Hypoxia clinical trials
The registry lists 1,076 studies for Hypoxia across more than 10 countries. 213 are recruiting or about to start. 529 of them are mainly about Hypoxia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Hypoxia-Ischemia, Brain: 1,419 studies, 326 open.
ClinicalTrials.gov finds 2,025 studies for Hypoxia. How that becomes 1,076 here
This page counts the studies the registry files under Hypoxia, and those it files under no condition that list Hypoxiathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,025Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −343Filed under a narrower condition, counted on its own pageHypoxia-Ischemia, Brain 242 · Hypoxia, Brain 63 · Fetal Hypoxia 21
- −88List Hypoxia as a condition, but the registry did not file them under itMost often written as “Altitude Hypoxia” (18), “Hypoxia, Altitude” (14), and “Acute Respiratory Failure With Hypoxia” (11). The registry filed them under other conditions only, most often Altitude Sickness (36) and Respiratory Insufficiency (13).
- −533Match it another way314 name it in the title, 82 in a keyword, and 137 by a synonym or other text the search reads.
- 1,061Counted here and found by its search37 of them list Hypoxia in their own words; the registry filed them under no condition.
- +15
Counted here, but its search does not find them
- Building Respiratory Support in East Africa Through High Flow Versus Standard Flow Oxygen EvaluationNCT05754034
- Benefits of High Flow Nasal Cannula Oxygen for Preoxygenation During Intubation in Non Severely Hypoxemic PatientsNCT02700321
- Optiflow® to Prevent Post-Extubation Hypoxemia afteR Abdominal Surgery (the OPERA Trial)NCT01887015
- Bradycardia Recognition and Detection in Young Infants Part-INCT05774470
- Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal EndoscopyNCT07673042
- Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen SurgeryNCT07652385
- Postoperative SpO₂/FiO₂ Ratio and Analgesic Methods in Laparoscopic SurgeryNCT07401589
- Preoperative ROX Index for Predicting Early Postoperative Hypoxemia in ENT SurgeryNCT07344103
- Transoral Nasal Cannula Oxygen Therapy for Mouth-Breathing Patients in the Postanesthesia Care UnitNCT07841223
- Effect of Lateral Versus Supine Positions on Postoperative HypoxemiaNCT07545642
- Effect of Different Body Positions on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and ColonoscopyNCT07587970
- Lung Function Monitoring During Hypoxemia EpisodesNCT06535074
- High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound ProcedureNCT06637280
- The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained SwimmersNCT05095311
- Monitoring of Cerebral and Abdominal Tissue Oxygen Saturation in NeonatesNCT03149731
- 1,076The count on this page
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Status
Who runs them
University of Zurich (36) · RenJi Hospital (14) · Medtronic - MITG (13) · Zhejiang University (13) · University of Colorado, Denver (12) · Nihon Kohden (10) · University Hospital, Grenoble (10) · Silvia Ulrich Somaini (9)
What is being tested here
Drugs under test in Hypoxia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Remimazolam | 4 | 0 | 5 |
| Propofol | 2 | 0 | 3 |
| Acetazolamide | 1 | 1 | 11 |
| Doxapram | 1 | 1 | 2 |
| Ferric carboxymaltose | 1 | 0 | 2 |
| Alfentanil | 1 | 0 | 2 |
| Centhaquine | 1 | 0 | 1 |
| Fentanyl | 1 | 0 | 1 |
| Esketamine | 1 | 0 | 1 |
| Ferrous sulfate | 1 | 0 | 1 |
Drug classes tested here Opioids 2 open · Diuretics 1 open · Stimulants 1 open · Corticosteroids 1 open · Bronchodilators 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP · Kocaeli University
- Nov 2026Prevention of Desaturations Using Positive Airway Pressure or Capnometry During ERCP · Karl Landsteiner University of Health Sciences
- Dec 2026Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy · Second Affiliated Hospital of Wenzhou Medical University
- Dec 2026Lung Ultrasound Score and Postoperative Pulmonary Complications in Major Non-Thoracic Surgery · Dicle University
- Dec 2026Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning. · Iconic Solutions By Murcia SL
- Dec 2026Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia · University of Missouri-Columbia
- Dec 2026The Effects of Endotracheal Suctioning on Pain and Serum Markers · Loma Linda University
- Dec 2026Remimazolam for Bronchoscopy in High-Risk Patients · First Affiliated Hospital of Zhejiang University
- Dec 2026Hypoxia Pathways for Early Recovery After Spinal Cord Injury · University of Florida
- Dec 2026Effects of Normobaric Hypoxia Exercise Program on Bone Turnover Markers and Metabolism in Premenopausal Women · University School of Physical Education, Krakow, Poland
Who these studies take
Of the 125 Hypoxia studies recruiting now, 53 (42%) set no upper age limit and 45 (36%) stop at 75 or younger. 15 (12%) take children under 18. 5 (4%) are for women only and 2 (2%) for men only; 33 (26%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (6%) | 7 (6%) |
| 18 | 103 (82%) | 102 (82%) |
| 30 | 107 (86%) | 105 (84%) |
| 40 | 108 (86%) | 106 (85%) |
| 50 | 104 (83%) | 101 (81%) |
| 65 | 100 (80%) | 99 (79%) |
| 75 | 85 (68%) | 84 (67%) |
| 85 | 68 (54%) | 69 (55%) |
Across all 1,076 studies, recruiting or not: 43% stop at 75 or younger and 35% at 65; 15% take children; 4% are for women only and 6% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypoxia studies take
Of 21 phase 1 interventional studies under Hypoxia, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 27 mo7–55 · 21 studies | — | — |
| Phase 1/2 | 16 mo6–32 · 13 studies | — | — |
| Phase 2 | 27 mo7–42 · 20 studies | — | — |
| Phase 4 | 19 mo13–47 · 17 studies | — | — |
| Interventional, no phase | 12 mo3–27 · 351 studies | 1 mo0–6 · 30 studies | 12 mo4–27 · 321 studies |
| Observational | 14 mo3–46 · 155 studies | 0 mo0–2 · 30 studies | 19 mo7–74 · 125 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Methodological Study of Exercise and Hypoxic Conditions in Healthy SubjectsOct 23, 2026NCT07671638
Results posted1
- Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration InterventionOct 14, 2026NCT06374225
Stopped1
- Automated Oxygen Titration With the EMILY.AI Device in a Respiratory Intermediate Care UnitSuspendedNov 2, 2026NCT06952816
Newly registered4
- HFNC vs Conventional Oxygen During Gastrocolonoscopy in Elderly PatientsNov 4, 2026NCT07916298
- Characterizing Tumor Hypoxia With BOLD-MRI to Predict Y-90 Treatment ResponseNov 4, 2026NCT07916376
- Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCTOct 29, 2026NCT07904234
- Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude RegionsOct 29, 2026NCT07904260
Studies
Recruiting first, then most recently updated. Showing 50 of 1,076. Browse all 1,076 → or search them.
- Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCTNot yet recruitingNCT07904234Not applicable1 country
- Extubation Safety Via Microstream EtCO₂ (IPI) MonitoringEnrolling by invitationNCT06975553Not applicable1 country
- Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 StudyRecruitingNCT061024993 countries
- ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their CaregiversNot yet recruitingNCT07778004Not applicable1 country
- HFNC vs Conventional Oxygen During Gastrocolonoscopy in Elderly PatientsNot yet recruitingNCT07916298Not applicable1 country
- The Role of Ultrasonographic Tracheal Measurements in Predicting Hypoxemia During Endobronchial Ultrasound-Guided Transbronchial Needle AspirationNot yet recruitingNCT075877361 country
- Characterizing Tumor Hypoxia With BOLD-MRI to Predict Y-90 Treatment ResponseNot yet recruitingNCT07916376Not applicable1 country
- Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude RegionsNot yet recruitingNCT07904260Not applicable1 country
- Influence of Intermittent Hypoxia on Loop Gain in Healthy SubjectsRecruitingNCT07409649Not applicable1 country
- Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary HypertensionRecruitingNCT055952001 country
- Ventilator Pressure and Optimization of Compliance and HemodynamicsRecruitingNCT06512935Not applicable1 country
- Methodological Study of Exercise and Hypoxic Conditions in Healthy SubjectsRecruitingNCT07671638Not applicable1 country
- Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain InjuriesAvailableNCT033274671 country
- LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT05798923Phase 21 country
- Pulse Oximeter Accuracy in Healthy Humans During HypoxiaRecruitingNCT061420191 country
- BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic SurgeryRecruitingNCT07851740Not applicable1 country
- Transoral Nasal Cannula Oxygen Therapy for Mouth-Breathing Patients in the Postanesthesia Care UnitRecruitingNCT07841223Not applicable1 country
- Developing New Ways to Detect Respiratory Impairment Early in ALSRecruitingNCT078445901 country
- Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)RecruitingNCT065752701 country
- Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under SedationNot yet recruitingNCT07637721Not applicable1 country
- Brain Connectivity and Corticospinal Excitability in Response to Moderate HypoxiaRecruitingNCT07516028Not applicable1 country
- Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative HypoxemiaNot yet recruitingNCT07827131Not applicable
- Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDSNot yet recruitingNCT05241067Phase 2
- Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.RecruitingNCT07432191Not applicable1 country
- Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?RecruitingNCT05467215Early Phase 11 country
- Impact of Early Aging and Menopause on the Vascular Responses to HypoxiaRecruitingNCT06417177Early Phase 11 country
- Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional HypoxemiaEnrolling by invitationNCT07512687Not applicable1 country
- Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAHNot yet recruitingNCT07804693Not applicable1 country
- Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals HNot yet recruitingNCT07804485Not applicable1 country
- Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy IndividualsNot yet recruitingNCT07804589Not applicable1 country
- Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAHNot yet recruitingNCT07804524Not applicable1 country
- Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAHNot yet recruitingNCT07804472Not applicable1 country
- Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAHNot yet recruitingNCT07801963Not applicable1 country
- Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Healthy Individuals HNot yet recruitingNCT07801872Not applicable1 country
- Evaluation of Neonatal Acute Hypoxia at Delivery Using Fetal Physiology and Eucapnic pH AssessmentNot yet recruitingNCT076292711 country
- Evaluation of the Melanin-Adjusted Blood Oxygen Sensor (MABOS) in ICU SettingsRecruitingNCT07799454Not applicable1 country
- Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy IndividualsNot yet recruitingNCT07797088Not applicable1 country
- Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAHNot yet recruitingNCT07797166Not applicable1 country
- Heated Humidified Oxygen in PACU PatientsNot yet recruitingNCT07778420Not applicable1 country
- Evaluation of the FreeO2 System for Oxygen Weaning After Acute Hypoxemic Respiratory FailureNot yet recruitingNCT07794124Not applicable
- Reminder-enhanced Incentive Spirometry EvaluationNot yet recruitingNCT07728214Not applicable
- High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary DiseaseNot yet recruitingNCT07791979Not applicable1 country
- Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With HypoxemiaRecruitingNCT07037836Phase 21 country
- DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)RecruitingNCT063884212 countries
- Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap ReconstructionsNot yet recruitingNCT07786610
- Dose-Escalation Study of Artesunate Patients With IPFRecruitingNCT05988463Phase 11 country
- Levetiracetam Extended-Release Plus Stupp Protocol for Hypoxic IDH-Wildtype GlioblastomaNot yet recruitingNCT07758062Phase 21 country
- A Prospective Cohort Study on Endoscopic Features of Upper Gastrointestinal Tract at High Altitude (Zaduo County)RecruitingNCT077553841 country
- Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric GastroscopyNot yet recruitingNCT07748884Phase 41 country
- Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized TreatmentRecruitingNCT061080891 country