An observational study in Unconsciousness, Apnea, Postanesthetic and Sedative Overdose, sponsored by University of Florida. Completed at 1 site in United States. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-10-25.
Sponsored by University of Florida · Observational
Prospectively evaluate newly established guidelines and make clinicians aware of inter-racial difference in propofol sensitivity.
The primary motivation in conducting this study is to conduct the implementation science, i.e., formalize and train, and retrain if needed, anesthesia providers in the standard practice of titrating infusion rate to effect and clinically evaluate the effect of race and ethnicity on propofol monotherapy sedation during GI endoscopy. The ultimate goal is to make it less likely that patients from races known to be sensitive to propofol experience inadvertent overdosing.
60 studies on the registry are indexed under Unconsciousness; 9 are open to participants now.
This study's enrollment of 2,780 is above the median of 200 across 21 observational studies indexed under Unconsciousness.
Browse Unconsciousness studies →University of Florida is the lead sponsor of 1,287 studies on the registry; 199 are open to participants now.
Of its 180 completed or terminated interventional studies of FDA-regulated products, 143 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients undergoing propofol sedation at Gainesville (GNV) and Jacksonville (JAX) GI Endoscopy suites
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Exclusion Criteria:
Train anesthesia providers who deliver propofol sedation for GI endoscopy procedures to follow a uniform propofol monotherapy administration guideline to titrate propofol monotherapy infusion to effect according to a standardized protocol.
Procedure: Titrate propofol monotherapy infusion to effect
Compare the effectiveness of training intervention and standardized titration to effect through aggregate data for metrics of recovery times.
Train anesthesia providers in a standardized protocol for titrating propofol infusion to effect.
Change in the recovery times among races and ethnicities
Monitored using aggregate data for metrics of recovery times
Time frame: Change from baseline up to 24 hours
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2018 to primary completion in Feb 2019, 13 months.
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This study is completed, as verified in Oct 2019. You cannot join it, but the record below documents what was studied.
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