An interventional study of Dietary intervention 1 and Dietary Intervention 2 in Dietary Habits and Endotoxemia, sponsored by University of Vienna. Completed at 1 site in Austria. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-01.
Sponsored by University of Vienna · Not applicable, Interventional, and Basic science
The aim of the present study is to determine the effect of non-nutritive sweeteners on intestinal barrier function and inflammatory markers in healthy subjects in comparison to mono- and disaccharides.
In the intervention study normal weight participants will receive beverages sweetened with non-nutritive sweeteners, mono- and disaccharides for a defined number of days. Before and after intervention parameters of intestinal barrier function will be assessed.
985 studies on the registry are indexed under Feeding Behavior; 178 are open to participants now.
This study's enrollment of 18 is below the median of 77 across 700 interventional studies indexed under Feeding Behavior.
Browse Feeding Behavior studies →University of Vienna is the lead sponsor of 49 studies on the registry; 16 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants receive a beverage with a defined amount of non-nutritive sweetener.
Other: Dietary intervention 1
Participants receive a beverage with a defined amount of non-nutritive sweetener.
Other: Dietary Intervention 2
Participants receive a beverage with a defined amount of monosaccharide.
Other: Dietary Intervention 3
Participants receive a beverage with a defined amount of disaccharide.
Other: Dietary Intervention 4
Participants receive a beverage with a defined amount of non-nutritive sweetener.
Participants receive a beverage with a defined amount of non-nutritive sweetener and maltodextrin.
Participants receive a beverage with a defined amount of monosaccharide.
Participants receive a beverage with a defined amount of disaccharide.
Changes in parameters of intestinal barrier function.
Changes in plasma endotoxin levels.
Time frame: 1 week
Changes in inflammatory markers.
Changes in IL-6 plasma levels (ng/ml).
Time frame: 1 week
Changes in blood pressure.
Changes in systolic and diastolic blood pressure
Time frame: 1 week
Changes in markers for glucose metabolism.
Changes in fasting glucose (mg/dl) and fasting insulin levels (mU/l)
Time frame: 1 week
Changes in markers for glucose metabolism.
Changes in fasting insulin levels (mU/l).
Time frame: 1 week
Changes in blood lipid levels.
Changes in triglyceride levels.
Time frame: 1 week
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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University of Vienna