Thyroid Neoplasms clinical trials
The registry lists 785 studies for Thyroid Neoplasms across more than 10 countries. 204 are recruiting or about to start. 501 of them are mainly about Thyroid Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Thyroid Nodule: 1,039 studies, 289 open.
ClinicalTrials.gov finds 1,288 studies for Thyroid Neoplasms. How that becomes 785 here
This page counts the studies the registry files under Thyroid Neoplasms, and those it files under no condition that list Thyroid Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,288Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −223Filed under a narrower condition, counted on its own pageThyroid Nodule 117 · Thyroid Cancer, Papillary 101 · Papillary Thyroid Microcarcinoma 2
- −118List Thyroid Neoplasms as a condition, but the registry did not file them under itMost often written as “Medullary Thyroid Cancer” (29), “Medullary Thyroid Carcinoma” (23), and “Anaplastic Thyroid Cancer” (20). The registry filed them under other conditions only, most often Carcinoma, Medullary (62) and Thyroid Carcinoma, Anaplastic (31).
- −162Match it another way50 name it in the title, 10 in a keyword, and 102 by a synonym or other text the search reads.
- 785The count on this page63 of them list Thyroid Neoplasms in their own words; the registry filed them under no condition.
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Status
Who runs them
National Cancer Institute (NCI) (41) · Memorial Sloan Kettering Cancer Center (23) · Fudan University (17) · Fujian Medical University (16) · M.D. Anderson Cancer Center (15) · Yonsei University (11) · Peking Union Medical College Hospital (11) · Assiut University (10)
What is being tested here
Drugs under test in Thyroid Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lenvatinib | 3 | 1 | 11 |
| Selpercatinib | 3 | 0 | 7 |
| Anlotinib | 3 | 0 | 5 |
| Dabrafenib | 2 | 0 | 7 |
| Thyroxine | 2 | 0 | 7 |
| Trametinib | 2 | 0 | 6 |
| Cyclophosphamide | 2 | 0 | 4 |
| Pralsetinib | 2 | 0 | 3 |
| Zanzalintinib | 2 | 0 | 2 |
| Becotatug vedotin | 2 | 0 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 16 open · Immune checkpoint inhibitors 5 open · Alkylating agents 2 open · Angiogenesis inhibitors 1 open · Antimitotic agents 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer · Phase 3 · Gustave Roussy, Cancer Campus, Grand Paris
- Jan 2027A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma · Phase 3 · Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Nov 2026Pembrolizumab in High-risk Thyroid Cancer · Istituti Clinici Scientifici Maugeri SpA
- Nov 2026A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation · Arvinas Inc.
- Dec 2026Predictive Value of microRNA in Thyroid Cytologies of Undetermined Type · Institut du Cancer de Montpellier - Val d'Aurelle
- Dec 2026The Safety, Dosimetry and Efficacy of 177Lu-INN805 in Patients With Malignant Solid Tumors · FindCure Biosciences (ZhongShan) Co., Ltd.
- Dec 2026Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer · University of Michigan Rogel Cancer Center
- Dec 2026TRAIL Study: Feasibility and Pilot · Dartmouth-Hitchcock Medical Center
- Dec 2026Patient-centered Dosage of Levothyroxine · University Hospital of North Norway
- Dec 2026Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine. · Assiut University
Who these studies take
Of the 152 Thyroid Neoplasms studies recruiting now, 96 (63%) set no upper age limit and 27 (18%) stop at 75 or younger. 37 (24%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 13 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 27 (18%) | 27 (18%) |
| 18 | 145 (95%) | 144 (95%) |
| 30 | 149 (98%) | 148 (97%) |
| 40 | 150 (99%) | 149 (98%) |
| 50 | 147 (97%) | 147 (97%) |
| 65 | 145 (95%) | 145 (95%) |
| 75 | 138 (91%) | 138 (91%) |
| 85 | 114 (75%) | 114 (75%) |
Across all 785 studies, recruiting or not: 18% stop at 75 or younger and 9% at 65; 17% take children; 2% are for women only and 1% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Thyroid Neoplasms studies take
Of 92 phase 2 interventional studies under Thyroid Neoplasms, half reached primary completion within 73 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 57 mo25–81 · 38 studies | — | — |
| Phase 1/2 | 36 mo28–81 · 21 studies | — | — |
| Phase 2 | 73 mo39–119 · 92 studies | — | 84 mo50–124 · 77 studies |
| Phase 3 | 38 mo30–106 · 19 studies | — | — |
| Interventional, no phase | 46 mo14–78 · 127 studies | — | 46 mo14–78 · 126 studies |
| Observational | 63 mo26–311 · 112 studies | — | 71 mo24–311 · 103 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting2
- Drug Repurposing in Thyroid Carcinoma: a Feasibility TrialOct 28, 2026NCT07485569
- Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid CancerOct 21, 2026NCT05468554
Results posted1
Stopped1
- Personalized Treatment in Thyroid DisordersSuspendedOct 22, 2026NCT03517579
Newly registered5
- Oral Mecobalamin for TKI-Associated Hand-Foot Syndrome in Advanced Thyroid CancerNov 3, 2026NCT07911891
- Head and Neck Cancer StrategiesNov 2, 2026NCT07909603
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerOct 30, 2026NCT07907432
- Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid CancerOct 21, 2026NCT07886905
- MRG003 Added to Ongoing Treatment After Progression in EGFR-Positive Advanced Thyroid CancerOct 14, 2026NCT07874321
Studies
Recruiting first, then most recently updated. Showing 50 of 785. Browse all 785 → or search them.
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid CancerNot yet recruitingNCT06991738Phase 1/21 country
- An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic TherapyRecruitingNCT04589624Phase 11 country
- The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid CancerRecruitingNCT04927416Phase 21 country
- Clinical and Genetic Studies in Familial Non-medullary Thyroid CancerRecruitingNCT011094201 country
- DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyRecruitingNCT012475971 country
- The Application of Electrical Stimulation in Postoperative Pain Management of Thyroid SurgeryRecruitingNCT06931743Not applicable1 country
- Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid CarcinomaRecruitingNCT07218315Not applicable1 country
- Studies on Tumors of the ThyroidRecruitingNCT000011601 country
- Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid CancerRecruitingNCT06359847Phase 21 country
- Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated ConditionsRecruitingNCT031602741 country
- Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before SurgeryRecruitingNCT06959511Phase 21 country
- Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsRecruitingNCT010056541 country
- Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid NodulesRecruitingNCT05229341Not applicable1 country
- Active Surveillance of Papillary Thyroid MicrocarcinomaRecruitingNCT02609685Not applicable1 country
- cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT053668811 country
- Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid CancerRecruitingNCT05999630Phase 31 country
- Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid CancerNot yet recruitingNCT079074321 country
- Head and Neck Cancer StrategiesEnrolling by invitationNCT079096031 country
- The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid CancerRecruitingNCT03841617Phase 21 country
- Drug Repurposing in Thyroid Carcinoma: a Feasibility TrialRecruitingNCT07485569Phase 11 country
- International PPB/DICER1 RegistryRecruitingNCT033821581 country
- Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid CancerNot yet recruitingNCT07886905Phase 21 country
- Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid CancerRecruitingNCT05468554Phase 31 country
- Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid CancerRecruitingNCT05783323Phase 21 country
- A Study of Avutometinib and Defactinib in People With Thyroid CancerRecruitingNCT06007924Phase 21 country
- Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsRecruitingNCT06239194Phase 1/21 country
- A Real-World Study of Second-line Therapies Among Radioiodine-refractory Differentiated Thyroid Cancer (RAI-R DTC) PatientsNot yet recruitingNCT07770074
- MRG003 Added to Ongoing Treatment After Progression in EGFR-Positive Advanced Thyroid CancerRecruitingNCT07874321Phase 21 country
- Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive MalignanciesRecruitingNCT05786924Phase 1/210 countries
- Renovated Prediction Model for Difficult Transoral and Submental Endoscopic ThyroidectomyRecruitingNCT067388881 country
- A Study of Selpercatinib (LY3527723) in Participants With Rearranged During Transfection (RET)-Altered Cancers in IndiaNot yet recruitingNCT07822880Phase 41 country
- XL092 and Cemiplimab in BRAF WT Thyroid CancerRecruitingNCT06902376Phase 11 country
- DESTINY-PANTUMOUR04RecruitingNCT071240001 country
- Postoperative Hypocalcemia After ThyroidectomyRecruitingNCT074280571 country
- GETNE Registration of Thyroid CancerRecruitingNCT037653331 country
- Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.RecruitingNCT065078781 country
- Pattern and Surgical Outcome of Papillary Thyroid Cancer at Sohag University HospitalsNot yet recruitingNCT07823439
- Tracheal Replacement Using A Cryopreserved Aortic Allograft For R0 Resection In Locally Advanced Thyroid Cancer (TRITON 02 Tracheal Replacement In ThyrOid caNcer)Not yet recruitingNCT07823686Phase 21 country
- Educational Videos for Thyroid Surgery PatientNot yet recruitingNCT07823543Not applicable
- Radiofrequency Ablation Versus Hemithyroidectomy for Small Thyroid CancersRecruitingNCT06796348Not applicable1 country
- Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine DepartmentRecruitingNCT04104529Not applicable1 country
- Thyroid Health Outcomes Registry for SurgeryNot yet recruitingNCT07812779
- Lesion Dosimetry With Iodine-124 in Metastatic Thyroid CarcinomaRecruitingNCT03647358Phase 11 country
- Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After ThyroidectomyRecruitingNCT07707401Not applicable1 country
- The Safety, Dosimetry and Efficacy of 177Lu-INN805 in Patients With Malignant Solid TumorsRecruitingNCT07459283Early Phase 11 country
- Pre-Clinic Visit Online Education for Thyroid CancerNot yet recruitingNCT07690839Not applicable
- Safety and Efficacy of Cryoablation for Thyroid TumorsRecruitingNCT07776262Not applicable1 country
- Selective Coverage Versus Comprehensive Coverage Radiotherapy in Poorly Differentiated and Anaplastic Thyroid CancerRecruitingNCT07777536Phase 21 country
- Prevalence and Predictors of Incidental Thyroid Carcinoma in Patients With Graves' Disease Undergoing Thyroidectomy.RecruitingNCT070595071 country
- Pralsetinib DDI Study in Patients With Advanced or Metastatic Solid TumorsRecruitingNCT07704658Phase 41 country