ClinicalTrials.gg
RecruitingNCT06883669Updated Apr 4, 2025

The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound

An observational study in Education and Joint Diseases, sponsored by West China Hospital. Recruiting at 1 site in China. Open to participants aged 18 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-04.

Sponsored by West China Hospital · Observational

From the registry’s dates

  • Primary completion was expected by May 2025, 1 year 6 months ago, but the record still lists the study as recruiting.
  • Started Jan 2021; still recruiting 5 years 10 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
500
Ages
18 Years to 100 Years
Sex
All
01

Study summary

  1. To develop an AI system that can automatically identify standard sections and save images during wrist and hand joint ultrasound scans, while labeling key anatomical structures.
  2. To recruit sonographers untrained in musculoskeletal ultrasound, train them in wrist and hand joint scans, and compare their scanning speed and image quality when using and not using the AI system.
Read the detailed description

Research Background Musculoskeletal ultrasound, a rapidly evolving technique for ultrasound - based diagnosis and treatment of the musculoskeletal system, has seen expanding applications in visualizing peripheral nerves, muscles, tendons, joints, and skin thanks to improved ultrasound resolution. It offers advantages like convenience, cost - effectiveness, safety, real - time dynamics, continuous follow - up, and fast reporting. Given the high incidence and wide prevalence of rheumatic and immunological diseases, high - frequency ultrasound is gaining clinical attention. Consequently, learning and promoting musculoskeletal ultrasound is clinically valuable and necessary. However, this field faces challenges such as operator dependence, slow skill improvement and subjective differences in ultrasound diagnosis criteria and assessment methods for rheumatic diseases. The emergence of intelligent tools (AI) can address the urgent need for fast, accurate, and standardized ultrasound diagnosis. While AI has been used in multiple ultrasound sub - specialties, its application in musculoskeletal ultrasound is limited. This study aims to develop an AI - assisted musculoskeletal ultrasound examination system. It will help ultrasonographers by real - time segmenting structures like muscles, tendons, bone cortex, peripheral nerves, joint spaces, and blood vessels, extracting lesions (e.g., synovitis, tenosynovitis, bone erosion, cartilage destruction), and assessing lesion severity, thereby improving diagnostic accuracy and efficiency. Additionally, the system will shorten the learning cycle, enhance learning efficiency for musculoskeletal ultrasound, and accelerate its adoption in hospitals at all levels.

Research Objectives Primary Objective: To develop a musculoskeletal ultrasound AI - assisted examination system. This system will identify standard examination sections and continuous dynamic images of wrist and hand joints, mark specific structures in real - time, extract lesions, and assess their severity, enhancing examination efficiency and accuracy.

Secondary Objective: To help ultrasonographers shorten their learning period and master musculoskeletal ultrasound examination skills more quickly through the application of the AI - assisted system.

02

Conditions studied

  • Education
  • Joint Diseases

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Keywords

  • ultrasound
  • hand
  • medical education
  • artificial intelligence
  • deep learning
  • wrist
03

In context

Joint Diseases

386 studies on the registry are indexed under Joint Diseases; 64 are open to participants now.

This study's planned enrollment of 500 is above the median of 86 across 116 observational studies indexed under Joint Diseases.

Browse Joint Diseases studies →

Lead sponsor

West China Hospital is the lead sponsor of 501 studies on the registry; 246 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

healthy individuals and rheumatoid arthritis (RA) patients,sonographers untrained for MSK ultrasound

Eligibility criteria

(1) Research Subjects-for AI system establishment

Inclusion Criteria:

  1. Healthy volunteers with good compliance
  2. No history of disease on peripheral nerve, muscle, or tendons;
  3. No early - stage RA or history of RA.

Exclusion Criteria:

  1. Amputees or those with limb disabilities.

Individuals with poor compliance.

(2) Research Subjects-for AI system validation

Inclusion Criteria:

  1. Sonographers with at least 2 years of ultrasound scanning experience

Exclusion Criteria:

  1. Those who have performed musculoskeletal ultrasound scanning or received related training
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
500 participants (estimated)
Patient registry
No

Groups and cohorts

  • Research Subjects-for AI system establishment

    Collect ultrasound images of wrist and hand joints, annotate and segment them frame - by - frame for model training.

  • Research Subjects-for AI system validation

    Recruit sonographers untrained in musculoskeletal ultrasound, train them in wrist and hand joint scans, and compare their scanning speed and image quality when using and not using the AI system.

06

What researchers measure

Primary outcomes

  1. Image acquisition is complete

    Time frame: Day 1

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jan 2021 (actual). Primary completion is estimated for May 2025, 52 months after the start.

Of 58 observational studies under Joint Diseases, half reached primary completion within 62 months of starting (the median), counting those still running; a quarter within 28 and three quarters within 153. This study's planned 52 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 11, 2025
First posted
Mar 19, 2025
StartActual
Jan 1, 2021
Primary completionEst.
May 1, 2025
CompletionEst.
Jun 1, 2025
Last update
Apr 4, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06883669
Responsible party
Xinyi Tang (Principal Investigator, West China Hospital) — Principal investigator
First posted
Mar 19, 2025
Start date
Jan 1, 2021
Primary completion
May 1, 2025 (estimated)
Completion
Jun 1, 2025 (estimated)
Last update
Apr 4, 2025

Study contacts

Xinyi Tang
Contact
tangxinyi1996@outlook.com
+8615680819215
Xinyi Tang
principal investigator · Department of Medical Ultrasound, West China Hospital, Sichuan University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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