An interventional study of Titanium-prepared Platelet-Rich Fibrin and SCTG + CAF in Gingival Recession Types One(RT1) and Gingival Crevicular Fluid, sponsored by Ataturk University. Completed. Per ClinicalTrials.gov, last updated 2026-10-16.
Sponsored by Ataturk University · Not applicable, Interventional, and Treatment
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and coronally advanced flap (TPRF + CAF ) in the treatment of Miller class I and II gingival recessions.
413 studies on the registry are indexed under Gingival Recession; 98 are open to participants now.
This study's enrollment of 22 is below the median of 30 across 379 interventional studies indexed under Gingival Recession.
Browse Gingival Recession studies →Ataturk University is the lead sponsor of 454 studies on the registry; 123 are open to participants now.
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Exclusion Criteria:
Preoperative clinical measurements were taken and DOS samples were obtained from patients who had completed Phase I therapy. Titanium-prepared platelet-rich fibrin and coronally advanced flap (T-PRF + CAF) were performed.
Procedure: Titanium-prepared Platelet-Rich Fibrin
Preoperative clinical measurements were taken and DOS samples were obtained from patients who had completed Phase I therapy. Subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) were performed..
Procedure: SCTG + CAF
Blood samples (approximately 10 mL per tube) are drawn from the antecubital vein
connective tissue graft and coronally advanced flap
Percentage of Root Coverage
Description: Percentage of root coverage calculated as \[(baseline recession depth - postoperative recession depth) / baseline recession depth\] × 100. Recession depth is measured from the cemento-enamel junction (CEJ) to the most apical point of the gingival margin using a periodontal probe.
Time frame: Baseline and 6 months postoperatively
Gingival Crevicular Fluid (GCF) Biomarker Levels
Description: GCF levels of measured by ELISA, collected from the treated sites with paper strips.
Time frame: Baseline, 1, 3 and 6 months postoperatively
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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