Endotoxemia: all 86 studies

Page 1 of 1. Open to participants first (8), then studies with results posted, then the rest; newest registration first within each.

• Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive FunctionRecruitingNCT07713641Not applicable
• Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety EvaluationNot yet recruitingNCT07661303Not applicable
• OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) StudyRecruitingNCT07419802
• Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial EndotoxaemiaNot yet recruitingNCT06972238
• Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human EndotoxemiaRecruitingNCT06624436Phase 4
• The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive DisorderRecruitingNCT06203015
• Different Dietary PatternsRecruitingNCT06147440Not applicable
• Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS)RecruitingNCT04920565Not applicable
• Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive ComponentsActive, not recruitingNCT05318183Not applicableResults posted
• Gut-level Antiinflammatory Activities of Green Tea in Metabolic SyndromeCompletedNCT03973996Not applicableResults posted
• Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic SyndromeCompletedNCT03624569Not applicableResults posted
• Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese AdultsCompletedNCT03413735Not applicableResults posted
• Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of DefibrotideCompletedNCT02876601Phase 4Results posted
• Vorapaxar in the Human Endotoxemia ModelCompletedNCT02875028Phase 4Results posted
• Sevelamer for Reducing Endotoxemia and Immune ActivationCompletedNCT01543958Phase 2Results posted
• Fenofibrate and Omega-3 Fatty Acid Modulation of EndotoxemiaCompletedNCT01048502Not applicableResults posted
• Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic ShockCompletedNCT01046669Not applicableResults posted
• The Genetics of Evoked Responses to Niacin and Endotoxemia: The GENE StudyCompletedNCT00953667Not applicableResults posted
• Lipid Infusion in Dialysis Patients With EndotoxemiaCompletedNCT00506454Phase 2Results posted
• Polyphenol Metabolism and Personalized Nutrition in Menopause (PolyPause).Active, not recruitingNCT07182370Not applicable
• Determining the Fingerprint of Endotoxin ToleranceCompletedNCT06801873Not applicable
• Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic IndexesTerminatedNCT06630572Phase 4
• Dietary Intervention to Reduce Metabolic EndotoxemiaCompletedNCT05776329Not applicable
• Elevated Levels of Antibodies to Endotoxin Core in Hemodialysis Patients With Peripheral Artery DiseaseCompletedNCT05752968
• The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor CellsCompletedNCT05570643Not applicable
• The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric SurgeryStatus unknownNCT05407090Not applicable
• Remove LPS RegistryWithdrawnNCT05260099
• Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier FunctionCompletedNCT04788680Not applicable
• Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19No longer availableNCT04352985
• Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk PreventionCompletedNCT04190706Not applicable
• Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in HumansCompletedNCT04130321Not applicable
• Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic SyndromeCompletedNCT04117802Not applicable
• Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease ModelCompletedNCT04064268Not applicable
• Gastro-intestinal and Hormonal Responses to Systemic Inflammatory DiseaseCompletedNCT04056286Not applicable
• Echocardiographic Changes After 3-hydroxy Butyrate+Whey IntakeCompletedNCT04037722Not applicable
• Cereals and Intestinal FunctionCompletedNCT04019457Not applicable
• Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary ProductsCompletedNCT03972878Not applicable
• Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label StudyCompletedNCT03901807Not applicable
• The Effect of Probiotics on Obesity. Metabolic Endotoxemia and InflammationCompletedNCT03883685Not applicable
• Investigating the Possible Link Between Habitual Diet, Physical Activity, Sleeping Patterns, Obesity Status and Age With Gut Bacterial Composition, Gut Barrier Function, Metabolic Endotoxemia, Systemic Inflammation and Glycaemic Control.Status unknownNCT03864107
• Effect of Cranberry and Agaves Extract on Microbiota and Intestinal HealthCompletedNCT03800277Not applicable
• Effects of Cranberry Powder Supplements on Gut Microbiota Diversity and Metabolic SyndromeCompletedNCT03754504Not applicable
• The Association Between Microbiota, Endotoxaemia and the Host Obesity/ Insulin Resistance (MiPOOP Study)CompletedNCT03665961
• Effect of Monosaccharides on Intestinal Barrier FunctionCompletedNCT03482284Not applicable
• ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight AdultsCompletedNCT03329781Not applicable
• Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute DiseaseCompletedNCT03319550Not applicable
• Effects of Cold Exposure and Breathing Techniques on Immune ResponseCompletedNCT03240497Not applicable
• A New Model of Acute Febrile DiseaseCompletedNCT03158363Not applicable
• The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human EndotoxemiaCompletedNCT02922673Not applicable
• Open-label Evaluation of Polymyxin B Hemoperfusion for Septic ShockTemporarily not availableNCT02825329
• Effects of Vasopressors on Immune ResponseCompletedNCT02675868Phase 4
• PK/PD of EA-230 During EndotoxemiaCompletedNCT02629874Phase 1
• Ticagrelor in Human Endotoxemia Response to Human EndotoxemiaCompletedNCT02612480Not applicable
• the Influence of Remote Ischemic Preconditioning on Inflammation During Human EndotoxemiaCompletedNCT02602977Early Phase 1
• The Role of Dietary Fat on Postprandial Endotoxemia in Healthy AdultsCompletedNCT02521779Not applicable
• Effect of Gemigliptin on Metabolic Endotoxemia and LipemiaCompletedNCT02186080Not applicable
• The Role of the Gut Microbiota in the Systemic Immune Response During Human EndotoxemiaCompletedNCT02127749Not applicable
• Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1αCompletedNCT01978158Phase 1/2
• Role Of Phospholipid Transfer Proteins (Pltp) On Endotoxemia Caused By Buccal InflammationCompletedNCT01950962Not applicable
• In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR IICompletedNCT01766414Phase 3
• Pharmacokinetics/Pharmacodynamics of NOX-H94 in the Human Endotoxemia ModelCompletedNCT01522794Phase 1
• Probiotic Sport StudyCompletedNCT01474629Not applicable
• The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human EndotoxemiaCompletedNCT01374711Not applicable
• Effects of Iron Loading and Iron Chelation Therapy on Innate Immunity During Human EndotoxemiaCompletedNCT01349699Not applicable
• Safety and Feasibility of an Endotoxemia ModelCompletedNCT01329965Phase 1
• Probiotics and EndotoxemiaCompletedNCT01176942Not applicable
• Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) InfectionCompletedNCT01107483
• Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental EndotoxemiaCompletedNCT01100996Not applicable
• The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human EndotoxemiaCompletedNCT01091571Phase 4
• Antiinflammatoric and Antioxidative Effect of Melatonin in Human EndotoxaemiaCompletedNCT01087359Phase 4
• The Effects of Hydrocortisone in Endotoxemia in Normal VolunteersCompletedNCT01064986Phase 1
• The Effects of Atazanavir-induced Hyperbilirubinemia During Human EndotoxemiaCompletedNCT00916448Not applicable
• In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human EndotoxemiaCompletedNCT00785018Not applicable
• Anti-inflammatory Effects of GTS-21 After LPSCompletedNCT00783068Not applicable
• The Effects of Epinephrine in Endotoxemia in Normal VolunteersCompletedNCT00753402Phase 1
• A Possible Therapeutic Role for Adenosine During InflammationCompletedNCT00513110Phase 1
• Study of Renal Blood Flow During Human EndotoxemiaStatus unknownNCT00413465Not applicable
• Type 2 Diabetes and the Effect of ProbioticsStatus unknownNCT00413348Not applicable
• Study of Gene Activity in Fat and Muscle in Diabetics and Healthy ControlsCompletedNCT00412906Not applicable
• Cerebral Blood Flow and Metabolism During Hypoxia and EndotoxemiaCompletedNCT00332267Not applicable
• Anti-Inflammatory Effect of Statins in the Human Endotoxin ModelCompletedNCT00309374Phase 1
• Ethnic Differences in the Inflammatory Response in Systemic InflammationCompletedNCT00284869Phase 1
• Pathophysiology and Clinical Relevance of Endotoxin Tolerance in HumansCompletedNCT00246714Phase 1
• Low-Dose Endotoxemia and the Acute Phase ResponseStatus unknownNCT00197899Not applicable
• Blockade of Vascular Potassium Channels During Human EndotoxemiaCompletedNCT00185003Phase 1
• Effect of Selective iNOS Inhibition During Human EndotoxemiaCompletedNCT00184990Phase 1

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