Unconsciousness clinical trials
The registry lists 60 studies for Unconsciousness across more than 10 countries. 9 are recruiting or about to start. 31 of them are mainly about Unconsciousness (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-02. Counting its 5 narrower conditions too, such as Syncope: 584 studies, 122 open.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
General Hospital of Ningxia Medical University (2) · Gangnam Severance Hospital (2) · Regional Hospital Liberec (2) · Cairo University (1) · Universidad del Desarrollo (1) · University Hospital, Basel, Switzerland (1) · University Hospital Freiburg (1) · Baskent University Ankara Hospital (1)
What is being tested here
Drugs under test in Unconsciousness studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 0 | 0 | 3 |
| Propofol | 0 | 0 | 3 |
| Midazolam | 0 | 0 | 3 |
| Ketamine | 0 | 0 | 2 |
| Sevoflurane | 0 | 0 | 2 |
| Remifentanil | 0 | 0 | 2 |
| Acetylcysteine | 0 | 0 | 1 |
| Sufentanil | 0 | 0 | 1 |
| Esketamine | 0 | 0 | 1 |
| Zoledronic Acid | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026External Nitric Oxide Measurement Through SNO Degradation · Indiana University
- Feb 2027HemodynamIc eFfects of Lung Collapse and overdIstension During ARDS · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Who these studies take
Of the 5 Unconsciousness studies recruiting now, 1 (20%) set no upper age limit and 2 (40%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (60%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (80%) | 4 (80%) |
| 30 | 4 (80%) | 4 (80%) |
| 40 | 4 (80%) | 4 (80%) |
| 50 | 4 (80%) | 4 (80%) |
| 65 | 4 (80%) | 4 (80%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 60 studies, recruiting or not: 38% stop at 75 or younger and 30% at 65; 15% take children; 3% are for women only and 3% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Unconsciousness studies take
Of 16 interventional studies with no phase under Unconsciousness, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo4–40 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 60. Browse all 60 → or search them.
- Screening Emotions in Adolescents at the Hospital for mTBIRecruitingNCT063705201 country
- The Effect of Auditory Stimulation and the "Love Glove" TechniqueNot yet recruitingNCT07602998Not applicable1 country
- HemodynamIc eFfects of Lung Collapse and overdIstension During ARDSNot yet recruitingNCT07423520Not applicable1 country
- External Nitric Oxide Measurement Through SNO DegradationEnrolling by invitationNCT04903535Not applicable1 country
- Developing Strategies to Facilitate Consent of Legally Authorized Representatives to Clinical TrialsRecruitingNCT06471400Not applicable1 country
- Analysis of Deep Brain Nuclei LFP and Cortical EEG Signals During the Recovery From General AnesthesiaRecruitingNCT064009011 country
- Incidence of Episodes of (Dis)Connected Consciousness Among Emergency Patients Admitted in the Resuscitation RoomRecruitingNCT063625251 country
- SeeMe: An Automated Tool to Detect Early Recovery After Brain InjuryRecruitingNCT060834411 country
- A New Approach in Intensive Care Unit Consciousness Assessment: FIVE ScoreNot yet recruitingNCT060367321 country
- Brain Networks and ConsciousnessTerminatedNCT045025501 country
- Intubation Checklist in the Intensive Care UnitCompletedNCT067913171 country
- Changes of Ciprofol Dosage and Bispectral Index Required for Loss of Consciousness in Patients of Different AgesCompletedNCT071485961 country
- Effectiveness of Familiar Voices and Nature Sounds Among Critically Ill Comatose PatientsCompletedNCT06470802Not applicable1 country
- Video-assisted First Aid by Young ChildrenCompletedNCT07106697Not applicable1 country
- Investigating the Role and Electrophysiological Characteristics of the Human Claustrum Based on SEEGCompletedNCT06575413Not applicable1 country
- Applicability of Syncope Guidelines in CataluñaCompletedNCT01721369
- BAsel Syncope EvaLuation (BASEL IX) StudyActive, not recruitingNCT015483529 countries
- Prevention of Pressure Ulcer by Lateral Tilt Bed in Neurocritical CareTerminatedNCT04078477Not applicable1 country
- The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance TomographyCompletedNCT04235231Not applicable1 country
- Low-Intensity Focused Ultrasound on Individuals With Disorder of Consciousness of Traumatic Brain InjuryCompletedNCT04306601Not applicable1 country
- Detection and Classification of Levels of Consciousness Using Parietal EEG-fNIRS During AnesthesiaCompletedNCT051120421 country
- Head Computed Tomography for Predicting Neurological Outcome After Cardiac ArrestCompletedNCT039130651 country
- Nociception Monitoring in Intensive CareCompletedNCT06270264Not applicable1 country
- The Impact of Different Recovery Positions on the Perfusion of the Lower Forearm and ComfortCompletedNCT05587179Not applicable1 country
- Effect of Early Coma Arousal Therapy on Conscious Level Recovery and Cognition in Traumatic Brain InjuryCompletedNCT05521815Not applicable1 country
- Glucose Counterregulation in Long Standing Type 1 DiabetesCompletedNCT01474889Not applicable1 country
- UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness StudyCompletedNCT03284307Phase 41 country
- Measuring Depth of Unconsciousness at the End of Life Using Bispectral Index (BIS)CompletedNCT017684161 country
- Management of Transitory Loss of Consciousness and Syncopes in the Emergency DepartmentStatus unknownNCT055759341 country
- Chinese Validation of the Simplified Evaluation of CONsciousness Disorders(SECONDs)CompletedNCT05496985Not applicable1 country
- Strategy + RehaCom for Memory Rehabilitation in Traumatic Brain Injury (TBI)Status unknownNCT04239456Not applicable1 country
- Pacemaker Effect With Closed Loop Sensor in Neuromodulated Syncope Refractory to Medical TherapyCompletedNCT03876652Not applicable1 country
- Nociception-Level (NOL) for the Assessment of Pain in Patient Unable to Self-ReportCompletedNCT045816421 country
- Livestreaming From Smartphones as a Supplement to Emergency CallsCompletedNCT040611871 country
- Remimazolam Bolus for General AnesthesiaCompletedNCT04901871Phase 31 country
- The Electroencephalogram and Clinical Effect of KetamineTerminatedNCT03679390Not applicable1 country
- Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Syncopation and SeizureStatus unknownNCT048791471 country
- A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 DiabetesCompletedNCT02206152Phase 1/21 country
- Race-Specific Propofol Titration to Effect for Procedural SedationCompletedNCT032908591 country
- Memory Priming in General AnesthesiaCompletedNCT03727464Not applicable1 country
- Suitability of Unobtrusive Bed Monitoring and Wrist-worn Heart Rate Monitor for Patient MonitoringCompletedNCT035727511 country
- Comparison of Three Methods for NG Tube PlacementCompletedNCT03699306Not applicable1 country
- A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain InjuryTerminatedNCT02589223Not applicable1 country
- Diagnostic Value of Arterial Blood Gas Analysis in Prehospital PatientsCompletedNCT030066921 country
- Volume Kinetics for 20% Albumin in Different Clinical SituationsStatus unknownNCT02556580Phase 41 country
- Airway Collapse in Patients With Mounier-Kuhn Syndrome: Titration With Positive Pressure to Reduce CollapseStatus unknownNCT03101059Not applicable1 country
- Sufentanil Bispectral Index ElderlyCompletedNCT02831101Not applicable
- Early Versus Late Intubation Trial in Physician Manned Emergency Medical ServicesWithdrawnNCT01730001Not applicable1 country
- The Neural Mechanisms of Anesthesia and Human Consciousness (Part 6)CompletedNCT02624401Phase 41 country
- The Effects of Different Doses of Dexmedetomidine on Propofol Requirement for Loss of Consciousness Undergoing Bispectral Index: a Double-blinded, Placebo-controlled TrialCompletedNCT02783846Not applicable