Hypoxia, Brain clinical trials
The registry lists 81 studies for Hypoxia, Brain across more than 10 countries. 19 are recruiting or about to start. 35 of them are mainly about Hypoxia, Brain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Hypoxia-Ischemia, Brain too: 332 studies, 110 open.
Get an email when these change. Save the Hypoxia, Brain studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Assistance Publique - Hôpitaux de Paris (3) · University Hospital, Grenoble (3) · NICHD Neonatal Research Network (3) · University of Calgary (2) · Case Western Reserve University (2) · Region Skane (2) · Alexandria University (2) · Casa Colina Hospital and Centers for Healthcare (1)
What is being tested here
Drugs under test in Hypoxia, Brain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Emoxypine succinate | 0 | 1 | 1 |
| Lorazepam | 0 | 0 | 1 |
| Oxygen | 0 | 0 | 1 |
| Resveratrol | 0 | 0 | 1 |
| Phenobarbital | 0 | 0 | 1 |
| Levetiracetam | 0 | 0 | 1 |
| Lacosamide | 0 | 0 | 1 |
| Valproic Acid | 0 | 0 | 1 |
| Fosphenytoin | 0 | 0 | 1 |
| Baclofen | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Aquatic Therapy for Children With Neuromotor Deficits · Ohio State University
- Dec 2026Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory. · Direction Centrale du Service de Santé des Armées
- Jan 2027Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation · Region Skane
- Jan 2027Stepcare Extended Follow-up Substudy · Region Skane
- Feb 2027Cerebral Oximetry in Management of Post Cardiac Arrest · University of Calgary
- Nov 2027Brain Oxygen Optimization in Severe TBI, Phase 3 · University of Michigan
Who these studies take
Of the 13 Hypoxia, Brain studies recruiting now, 8 (62%) set no upper age limit and 2 (15%) stop at 75 or younger. 3 (23%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (23%) | 3 (23%) |
| 18 | 11 (85%) | 11 (85%) |
| 30 | 11 (85%) | 11 (85%) |
| 40 | 11 (85%) | 11 (85%) |
| 50 | 10 (77%) | 10 (77%) |
| 65 | 11 (85%) | 11 (85%) |
| 75 | 11 (85%) | 11 (85%) |
| 85 | 8 (62%) | 8 (62%) |
Across all 81 studies, recruiting or not: 48% stop at 75 or younger and 43% at 65; 37% take children; 4% are for women only and 2% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypoxia, Brain studies take
Of 33 interventional studies with no phase under Hypoxia, Brain, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo7–44 · 33 studies | — | 20 mo7–44 · 33 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 81. Browse all 81 → or search them.
- Thrombo-inflammation Biomarkers Trial in Acute Cerebral HypoxiaRecruitingNCT049715641 country
- Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain InjuryRecruitingNCT077822161 country
- Cool Prime Comparative Effectiveness Study for Mild HIERecruitingNCT046212791 country
- Portable MRI for Pediatric Hypoxic Ischemic Brain InjuryRecruitingNCT07577336Not applicable1 country
- Cerebral Oximetry in Management of Post Cardiac ArrestRecruitingNCT07829887Not applicable1 country
- Brain Radiotherapy Imaging for High-grade Glioma Using Hypoxia Targeting Through Oxygen-Enhanced ResponseNot yet recruitingNCT07670455Not applicable
- Promoting Recovery After Brain Injury Using Focused UltrasoundRecruitingNCT07277309Not applicable1 country
- Regulating Emotions and Behaviors After Brain InjuryRecruitingNCT05393492Not applicable1 country
- Ultrasound Stimulation for Patients in a Disorder of ConsciousnessRecruitingNCT06939348Not applicable1 country
- Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.Not yet recruitingNCT07585227Not applicable1 country
- Effect of Hypoxic Conditioning on Cerebrovascular Health in the ElderlyRecruitingNCT05048680Not applicable1 country
- Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent HypoxiaRecruitingNCT03255408Phase 1/21 country
- Endothelial Glycocalyx Damage in Brain Death Organ DonorsRecruitingNCT056091231 country
- Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)Enrolling by invitationNCT072641661 country
- Early Detection of Brain Injury After Congenital Heart Surgery in InfantsEnrolling by invitationNCT074249761 country
- The Effect of Respiratory Challenge on the BOLD SignalEnrolling by invitationNCT04258774Not applicable1 country
- Stepcare Extended Follow-up SubstudyRecruitingNCT06207942Not applicable10 countries
- Neuromuscular Fatigue During Exercise in COPD-HF OverlapRecruitingNCT05235685Not applicable1 country
- Brain Oxygenation in Newborns Due to Neuroaksial MethodsNot yet recruitingNCT06316596Not applicable
- NEO-REEDUC - Mixed Reality for Motor Rehabilitation: a Prospective, Multicenter, Controlled, Randomized, Open Study.CompletedNCT07063810Not applicable1 country
- Aquatic Therapy for Children With Neuromotor DeficitsActive, not recruitingNCT05753345Not applicable1 country
- Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)TerminatedNCT01192776Not applicable1 country
- Sedation, Temperature and Pressure After Cardiac Arrest and ResuscitationActive, not recruitingNCT05564754Not applicable15 countries
- Brain Oxygen Optimization in Severe TBI, Phase 3Active, not recruitingNCT03754114Not applicable2 countries
- The Efficacy of Wet Cupping Therapy on Cerebral OxygenationCompletedNCT06540781Not applicable1 country
- Cerebral Responses During Exercise in HypoxiaCompletedNCT01614119Not applicable1 country
- Antiseizure Medication in Seizure Networks at Early Acute Brain InjuryTerminatedNCT06081283Phase 41 country
- Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral IschemiaCompletedNCT06834490Phase 32 countries
- Uncovering the Acute Neurobiological Significance of Emerging Sexual BehaviorsCompletedNCT06602362Not applicable1 country
- ESWT for Shoulder Pain in Patients With Brain DamageCompletedNCT04320108Not applicable1 country
- Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in PediatricCompletedNCT06320743Not applicable1 country
- Preemie Hypothermia for Neonatal EncephalopathyCompletedNCT01793129Not applicable1 country
- Brain Network Disruptions Related to Traumatic ComaCompletedNCT03482115Not applicable1 country
- Neonatal Brain Oxygenation StudyActive, not recruitingNCT04439968Not applicable1 country
- Brain Oxygenation-IIActive, not recruitingNCT05171881Phase 21 country
- Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.CompletedNCT06306950Not applicable1 country
- Excitatory Prefrontal Weak Current Stimulation in Vegetative PatientsCompletedNCT04614792Not applicable1 country
- Early DiaGnosis of Anoxic Brain Injury for Resuscitated PatientsSuspendedNCT038066601 country
- Observational Study in Preterm Infants With Intracranial HemorrhageCompletedNCT016202031 country
- Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson's DiseaseCompletedNCT05214287Phase 1/21 country
- Passive Cooling Versus Blanket-Roll III on The Myocardial Function of Asphyxiated NeonatesCompletedNCT05652738Not applicable1 country
- The Use of LIFUP in Chronic Disorders of ConsciousnessCompletedNCT04921683Not applicable1 country
- Early Neurological Outcome in Newborns With Mild Encephalopathy:a Regional NetworkActive, not recruitingNCT057854811 country
- The Effect of Hypoxic and Normoxic Cerebral Oximetry Levels on Cognitive Functions After Carotid EndarterectomyCompletedNCT056524261 country
- Measuring Brain Activity of School Age ChildrenCompletedNCT034077291 country
- Analysis of Selective Cerebrovascular Distribution With FDCT in the AngiosuiteCompletedNCT03916133Not applicable1 country
- TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary ResuscitationCompletedNCT02056236Not applicable2 countries
- Feasibility of a Music Therapy Intervention to Decrease Stress During Pediatric Critical CareCompletedNCT04280744Not applicable1 country
- PREMOD2 With Near Infrared Spectroscopy Sub-studyStatus unknownNCT03145142Not applicable4 countries
- Tracheal Dilatation in Pediatric Patients With Acquired Tracheal Stenosis, and the Effects of Apneic OxygenationStatus unknownNCT05028023Not applicable1 country