Hemorrhoids clinical trials
The registry lists 238 studies for Hemorrhoids across more than 10 countries. 73 are recruiting or about to start. 214 of them are mainly about Hemorrhoids (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Fondation Hôpital Saint-Joseph (7) · The Affiliated Hospital of Putian University (5) · Societa Italiana di Chirurgia ColoRettale (5) · Universidade do Porto (4) · Medtronic - MITG (3) · Mansoura University (3) · Servier Russia (3) · Center of Endourology "Endocenter" (3)
What is being tested here
Drugs under test in Hemorrhoids studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lidocaine | 2 | 2 | 6 |
| Ketamine | 1 | 0 | 3 |
| Nifedipine | 1 | 0 | 1 |
| Mesoglycan | 1 | 0 | 1 |
| Botulinum toxin type A | 1 | 0 | 1 |
| Nitroglycerin | 1 | 0 | 1 |
| Metronidazole | 0 | 2 | 4 |
| Bupivacaine | 0 | 2 | 4 |
| Diosmin | 0 | 1 | 2 |
| Dexmedetomidine | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils · Medtronic Endovascular
- Nov 2026Evaluation of the Effectiveness of Micronized Purified Flavonoid Fraction (MPFF) in Patients With Haemorrhoids Undergoing Minimally Invasive Surgical Interventions · Servier Russia
- Nov 2026HEMOVAR Study on Hemorrhoids and Varicose Veins · Aydin Adnan Menderes University
- Dec 2026Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids · Mayo Clinic
- Dec 2026Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids · University Hospitals of North Midlands NHS Trust
- Dec 2026Comparison of the Clinical Effects of Open, Closed, and Semi-close Hemorrhoidectomy. · The Affiliated Hospital of Putian University
- Dec 2026Trial of Latex vs Non-latex Hemorrhoid Banding · Huntington Memorial Hospital
- Dec 2026Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy · Sana'a University
- Dec 2026HEmorrhoidAl Disease in Inflammatory Bowel Disease: a Multicenter Prospective Cohort Study · Treviso Regional Hospital
- Dec 2026AI-Assisted Written Information in Symptomatic Hemorrhoidal Disease · Sanliurfa Education and Research Hospital
Who these studies take
Of the 38 Hemorrhoids studies recruiting now, 15 (39%) set no upper age limit and 11 (29%) stop at 75 or younger. 2 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (3%) | 1 (3%) |
| 18 | 34 (89%) | 34 (89%) |
| 30 | 38 (100%) | 38 (100%) |
| 40 | 38 (100%) | 38 (100%) |
| 50 | 37 (97%) | 37 (97%) |
| 65 | 36 (95%) | 36 (95%) |
| 75 | 32 (84%) | 32 (84%) |
| 85 | 22 (58%) | 22 (58%) |
Across all 238 studies, recruiting or not: 34% stop at 75 or younger and 14% at 65; 6% take children; 2% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hemorrhoids studies take
Of 70 interventional studies with no phase under Hemorrhoids, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 23 mo10–35 · 70 studies | — | 23 mo12–35 · 65 studies |
| Observational | 15 mo10–26 · 27 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
Newly registered3
- Auricular Indwelling Needles Added to Diosmin/Hesperidin for Grade I-II Internal Hemorrhoids With Heat-Toxin SyndromeOct 27, 2026NCT07899229
- Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy PainOct 22, 2026NCT07889869
- Ligasure Versus Conventional Diathermy in HemorrhoidectomyOct 16, 2026NCT07878546
Studies
Recruiting first, then most recently updated. Showing 50 of 238. Browse all 238 → or search them.
- Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)RecruitingNCT07179601Not applicable1 country
- Auricular Indwelling Needles Added to Diosmin/Hesperidin for Grade I-II Internal Hemorrhoids With Heat-Toxin SyndromeNot yet recruitingNCT07899229Not applicable
- Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy PainEnrolling by invitationNCT07889869Not applicable1 country
- Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization TreatmentNot yet recruitingNCT07264413
- Ligasure Versus Conventional Diathermy in HemorrhoidectomyRecruitingNCT07878546Not applicable1 country
- Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable CoilsEnrolling by invitationNCT076398531 country
- Evaluation of Polidocanol Foam Sclerotherapy in Symptomatic Internal Hemorrhoids: A Prospective StudyNot yet recruitingNCT07866248Phase 4
- Laser Hemorrhoidoplasty Versus Open Hemorrhoidectomy for Postoperative PainNot yet recruitingNCT07846904Not applicable
- Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal HemorrhoidsNot yet recruitingNCT07844629Phase 21 country
- Evaluation of the Effectiveness of Micronized Purified Flavonoid Fraction (MPFF) in Patients With Haemorrhoids Undergoing Minimally Invasive Surgical InterventionsRecruitingNCT076471721 country
- Trial of Latex vs Non-latex Hemorrhoid BandingRecruitingNCT06625138Not applicable1 country
- Sutureless Hemorrhoidectomy Versus Conventional Ligation in Advanced HemorrhoidsRecruitingNCT07824999Not applicable1 country
- Pudendal Nerve Block Techniques for Pain Control After HemorrhoidectomyNot yet recruitingNCT07813338Not applicable
- AI-Assisted Written Information in Symptomatic Hemorrhoidal DiseaseRecruitingNCT07701798Not applicable1 country
- Data-driven Clustering in Hemorrhoid Surgery: Retrospective Monocentric Study for the Identification of Clinical PhenotypesEnrolling by invitationNCT074279271 country
- Cryotherapy for Post-Hemorrhoidectomy PainNot yet recruitingNCT07714122Not applicable1 country
- Validation of HDSS and SHS-HD in Chinese Patients With HemorrhoidsNot yet recruitingNCT07713966
- Postoperative Pain and Tenesmus After Doppler-Guided Hemorrhoidal Artery Ligation With or Without MucopexyNot yet recruitingNCT07710053Not applicable
- Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidSRecruitingNCT07559630Not applicable1 country
- Oral Nifedipine Versus Placebo for Pain and Healing After HemorrhoidectomyNot yet recruitingNCT07659665Phase 41 country
- Nimsai Herbal for Grade 2-3 Hemorrhoids: A Quadruple-Blind Placebo-Controlled Mechanistic TrialNot yet recruitingNCT07669662Phase 31 country
- GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid ObesityNot yet recruitingNCT076687651 country
- Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal HemorrhoidsRecruitingNCT061062691 country
- Prospective HemorrhoIdaL EmboliSation (PILES) RegistryRecruitingNCT076357841 country
- Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding HemorrhoidsEnrolling by invitationNCT07161765Not applicable1 country
- SHAPE Versus Milligan-Morgan Hemorrhoidectomy for Hemorrhoidal DiseaseRecruitingNCT07598630Not applicable1 country
- HEMOVAR Study on Hemorrhoids and Varicose VeinsRecruitingNCT073174921 country
- Ketamine for Post-operative Analgesia in HemorrhoidectomyRecruitingNCT04248205Phase 41 country
- Low Excision and High Suspension Hemorrhoidectomy Versus Conventional Milligan-Morgan Hemorrhoidectomy for Grade III-IV Mixed HemorrhoidsNot yet recruitingNCT07495046Not applicable
- PUSHES (Pudendal Block Versus Sacral ESP Hemorrhoidectomy Study)RecruitingNCT07350460Not applicable1 country
- Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal DiseaseRecruitingNCT06170736Not applicable1 country
- Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative PainRecruitingNCT07399860Phase 21 country
- Comparison of the Clinical Effects of Open, Closed, and Semi-close Hemorrhoidectomy.Not yet recruitingNCT07196865Not applicable
- Hemorrhoid Suture Mucopexy Combined With Laser HemorrhoidoplastyRecruitingNCT074047741 country
- Application Effects of Wrist-Ankle Acupuncture in Patients With Different Types of Pain Following Perianal SurgeryRecruitingNCT07340307Not applicable1 country
- Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal DiseaseRecruitingNCT072958861 country
- Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal DiseaseRecruitingNCT05697562Not applicable1 country
- Acupuncture for Post-hemorrhoidectomy Pain ControlNot yet recruitingNCT07238504Not applicable
- Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in HemorrhoidectomyRecruitingNCT06969274Not applicable1 country
- Comparison of Clinical Effects Between Routine and High-frequency Follow-up After Hemorrhoids SurgeryNot yet recruitingNCT07183332Not applicable1 country
- Efficacy of Methylene Blue Plus Ropivacaine for Post-Hemorrhoidectomy Pain.Not yet recruitingNCT07164807Phase 41 country
- "Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")RecruitingNCT07159334Not applicable1 country
- Trans-radial Superior Rectal Artery Embolisation for HaemorrhoidsRecruitingNCT06175325Not applicable1 country
- Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With HemorrhoidsRecruitingNCT07128979Phase 41 country
- Effect of Red and Blue Light Irradiation on Wound Healing After Hemorrhoid SurgeryNot yet recruitingNCT07121686Not applicable1 country
- Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic SurgeryRecruitingNCT06798155Not applicable1 country
- ORal Aminaphtone and Combined LidocainERecruitingNCT070265131 country
- Evaluation of the Analgesic Efficacy of an Ultrasound-guided Transperineal Pudendal Block in Outpatient Hemorrhoidal SurgeryNot yet recruitingNCT07015775Not applicable1 country
- Cough and HemorrhoidsRecruitingNCT068782091 country
- Traditional Medicine Syndromes in Internal Hemorrhoids: a Cross-Sectional StudyNot yet recruitingNCT06876428