Drug
Oxymetazoline clinical trials
Also written Afrin, AGN-199201 and Upneeq.
- studies test it
- 45
- open now
- 3
- in phase 3
- 6
- first study started
- 2002
Keep track of what changes. Save the Oxymetazoline studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Combined with it in one product
Studies by the year they started
45 studies that test it; most in 2014 (9)
| Year | Studies |
|---|---|
| 2002 | 1 |
| 2005 | 1 |
| 2007 | 4 |
| 2008 | 2 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 3 |
| 2014 | 9 |
| 2015 | 1 |
| 2016 | 2 |
| 2017 | 3 |
| 2018 | 6 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 2 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 9
- Phase 2
- 12
- Phase 3
- 6
- Phase 4
- 13
- No phase
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 21 · Other 24
Allergan (8) · Mayo Clinic (2) · Richard Cartabuke (2) · Egalet Ltd (2) · RDD Pharma Ltd (2) · Washington University School of Medicine (2) · University of South Florida (2) · Bayer (1)
Often tested with
Tested in the same studies.
Mometasone Furoate (3) · AGN-190584 (3) · Tetracaine (3) · Epinephrine (2) · Pseudoephedrine (2) · Lidocaine (2) · Ketorolac Tromethamine (2) · Ketorolac (2)
Studies
Open first, then newest update. How each study uses Oxymetazoline is read from its arms, and is right about nine times in ten.
Testing it · 45
- Upneeq vs. Lumify PtosisNot yet recruitingPhase 4Duke UniversityNCT07390578Written as Oxymetazoline 0.1% (Upneeq)
- Nasal Obstruction With Oxymetazoline and CorticosteroidsRecruitingPhase 2Washington University School of MedicineNCT06830109Written as Oxymetazoline Nasal Spray
- Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep ApneaRecruitingPhase 4University of South FloridaNCT02630121Written as Oxymetazoline Hydrochloride
- A Study to Learn More About How Well Oxymetazoline HCl 0.05% Nasal Gel Works and How Safe It Is in Healthy AdultsCompletedPhase 2BayerNCT07582328Written as Oxymetazoline HCl 0.05% nasal gel
- Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic RhinitisCompletedPhase 4Dr. Behcet Uz Children's HospitalNCT07593898Written as Oxymetazoline 0.05% nasal solution
- Steroid Treatment for Elimination of Rebound Obstruction From Intranasal DecongestantsTerminatedPhase 2Washington University School of MedicineNCT07168148Written as Oxymetazoline + Triamcinolone
- Oxymetazoline Drops for Acquired Blepharoptosis From SynkinesisCompletedPhase 3Milton S. Hershey Medical CenterNCT05945615Written as Oxymetazoline 0.1% (Pf) Oph Soln Ud
- The Role of Nasal Breathing for Perfomance in Elite Athletes.CompletedNot applicableSahlgrenska University HospitalNCT06480071Written as Oxymetazoline, 0.05% Nasal Spray
- Study of Mometasone Furoate Nasal Spray and Oxymetazoline Nasal Spray Given Together Once A Day To Treat Seasonal Allergic Rhinitis (P04500)CompletedPhase 2Organon and CoNCT00552110Written as OXY combination: mometasone furoate nasal spray (MFNS) and oxymetazoline nasal spray (OXY)
- The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye AppearanceCompletedPhase 4University of MiamiNCT04831047Written as Oxymetazoline hydrochloride 0.1% ophthalmic solution
- Intra-anal Oxymetazoline in Healthy Adult VolunteersStatus unknownPhase 1RDD Pharma LtdNCT03529487Written as Oxymetazoline
- A Study Comparing Oxymetazoline 1% Cream to RHOFADECompletedPhase 1Taro Pharmaceuticals USANCT05148689Written as Oxymetazoline hydrochloride Cream, 1%
- An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythema Associated With RosaceaCompletedPhase 3Padagis LLCNCT03352323Written as Oxymetazoline
- A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream"CompletedPhase 3Actavis Inc.NCT03954444Written as Oxymetazoline Hydrochloride
- Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus SurgeryCompletedPhase 4The University of Texas Health Science Center, HoustonNCT03228914Written as Oxymetazoline
- A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With PresbyopiaCompletedPhase 2AllerganNCT02780115Written as AGN-199201 ophthalmic solution
- A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With PresbyopiaCompletedPhase 2AllerganNCT02595528Written as AGN-199201 ophthalmic solution
- Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and LaryngoscopyCompletedPhase 4Lumbini Medical CollegeNCT03620513Written as Decongestant (oxymetazoline 0.05%)
- TransMEM Gas Exchange -- Project 1, Aim 2CompletedPhase 1Cuneyt M. AlperNCT01925729Written as Oxymetazoline
- AGN-199201 for the Treatment of Erythema With RosaceaCompletedPhase 2AllerganNCT01735201Written as AGN-199201 Dose A
See all 45 studies that test Oxymetazoline →
Given in every arm · 3 — Oxymetazoline is usual care beside what is tested
- Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride (HCL) 1% Cream for Erythematotelangiectatic RosaceaCompletedPhase 4Candela CorporationNCT04153188Written as Oxymetazoline HCL 1% Cream
- A Study of Nasal Glucagon in Participants With a Common ColdCompletedPhase 1Eli Lilly and CompanyNCT02778100Written as Oxymetazoline
- NoAL (HPMC) in Combination With Oxymetazoline in Patients With Allergic RhinitisCompletedPhase 2Association Asthma, BulgariaNCT01986582Written as Oxymetazoline
As the comparator · 1 — what is tested is compared with Oxymetazoline
Codes
What other systems call Oxymetazoline · ClinicalTrials.gg INT007941
- MeSH (NLM) D010109OxymetazolineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 8VLN5B44ZYOXYMETAZOLINEConfirmed FDA, NLM, Wikidata
- RxNorm 7812Confirmed FDA, Wikidata
- Wikidata Q417813oxymetazolineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61871OxymetazolineOne source FDA
- DrugBank DB00935One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D010109 | Oxymetazoline | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 8VLN5B44ZY | OXYMETAZOLINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7812 | — | Confirmed FDA, Wikidata |
| Wikidata | Q417813 | oxymetazoline | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61871 | Oxymetazoline | One source FDA |
| DrugBank | DB00935 | — | One source Wikidata |
Also registered as oxymetazoline hydrochloride (UNII K89MJ0S5VY · RxNorm 106101).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.