the Function and Pain of Patients After Shoulder ArthroscopyNot yet recruitingEarly Phase 1Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT05852093Written as Celecoxib+Buprenorphine Transdermal Patch+Tizanidine
- Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and CognitionCompletedPhase 4Primus PharmaceuticalsNCT06382662Written as tizanidine 8mg
- Electrical Neuromodulation for Modifying Spinal Network Involved in SpasticityActive, not recruitingNot applicableUniversity of Mississippi Medical CenterNCT07792616Written as Tizanidine
- Tizanidine and Acoustic ReflexCompletedNot applicableUşak UniversityNCT07309354Written as Tizanidine
- Bi-level Erector Spinae Plane Block and Pre-emptive Oral Tizanidine for Analgesia After Mastectomy SurgeryCompletedNot applicableMansoura UniversityNCT07022353Written as tizanidine oral capsule
- Comparison of Analgesic Efficacy of Intrathecal Levobupivacaine With and Without Oral Tizanidine in Lower Limb Surgeries: A Prospective Randomized StudyCompletedPhase 4All India Institute of Medical SciencesNCT07310628Written as Tizanidine
- Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous SuspensionCompletedPhase 3Endeavor HealthNCT06258785Written as Tizanidine
- Gabapentin and Tizanidine for Insomnia in Chronic PainCompletedPhase 2University of California, San DiegoNCT04429347Written as Tizanidine
- A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG TrialCompletedPhase 2Acorda TherapeuticsNCT01839279Written as Tizanidine
- Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee ArthroplastyStatus unknownNot applicableRothman Institute OrthopaedicsNCT04574791Written as TiZANidine 2 MG Oral Capsule
- Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back PainCompletedPhase 4Montefiore Medical CenterNCT03068897Written as Tizanidine
- A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic MalignanciesCompletedPhase 1Hoffmann-La RocheNCT01844674Written as Tizanidine
See all 30 studies that test tizanidine →
Given in every arm · 2 — tizanidine is usual care beside what is tested
As the comparator · 2 — what is tested is compared with tizanidine
- Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back PainWithdrawnPhase 2Sun Pharma Advanced Research Company LimitedNCT02887534Written as Reference1401 (Tizanidine)
- Study to Assess the Efficacy and Safety of Tizaspray® Versus Sirdalud®, in Patients With Acute Low Back PainCompletedPhase 3MDM S.p.A.NCT02934061Written as Sirdalud® 2 mg tablets administered
Codes
What other systems call tizanidine · ClinicalTrials.gg INT002774
- MeSH (NLM) C023754tizanidineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6AI06C00GWTIZANIDINEConfirmed FDA, NLM, Wikidata
- RxNorm 57258Confirmed FDA, Wikidata
- Wikidata Q423538tizanidineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61976TizanidineOne source FDA
- DrugBank DB00697One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C023754 | tizanidine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6AI06C00GW | TIZANIDINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 57258 | — | Confirmed FDA, Wikidata |
| Wikidata | Q423538 | tizanidine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61976 | Tizanidine | One source FDA |
| DrugBank | DB00697 | — | One source Wikidata |
Also registered as tizanidine hydrochloride (UNII B53E3NMY5C · RxNorm 236460).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.