Thyroid Nodule clinical trials
The registry lists 207 studies for Thyroid Nodule across more than 10 countries. 64 are recruiting or about to start. 178 of them are mainly about Thyroid Nodule (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Assiut University (10) · The University of Hong Kong (5) · Theraclion (4) · Sohag University (3) · Umraniye Education and Research Hospital (3) · Inha University Hospital (3) · Chinese PLA General Hospital (3) · Bezmialem Vakif University (3)
What is being tested here
Drugs under test in Thyroid Nodule studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Inositol | 1 | 0 | 1 |
| Amoxicillin | 0 | 0 | 2 |
| Clavulanic Acid | 0 | 0 | 2 |
| Metformin | 0 | 0 | 2 |
| Ringer's Solution | 0 | 0 | 1 |
| Ketorolac | 0 | 0 | 1 |
| Calcitriol | 0 | 0 | 1 |
| Acetaminophen | 0 | 0 | 1 |
| Tramadol | 0 | 0 | 1 |
| Ethanol | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules · Royal Berkshire NHS Foundation Trust
- Dec 2026TRAIL Study: Feasibility and Pilot · Dartmouth-Hitchcock Medical Center
- Dec 2026Postoperative Hypocalcemia After Thyroidectomy · Minia University
- Dec 2026Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical Removal · Insel Gruppe AG, University Hospital Bern
- Dec 2026A Novel Ultrasound Probe for Thyroid Imaging and Machine Learning · Sound Blade Medical Inc.
- Jan 2027Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures · Cedars-Sinai Medical Center
- Mar 2027Myo-inositol and Selenium in Indeterminate Thyroid Nodules (TIR3a) · Regina Elena Cancer Institute
- Apr 2027Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry · Sarasota Memorial Health Care System
- Apr 2027Diagnostic Accuracy of Fine Needle Aspiration Cytology (FNAC) Compared to TI-RADS 3 in the Evaluation of Thyroid Nodules: A Prospective Study · Sohag University
- Apr 2027Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System · Pulse Biosciences, Inc.
Who these studies take
Of the 43 Thyroid Nodule studies recruiting now, 33 (77%) set no upper age limit and 5 (12%) stop at 75 or younger. 5 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 10 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (12%) | 5 (12%) |
| 18 | 40 (93%) | 40 (93%) |
| 30 | 43 (100%) | 43 (100%) |
| 40 | 43 (100%) | 43 (100%) |
| 50 | 43 (100%) | 43 (100%) |
| 65 | 43 (100%) | 43 (100%) |
| 75 | 41 (95%) | 41 (95%) |
| 85 | 37 (86%) | 37 (86%) |
Across all 207 studies, recruiting or not: 19% stop at 75 or younger and 7% at 65; 15% take children; 1% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Thyroid Nodule studies take
Of 71 interventional studies with no phase under Thyroid Nodule, half reached primary completion within 30 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 30 mo14–46 · 71 studies | — | 30 mo13–46 · 67 studies |
| Observational | 47 mo32–… · 38 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- NIRAF-Guided Parathyroid Identification During ThyroidectomyNov 6, 2026NCT07617584
Newly registered4
- Diagnostic Accuracy of Fine Needle Aspiration Cytology (FNAC) Compared to TI-RADS 3 in the Evaluation of Thyroid Nodules: A Prospective StudyNov 10, 2026NCT07928284
- Ultrasound-guided Microwave Ablation of Benign Thyroid NodulesOct 30, 2026NCT07906821
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerOct 30, 2026NCT07907432
- Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid SurgeryOct 28, 2026NCT07902349
Studies
Recruiting first, then most recently updated. Showing 50 of 207. Browse all 207 → or search them.
- Diagnostic Accuracy of Fine Needle Aspiration Cytology (FNAC) Compared to TI-RADS 3 in the Evaluation of Thyroid Nodules: A Prospective StudyEnrolling by invitationNCT07928284Not applicable1 country
- NIRAF-Guided Parathyroid Identification During ThyroidectomyRecruitingNCT07617584Not applicable1 country
- Thyroid Artery Embolization for the Treatment of Compressive Goiters.RecruitingNCT07360587Not applicable1 country
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerNot yet recruitingNCT079074321 country
- Ultrasound-guided Microwave Ablation of Benign Thyroid NodulesRecruitingNCT07906821Not applicable1 country
- Radiofrequency Ablation Study in LatinX PatientsRecruitingNCT05903196Not applicable1 country
- Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid SurgeryNot yet recruitingNCT07902349Not applicable1 country
- International PPB/DICER1 RegistryRecruitingNCT033821581 country
- Renovated Prediction Model for Difficult Transoral and Submental Endoscopic ThyroidectomyRecruitingNCT067388881 country
- Bethesda Classification and Risk Stratification in Differentiated Thyroid CarcinomaNot yet recruitingNCT07858097
- Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter RegistryEnrolling by invitationNCT068684591 country
- Postoperative Hypocalcemia After ThyroidectomyRecruitingNCT074280571 country
- Educational Videos for Thyroid Surgery PatientNot yet recruitingNCT07823543Not applicable
- Thyroid Health Outcomes Registry for SurgeryNot yet recruitingNCT07812779
- MWA vs RFA for the Treatment of Moderate-sized Benign Thyroid NodulesRecruitingNCT06426563Not applicable1 country
- A Novel Ultrasound Probe for Thyroid Imaging and Machine LearningRecruitingNCT07488585Not applicable1 country
- Myo-inositol and Selenium in Indeterminate Thyroid Nodules (TIR3a)RecruitingNCT06736015Not applicable1 country
- Percutaneous Thermo-ablation for the Treatment of Benign Thyroid NodulesRecruitingNCT072373731 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid NodulesRecruitingNCT036766471 country
- Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid NodulesRecruitingNCT072268041 country
- RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life StudyRecruitingNCT051893141 country
- Radiofrequency Ablation for BIII Thyroid NodulesRecruitingNCT051898081 country
- Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)RecruitingNCT067303211 country
- Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and Cytology Whole-Slide ImagesRecruitingNCT074883251 country
- Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid NodulesRecruitingNCT06423235Phase 41 country
- TRAIL Study: Feasibility and PilotRecruitingNCT06220656Not applicable1 country
- CEUS Improves the Diagnostic Performance of SRSS of Thyroid CarcinomaRecruitingNCT061467641 country
- The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid NodulesRecruitingNCT06340945Not applicable1 country
- Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid CancerRecruitingNCT047426081 country
- Active Surveillance for Bethesda IV Thyroid NodulesRecruitingNCT07370675Not applicable1 country
- Xiaojin Pill/Neixiao Luoli Pill for the Treatment of Thyroid NodulesNot yet recruitingNCT07340177Phase 41 country
- Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid NodulesRecruitingNCT07046546Not applicable1 country
- Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic ProceduresRecruitingNCT07299474Not applicable1 country
- A Study of Multiparametric Ultrasound Imaging MethodsRecruitingNCT07270237Not applicable1 country
- Microvascular Profiling of Nodules in the Thyroid GlandRecruitingNCT070413071 country
- Intravenous Sedation and Analgesia Versus Local Anesthesia During Microwave Ablation of Benign Thyroid NodulesNot yet recruitingNCT07235605Not applicable
- Decision Aid and Thyroid Nodules ManagementRecruitingNCT05264857Not applicable1 country
- Comparing a New 3D Technology Used to Measure Thyroid Nodule Volume to Standard UltrasoundEnrolling by invitationNCT07178080Not applicable1 country
- Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical RemovalRecruitingNCT07102264Not applicable1 country
- The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid CancerRecruitingNCT06929650Not applicable1 country
- 18F-FDG PET/TC in TIR3A E TIR3BEnrolling by invitationNCT068290431 country
- Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid NodulesRecruitingNCT067337531 country
- Ultrasound-guided Thermal Ablation for Benign Thyroid NodulesRecruitingNCT067297621 country
- Accuracy of FNAC in Diagnosis of Thyroid NodulesNot yet recruitingNCT06782828
- Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid PathologyRecruitingNCT067797471 country
- Active Surveillance Program in Thyroid NodulesNot yet recruitingNCT066532571 country
- Health-Related Quality of Life and Emotions in Patients with Thyroid NodulesRecruitingNCT066106041 country
- Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid NodulesNot yet recruitingNCT066071331 country
- Preoperative Hemogram Parameters and BRAF Molecular Test Detected by Bethesda 3 Cytology.RecruitingNCT065397021 country