Drug
Tapentadol clinical trials
Also written Nucynta, Palexia and CG5503 IR.
- studies test it
- 60
- open now
- 1
- in phase 3
- 34
- first study started
- 2003
Keep track of what changes. Save the Tapentadol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Combined with it in one product
Studies by the year they started
59 studies that test it; most in 2007 (10)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 4 |
| 2007 | 10 |
| 2008 | 5 |
| 2009 | 6 |
| 2010 | 7 |
| 2011 | 7 |
| 2012 | 3 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 4 |
| 2017 | 2 |
| 2018 | 1 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 6
- Phase 2
- 10
- Phase 3
- 34
- Phase 4
- 9
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 49 · Other 11
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (20) · Grünenthal GmbH (18) · Janssen Research & Development, LLC (3) · Ortho-McNeil Janssen Scientific Affairs, LLC (3) · Janssen Pharmaceutical K.K. (3) · All India Institute of Medical Sciences, Bhubaneswar (2) · ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" (1) · Shaukat Khanum Memorial Cancer Hospital & Research Centre (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses Tapentadol is read from its arms, and is right about nine times in ten.
Testing it · 60
- Tapentadol vs Tramadol in Total Knee ArthroplastyRecruitingPhase 4University of ThessalyNCT06269770Written as Tapentadol
- Tapentadol vs Pregabalin for Postoperative Pain in Lower Limb SurgeryCompletedNot applicableISSSTE Hospital Regional "Gral. Ignacio Zaragoza"NCT07587645Written as Tapentadol
- Role of Preoperative Tapentadol in Reduction of Perioperative Analgesic Requirement After Breast Conservative Surgery in Cancer Patients.CompletedNot applicableShaukat Khanum Memorial Cancer Hospital & Research CentreNCT07320781Written as Tapentadol
- Tapentadol Versus Oxycodone - a Mechanism-based Treatment Approach in Neuropathic PainTerminatedPhase 4University Hospital Schleswig-HolsteinNCT01458015Written as tapentadol, oxycodone
- Comparison of Postoperative Analgesia Between Intravenous Paracetamol and Intranasal TapentadolCompletedPhase 4Kempegowda Institute of Medical Sciences, BangaloreNCT05999890Written as Tapentadol Hydrochloride
- Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs PlaceboCompletedPhase 3St. Olavs HospitalNCT02604446Written as Tapentadol
- Safety and Efficacy of Pre-emptive Tapentadol vs Pregabalin in Post Operative Pain Following SurgeryCompletedPhase 4All India Institute of Medical Sciences, BhubaneswarNCT03604354Written as Tapentadol 100 MG Oral Tablet
- A Study to Look at Tapentadol Oral Solution in Children and Adolescents in PainCompletedPhase 3Grünenthal GmbHNCT02081391Written as Tapentadol oral solution 4 mg/mL
- A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and MorphineCompletedPhase 3Grünenthal GmbHNCT00472303Written as Tapentadol Extended Release
- Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative PainCompletedPhase 2Grünenthal GmbHNCT01729728Written as Tapentadol
- Tapentadol in Chronic Malignant Tumour Related PainTerminatedPhase 3Grünenthal GmbHNCT01264887Written as Tapentadol Prolonged Release
- A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and MorphineTerminatedPhase 3Grünenthal GmbHNCT00505414Written as Tapentadol in the Titration Phase
- Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and PregabalinCompletedPhase 4Grünenthal GmbHNCT01352741Written as Tapentadol Prolonged Release
- A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal HysterectomyCompletedPhase 3Grünenthal GmbHNCT00478023Written as CG5503 IR
- Intravenous Tapentadol in Post-Bunionectomy PainCompletedPhase 2Grünenthal GmbHNCT01435577Written as Tapentadol
- Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular AnalgesicCompletedPhase 3Grünenthal GmbHNCT00983073Written as Tapentadol
- A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the KneeCompletedPhase 3Grünenthal GmbHNCT00486811Written as Tapentadol ER (100 to 250 mg twice daily)
- Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.TerminatedPhase 3Grünenthal GmbHNCT00982280Written as Tapentadol PR
- A Study to Look at Tapentadol Tablets in Children and Adolescents in PainCompletedPhase 2/3Grünenthal GmbHNCT02151682Written as Tapentadol prolonged release
- Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and WomenCompletedPhase 1Grünenthal GmbHNCT03951402Written as 100 mg CG5503 (tapentadol hydrochloride) PR tablet
See all 60 studies that test Tapentadol →
Given in every arm · 2 — Tapentadol is usual care beside what is tested
- Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)CompletedPhase 1Grünenthal GmbHNCT03979989Written as Tapentadol IR capsule
- Investigation How CG5503 is Taken up and Excreted From the Body After 2 Minutes Intravenous Infusion With and Without Oral Co-administration of CharcoalCompletedPhase 1Grünenthal GmbHNCT03951987Written as 4 ml CG5503
As the comparator · 1 — what is tested is compared with Tapentadol
Codes
What other systems call Tapentadol · ClinicalTrials.gg INT006725
- MeSH (NLM) D000077432TapentadolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) H8A007M585TAPENTADOLConfirmed FDA, NLM, Wikidata
- RxNorm 787390Confirmed FDA, Wikidata
- Wikidata Q414463tapentadolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C72139TapentadolOne source FDA
- DrugBank DB06204One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077432 | Tapentadol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | H8A007M585 | TAPENTADOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 787390 | — | Confirmed FDA, Wikidata |
| Wikidata | Q414463 | tapentadol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C72139 | Tapentadol | One source FDA |
| DrugBank | DB06204 | — | One source Wikidata |
Also registered as tapentadol hydrochloride (UNII 71204KII53 · RxNorm 857492).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.