Drug
Benzocaine clinical trials
Also written AR01.
- studies test it
- 18
- open now
- 1
- in phase 3
- 5
- first study started
- 2007
Keep track of what changes. Save the Benzocaine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
- AR01
- 3
Combined with it in one product
Studies by the year they started
18 studies that test it; most in 2013 (3)
| Year | Studies |
|---|---|
| 2007 | 1 |
| 2011 | 2 |
| 2012 | 2 |
| 2013 | 3 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 2
- Phase 2
- 5
- Phase 3
- 5
- Phase 4
- 4
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
- Pain
- 1
Who runs them
Industry 9 · Other 9
Arbor Pharmaceuticals, Inc. (3) · Cetylite Industries (2) · Vanderbilt University Medical Center (1) · TC Erciyes University (1) · Mohammed Bin Rashid University of Medicine and Health Sciences (1) · B.P. Koirala Institute of Health Sciences (1) · EMS (1) · McNeil AB (1)
Often tested with
Tested in the same studies.
Lidocaine (2) · Anesthetics (1) · Polymyxin B (1) · Prednisolone (1) · Clioquinol (1)
Studies
Open first, then newest update. How each study uses Benzocaine is read from its arms, and is right about nine times in ten.
Testing it · 18
- Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric PatientsNot yet recruitingNot applicableGovernment Dental College and Hospital, IndiaNCT07682181Written as Topical Benzocaine 20%
- Role of the Foregut in Nutrient Metabolism in Lean and Obese HumansCompletedPhase 1Vanderbilt University Medical CenterNCT02537314Written as benzocaine
- Intrauterine Device Insertion Pain ManagementTerminatedPhase 4University of Missouri-ColumbiaNCT06951191Written as Benzocaine 20%
- Effects of Topical Lidocaine and Benzocaine on Pain Level and Injection SatisfactionCompletedPhase 3TC Erciyes UniversityNCT07242157Written as Benzocaine spray
- Effect of Benzocaine 20% Topical Anesthesia on Pain Levels When Placing Separators in Children Receiving Hall Technique CrownsCompletedEarly Phase 1Mohammed Bin Rashid University of Medicine and Health SciencesNCT06272903Written as 20% benzocaine, topical anesthetic
- Pre Injection Use of Cryoanesthesia Versus Topical Anesthetic Gel in Reducing Pain Perception During Palatal InjectionsCompletedPhase 4B.P. Koirala Institute of Health SciencesNCT06165432Written as Topical Benzocaine
- Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local Anaesthetic InjectionsStatus unknownNot applicableMinia UniversityNCT05564442Written as 20% benzocaine gel
- Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis EczematousCompletedPhase 3EMSNCT01429701Written as polymyxin B sulphate + prednisolone + benzocaine + clioquinol
- Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal VolunteersCompletedPhase 2Cetylite IndustriesNCT03233737Written as One spray CTY-5339-A
- Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal VolunteersCompletedPhase 2Cetylite IndustriesNCT02908620Written as One spray CTY-5339-A
- A Study to Determine the Efficacy and Safety of a Benzocaine Lozenge for Treatment of Sore Throat.CompletedPhase 3McNeil ABNCT03432923Written as Benzocaine 8 mg
- Benzocaine Versus Placebo Spray for Pain Relief at HysterosalpingogramCompletedPhase 4University of PennsylvaniaNCT01925469Written as Benzocaine
- Study to Compare Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media (AR01007)TerminatedPhase 3Arbor Pharmaceuticals, Inc.NCT02074007Written as AR01
- Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis MediaCompletedPhase 2Otic Therapy, LLCNCT02092454Written as Benzocaine
- Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis MediaCompletedPhase 2Arbor Pharmaceuticals, Inc.NCT01588535Written as benzocaine
- Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis MediaCompletedPhase 3Arbor Pharmaceuticals, Inc.NCT02044341Written as AR01
- Benzocaine Gel Toothache Dose-Response StudyCompletedPhase 4Wyeth is now a wholly owned subsidiary of PfizerNCT00474175Written as benzocaine
- Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the NewbornTerminatedPhase 1/2Tel-Aviv Sourasky Medical CenterNCT01274247Written as Topical Benzocaine
Given in every arm · 2 — Benzocaine is usual care beside what is tested
- Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler InjectionsTerminatedPhase 4Galderma R&DNCT00716443Written as benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Decision Support for Intraoperative Low Blood PressureCompletedNot applicableVanderbilt University Medical CenterNCT02726620Written as Benzocaine
As the comparator · 8 — what is tested is compared with Benzocaine
- Photobiomodulation and Tooth AnalgesiaRecruitingNot applicableUniversity of Maryland, BaltimoreNCT06691269Written as Topical Benzocaine
- Pain Reduction Using Vibration and Topical AnesthesiaCompletedEarly Phase 1University of LahoreNCT06804616Written as 20% benzocaine Gel
- Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia InjectionStatus unknownNot applicableAliaa HamoudaNCT05861154Written as Benzocaine Gel
- Emla Cream Versus Benzocaine on AnalgesiaCompletedEarly Phase 1Dow University of Health SciencesNCT05060913Written as Benzocaine Gel
- Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental PatientsCompletedPhase 2Nourhan M.AlyNCT03790540Written as Topical Benzocaine 20%
- Comparison of Two Topical Anesthetics: Benzocaine Versus PliaglisCompletedPhase 4University of MichiganNCT01951820Written as Benzocaine
- EMLA Topical Anesthetic During Scaling and Root PlaningCompletedNot applicableFranciscan University CenterNCT01860235Written as 2% Benzocaine
- Comparative Efficacy of 20% Benzocaine Versus TAC Alternate GelStatus unknownPhase 4The University of Texas Health Science Center, HoustonNCT00846690Written as benzocaine
Codes
What other systems call Benzocaine · ClinicalTrials.gg INT007059
- MeSH (NLM) D001566BenzocaineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) U3RSY48JW5BENZOCAINEConfirmed FDA, NLM, Wikidata
- RxNorm 1399Confirmed FDA, Wikidata
- Wikidata Q422745benzocaineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C28923BenzocaineOne source FDA
- DrugBank DB01086One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001566 | Benzocaine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | U3RSY48JW5 | BENZOCAINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1399 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422745 | benzocaine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C28923 | Benzocaine | One source FDA |
| DrugBank | DB01086 | — | One source Wikidata |
Also registered as benzocaine hydrochloride (UNII OG625Z9LEO · RxNorm 1049105).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.