Drug
Chloroprocaine clinical trials
Also written Nesacaine and Iheezo.
Keep track of what changes. Save the chloroprocaine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
29 studies that test it; most in 2019 (6)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 1 |
| 2013 | 1 |
| 2015 | 3 |
| 2016 | 3 |
| 2017 | 1 |
| 2018 | 2 |
| 2019 | 6 |
| 2020 | 1 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 3 |
| 2025 | 1 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Pain
- 1
Who runs them
Industry 8 · Other 21
Sintetica SA (6) · Harrow Inc (2) · Oregon Health and Science University (2) · Duke University (2) · Retina Consultants of Delmarva (1) · Montefiore Medical Center (1) · Columbia University (1) · Tufts Medical Center (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses chloroprocaine is read from its arms, and is right about nine times in ten.
Testing it · 29
- Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under AnesthesiaRecruitingPhase 4Duke UniversityNCT07348614Written as Chloroprocaine
- Local Anesthetic Clinical TrialEnrolling by invitationPhase 4Baylor Research InstituteNCT07601750Written as Chlorprocaine
- Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal InjectionsEnrolling by invitationPhase 4Harrow IncNCT07456826Written as Chloroprocaine Ophthalmic Gel 3% (IHEEZO)
- Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee ArthroplastyNot yet recruitingPhase 4Nova Scotia Health AuthorityNCT07239999Written as Chloroprocaine Injection
- Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean SectionRecruitingNot applicableAretaieion University HospitalNCT06376058Written as Chloroprocaine 1% Injectable Solution
- Multicenter Study of Chloroprocaine Versus Ropivacaine for Epidural Labor AnalgesiaNot yet recruitingPhase 4Women's Hospital School Of Medicine Zhejiang UniversityNCT06472232Written as Chloroprocaine
- Patient Comfort Following Intravitreal Injections Using Iheezo Versus Standard AnesthesiaCompletedPhase 4Retina Consultants of DelmarvaNCT07779356Written as Iheezo
- The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric PopulationCompletedPhase 2Sintetica SANCT03918798Written as Chloroprocaine 1% Injectable Solution
- Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric PopulationCompletedPhase 3Sintetica SANCT05926258Written as Chloroprocaine 3% eye gel
- The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-IodineCompletedPhase 4Harrow IncNCT05934253Written as Chloroprocaine ophthalmic gel 3%
- 1% Chloroprocaine(PF) vs. Bupivacaine SpinalsCompletedPhase 2Montefiore Medical CenterNCT03324984Written as 1% chloroprocaine
- Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean DeliveryCompletedEarly Phase 1Oregon Health and Science UniversityNCT03760718Written as Preservative free 1% Chloroprocaine
- Comparison of Clorotekal and Bupivacaine for Short Obstetric SurgerySuspendedPhase 4Oregon Health and Science UniversityNCT03967288Written as Chloroprocaine Injection [Clorotekal]
- Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean SectionTerminatedPhase 3Sintetica SANCT02919072Written as Chloroprocaine
- Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.CompletedPhase 3Sintetica SANCT04685538Written as Chloroprocaine 3%
- Chloroprocaine Spinal for Outpatient Knee SurgeryTerminatedPhase 2Hospital for Special Surgery, New YorkNCT03365752Written as Chloroprocaine
- Optimizing Anesthesia for Post Partum Tubal LigationsTerminatedPhase 2University of Alabama at BirminghamNCT03993314Written as Chloroprocaine
- ED90 of 3% Chloroprocaine for Cervical CerclageCompletedPhase 4Duke UniversityNCT03805438Written as Chloroprocaine Hcl 3% Inj
- Intraabdominal Chloroprocaine During Cesarean Delivery for Pain ControlWithdrawnPhase 3Johns Hopkins UniversityNCT03260972Written as Chloroprocaine Hcl 2% Inj
- Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve BlockCompletedPhase 3Sintetica SANCT02385097Written as Chloroprocaine HCl 2%
See all 29 studies that test chloroprocaine →
Given in every arm · 4 — chloroprocaine is usual care beside what is tested
- Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block ApproachesNot yet recruitingPhase 4Duke UniversityNCT07444827Written as Chloroprocaine Injection
- Efficacy of Intravenous Dexamethasone in Prolonging the Duration of Spinal Anesthesia With Chloroprocaine in Knee ArthroscopyNot yet recruitingPhase 3CMC Ambroise ParéNCT07674576Written as Chloroprocaine Injection [Clorotekal]
- Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee ProceduresCompletedPhase 2Sintetica SANCT03428230Written as NIMP: Chloroprocaine HCl 1% (10 mg/mL), solution for injection
- Decision Support for Intraoperative Low Blood PressureCompletedNot applicableVanderbilt University Medical CenterNCT02726620Written as Chloroprocaine
As the comparator · 1 — what is tested is compared with chloroprocaine
Codes
What other systems call chloroprocaine · ClinicalTrials.gg INT002296
- MeSH (NLM) C004616chloroprocaineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 5YVB0POT2HCHLOROPROCAINEConfirmed FDA, NLM, Wikidata
- RxNorm 20859Confirmed FDA, Wikidata
- Wikidata Q2964133chloroprocaineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C72168ChloroprocaineOne source FDA
- DrugBank DB01161One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C004616 | chloroprocaine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 5YVB0POT2H | CHLOROPROCAINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 20859 | — | Confirmed FDA, Wikidata |
| Wikidata | Q2964133 | chloroprocaine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C72168 | Chloroprocaine | One source FDA |
| DrugBank | DB01161 | — | One source Wikidata |
Also registered as chloroprocaine hydrochloride (UNII LT7Z1YW11H · RxNorm 53616).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.