Arthralgia clinical trials
The registry lists 277 studies for Arthralgia across more than 10 countries. 54 are recruiting or about to start. 128 of them are mainly about Arthralgia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Shoulder Pain too: 1,008 studies, 220 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (8) · Investigación en Hemofilia y Fisioterapia (8) · SI-BONE, Inc. (5) · Novartis Pharmaceuticals (5) · ESM Technologies, LLC (5) · Vedic Lifesciences Pvt. Ltd. (4) · University of Michigan Rogel Cancer Center (4) · Cairo University (3)
What is being tested here
Drugs under test in Arthralgia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Hydroxychloroquine | 2 | 0 | 3 |
| Hyaluronic Acid | 1 | 0 | 2 |
| Arumakimig | 1 | 0 | 1 |
| Prunus cerasus whole | 1 | 0 | 1 |
| Creatine monohydrate | 1 | 0 | 1 |
| Creatine | 1 | 0 | 1 |
| Dapansutrile | 1 | 1 | 1 |
| Hydrocortisone | 1 | 1 | 1 |
| Glucose | 1 | 0 | 1 |
| Tapentadol | 0 | 6 | 6 |
Drug classes tested here Opioids 8 · NSAIDs 5 · COX-2 inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Web-based Pain Coping Skills Training for Breast Cancer Survivors With AI-Associated Arthralgia · Phase 3 · Northwestern University
- Dec 2026Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare · Phase 3 · Olatec Therapeutics, Inc.
- Apr 2027The MUSE Study for Menopausal Arthralgia · Phase 3 · National University Hospital, Singapore
- Nov 2026Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain. · Fundación Universidad Católica de Valencia San Vicente Mártir
- Dec 2026Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty · Luzerner Kantonsspital
- Jan 2027Psorcast Mobile Study · Sage Bionetworks
- Feb 2027Effect of Agar/Collagen-based Compounds on Osteoarticular Pain: Randomized Triple-blind Clinical Trial · Fundació Eurecat
- Mar 2027AKU Study - Acupuncture for Aromatase Inhibitor-Induced Musculoskeletal Syndrome · Masaryk Memorial Cancer Institute
- Apr 2027Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation · Stanford University
- Jun 2027The Effect of LDL557 on Improving Degenerative Arthritis in the Elderly · Chung Shan Medical University
Who these studies take
Of the 35 Arthralgia studies recruiting now, 18 (51%) set no upper age limit and 16 (46%) stop at 75 or younger. 1 (3%) take children under 18. 8 (23%) are for women only and 2 (6%) for men only; 9 (26%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 19 (54%) | 18 (51%) |
| 30 | 25 (71%) | 22 (63%) |
| 40 | 31 (89%) | 26 (74%) |
| 50 | 32 (91%) | 26 (74%) |
| 65 | 30 (86%) | 25 (71%) |
| 75 | 22 (63%) | 19 (54%) |
| 85 | 19 (54%) | 17 (49%) |
Across all 277 studies, recruiting or not: 35% stop at 75 or younger and 24% at 65; 6% take children; 22% are for women only and 5% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Arthralgia studies take
Of 82 interventional studies with no phase under Arthralgia, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo4–29 · 82 studies | — | 15 mo4–31 · 64 studies |
| Observational | 22 mo7–56 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting3
- Pilot Study of Hydroxychloroquine for the Treatment of AIMSSNov 10, 2026NCT07825454
- Undenatured Type II Collagen for Knee Osteoarthritis PainOct 22, 2026NCT07870967
- Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.Oct 15, 2026NCT05780450
Newly registered3
- AKU Study - Acupuncture for Aromatase Inhibitor-Induced Musculoskeletal SyndromeNov 2, 2026NCT07909785
- Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal DisordersOct 29, 2026NCT07903142
- Undenatured Type II Collagen for Knee Osteoarthritis PainOct 13, 2026NCT07870967
Studies
Recruiting first, then most recently updated. Showing 50 of 277. Browse all 277 → or search them.
- Pilot Study of Hydroxychloroquine for the Treatment of AIMSSRecruitingNCT07825454Phase 21 country
- A 52-Week Study Evaluating the Efficacy and Safety of Arumakimig (MAS825) in Participants With VEXAS Followed by Open-Label Extension (OLE) PeriodRecruitingNCT07748624Phase 21 country
- Evaluation of the Efficacy and Acceptability of a Phytotherapy Combining Devil's Claw, Blackcurrant and Meadowsweet for the Management of Aromatase Inhibitor-induced Arthralgia in Patients Treated for Localized Breast Cancer in the Adjuvant SettingNot yet recruitingNCT07859319Phase 41 country
- Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal DisordersNot yet recruitingNCT07903142Not applicable1 country
- Immune-Mediated Pathophysiology And Clinical Triage ProgramRecruitingNCT04354649Phase 21 country
- Undenatured Type II Collagen for Knee Osteoarthritis PainRecruitingNCT07870967Not applicable1 country
- Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.RecruitingNCT05780450Not applicable1 country
- Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint PainRecruitingNCT06081101Early Phase 11 country
- LINQ® Procedure vs. Conventional Medical Management for Sacroiliac DysfunctionRecruitingNCT07558278Phase 41 country
- Anti-inflammatory Effects of Curcumin, Ginger and Piperine Supplementation in Ultra-trail Runners: a Double-blind Randomized Placebo-controlled TrialRecruitingNCT07699575Not applicable1 country
- Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer SurvivorsRecruitingNCT06728579Phase 21 country
- Comparison Between Traditional Bipolar Radiofrequency and Cooled Radiofrequency in Sacroiliac Joint Pain PatientsNot yet recruitingNCT07749599Not applicable1 country
- Electroacupuncture vs. Auricular Acupressure vs. Waitlist Control for Breast Cancer Endocrine Therapy-Related Joint PainRecruitingNCT07490938Not applicable1 country
- Effects of Maine Oils on Joint Stiffness and PainNot yet recruitingNCT07786181Not applicable
- The Effect of LDL557 on Improving Degenerative Arthritis in the ElderlyEnrolling by invitationNCT06658821Not applicable1 country
- Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense ExerciseRecruitingNCT07766720Not applicable1 country
- Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal SymptomsRecruitingNCT06123286Early Phase 11 country
- Dietary Supplements and Middle Aged Women (Collagen & Omega)RecruitingNCT07740967Not applicable1 country
- Biologic Augmentation of TMJ Arthroscopy Using BMACRecruitingNCT07536399Phase 31 country
- Dietary Supplements and Middle Aged Women (Creatine)RecruitingNCT07729930Not applicable1 country
- Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated PainNot yet recruitingNCT07692737Not applicable
- Posterior-Inferior Intra-articular Cortical Piercing Titanium Implant for Sacroiliac Joint Fusion: Evaluation of Safety and Effectiveness OutcomesNot yet recruitingNCT07565545
- Post-Market Clinical Study Using TRAQ™ for Minimally Invasive Posterior Sacroiliac Joint FusionRecruitingNCT075472151 country
- Additional Effects of Mulligan Mobilization With Movement Along With Core Strengthening Exercises in Postpartum Females With Sacroiliac Joint DysfunctionRecruitingNCT07526038Not applicable1 country
- Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body PainRecruitingNCT07325513Not applicable1 country
- PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial)Not yet recruitingNCT07498660Not applicable1 country
- Study of Dapansutrile Tablets in Subjects With an Acute Gout FlareRecruitingNCT05658575Phase 2/35 countries
- Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal SymptomsNot yet recruitingNCT07409948Not applicable
- Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip PainRecruitingNCT03711773Not applicable1 country
- CMCT Versus CSE in Treatment of SIJ PainNot yet recruitingNCT07370272Not applicable1 country
- Effect of Agar/Collagen-based Compounds on Osteoarticular Pain: Randomized Triple-blind Clinical TrialRecruitingNCT07318896Not applicable1 country
- Impact OF Cooled Versus Thermal Radiofrequency Denervation In Management Of Chronic Lumber Facet Joint PainRecruitingNCT07309731Not applicable1 country
- JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal WomenRecruitingNCT07238478Not applicable1 country
- Dietary Wild Blueberries and Joint HealthRecruitingNCT06828159Not applicable1 country
- Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural PopulationsRecruitingNCT07179016Not applicable1 country
- Predictors of Physical Activity in Adult Patients With Hemophilic ArthropathyNot yet recruitingNCT069604991 country
- Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee OsteoarthritisNot yet recruitingNCT06864390Not applicable
- Manual Therapy in Hemophilic Arthropathy of the AnkleRecruitingNCT06816056Not applicable1 country
- Combined Corticosteroid Injections and Shockwave Therapy for Sacroiliac Joint PainNot yet recruitingNCT06761768Not applicable
- Effect of a Specific Hand Intervention in Women With Arthralgia Secondary to Hormone Therapy Following Breast Cancer.Not yet recruitingNCT06746376Not applicable1 country
- Topical Treatment for TMJ ArthralgiaRecruitingNCT05816226Phase 31 country
- The MUSE Study for Menopausal ArthralgiaRecruitingNCT06530459Phase 2/31 country
- Trends in Prevalence of 11 Site-specific Musculoskeletal Pain Among U.S. Adults, 1999-2018Enrolling by invitationNCT06494670
- Prevalence of Muscle and Nerve and Joint PainRecruitingNCT064024481 country
- Subsartorial Nerve Block and Femoral Nerve Block in Total Knee ArthroplastyRecruitingNCT06074744Not applicable1 country
- Dextrose Prolotherapy on Articular CartilageRecruitingNCT06301958Not applicable1 country
- Efficacy of Hyaluronic Acid Injection in Knee OsteoarthritisRecruitingNCT06279507Phase 41 country
- Effectiveness of Cucumber Extract on Joint PainNot yet recruitingNCT06246383Not applicable
- Finding the Optimal Aim of Correction in Opening Wedge High Tibial OsteotomyNot yet recruitingNCT06134050Not applicable
- Shock Wave and Core Exercises for Postpartum Sacroiliac PainNot yet recruitingNCT06124365Not applicable