Radboud University Medical Center: Endotoxemia trials

The registry lists 22 Endotoxemia studies with Radboud University Medical Center as lead sponsor. 1 are open to participants now and 0 have results posted.

Early Phase 1 1Phase 1 6Phase 2 1Phase 3 1Phase 4 3No phase 11(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human EndotoxemiaRecruitingNCT06624436Phase 4
• Determining the Fingerprint of Endotoxin ToleranceCompletedNCT06801873Not applicable
• The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor CellsCompletedNCT05570643Not applicable
• Effects of Cold Exposure and Breathing Techniques on Immune ResponseCompletedNCT03240497Not applicable
• The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human EndotoxemiaCompletedNCT02922673Not applicable
• Effects of Vasopressors on Immune ResponseCompletedNCT02675868Phase 4
• PK/PD of EA-230 During EndotoxemiaCompletedNCT02629874Phase 1
• Ticagrelor in Human Endotoxemia Response to Human EndotoxemiaCompletedNCT02612480Not applicable
• the Influence of Remote Ischemic Preconditioning on Inflammation During Human EndotoxemiaCompletedNCT02602977Early Phase 1
• Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1αCompletedNCT01978158Phase 1/2
• In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR IICompletedNCT01766414Phase 3
• The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human EndotoxemiaCompletedNCT01374711Not applicable
• Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human EndotoxemiaCompletedNCT01349699Not applicable
• Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental EndotoxemiaCompletedNCT01100996Not applicable
• The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human EndotoxemiaCompletedNCT01091571Phase 4
• The Effects of Atazanavir-induced Hyperbilirubinemia During Human EndotoxemiaCompletedNCT00916448Not applicable
• In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human EndotoxemiaCompletedNCT00785018Not applicable
• Anti-inflammatory Effects of GTS-21 After LPSCompletedNCT00783068Not applicable
• A Possible Therapeutic Role for Adenosine During InflammationCompletedNCT00513110Phase 1
• Pathophysiology and Clinical Relevance of Endotoxin Tolerance in HumansCompletedNCT00246714Phase 1
• Blockade of Vascular Potassium Channels During Human EndotoxemiaCompletedNCT00185003Phase 1
• Effect of Selective iNOS Inhibition During Human EndotoxemiaCompletedNCT00184990Phase 1