Drug
Brexpiprazole clinical trials
Also written OPC-34712 and Rexulti.
- studies test it
- 79
- open now
- 4
- in phase 3
- 49
- first study started
- 2008
Keep track of what changes. Save the brexpiprazole studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
79 studies that test it; most in 2013 (15)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 4 |
| 2010 | 3 |
| 2011 | 9 |
| 2012 | 3 |
| 2013 | 15 |
| 2014 | 3 |
| 2015 | 2 |
| 2016 | 2 |
| 2017 | 10 |
| 2018 | 10 |
| 2019 | 8 |
| 2020 | 3 |
| 2021 | 2 |
| 2022 | 1 |
| 2023 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 13
- Phase 2
- 15
- Phase 3
- 49
- Phase 4
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 69 · Other 10
Otsuka Pharmaceutical Development & Commercialization, Inc. (48) · H. Lundbeck A/S (9) · Otsuka Pharmaceutical Co., Ltd. (7) · Otsuka Beijing Research Institute (4) · Humanis Saglık Anonim Sirketi (1) · University of Massachusetts, Worcester (1) · University Health Network, Toronto (1) · University of Chicago (1)
Often tested with
Tested in the same studies.
Sertraline (3) · Androgen Antagonists (3) · Escitalopram (1) · Aripiprazole (1) · Moxifloxacin (1) · Cariprazine (1) · Risperidone (1)
Studies
Open first, then newest update. How each study uses brexpiprazole is read from its arms, and is right about nine times in ten.
Testing it · 79
- Brexpiprazole Treatment for Bipolar I DepressionRecruitingPhase 3Douglas Mental Health University InstituteNCT04569448Written as Brexpiprazole
- Longitudinal PET Imaging of Antipsychotic Binding to the Dopamine-3 Receptor in SchizophreniaNot yet recruitingPhase 1New York State Psychiatric InstituteNCT07715253Written as Brexpiprazole
- Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)RecruitingPhase 4Nova Scotia Health AuthorityNCT05017311Written as Brexpiprazole
- Brexpiprazole in Alcohol Use DisorderRecruitingPhase 2University of Colorado, DenverNCT04066192Written as Brexpiprazole
- Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescents With SchizophreniaCompletedPhase 1Otsuka Pharmaceutical Development & Commercialization, Inc.NCT02411695Written as Brexpiprazole (OPC-34712)
- Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With SchizophreniaCompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT03238326Written as Brexpiprazole
- Bioequivalence Study to Compare Brexpiprazole 4 mg Film Coated Tablets Versus RXULTI 4 mg Film Coated Tablet (Brexpiprazole)CompletedPhase 1Humanis Saglık Anonim SirketiNCT07266792Written as Brexpiprazole Film Coated Tablets
- Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum DisorderCompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04174365Written as Brexpiprazole
- Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSDCompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04124614Written as Brexpiprazole
- Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress DisorderCompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04174170Written as Brexpiprazole
- Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use DisorderCompletedPhase 4University of Massachusetts, WorcesterNCT03526354Written as Brexpiprazole
- Safety and Efficacy of Brexpiprazole in the Treatment of SchizophreniaCompletedPhase 3Otsuka Beijing Research InstituteNCT03874494Written as Brexpiprazole
- Brexpiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedPhase 2/3Otsuka Pharmaceutical Co., Ltd.NCT03620981Written as Brexpiprazole
- Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)CompletedPhase 2/3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04186403Written as Brexpiprazole
- Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedPhase 3Otsuka Pharmaceutical Co., Ltd.NCT03724942Written as Brexpiprazole
- A Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedPhase 2/3Otsuka Pharmaceutical Co., Ltd.NCT03697603Written as Brexpiprazole
- A Trial of Brexpiprazole in the Treatment of Borderline Personality DisorderCompletedPhase 2Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04100096Written as Brexpiprazole
- Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder for Subjects That Have Completed Participation in 331-201-00148CompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04258839Written as Brexpiprazole
- A Long-Term Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedPhase 3Otsuka Pharmaceutical Co., Ltd.NCT03737474Written as Brexpiprazole
- Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive DisorderCompletedPhase 4Otsuka Pharmaceutical Development & Commercialization, Inc.NCT04830215Written as Brexpiprazole
See all 79 studies that test brexpiprazole →
Given in every arm · 2 — brexpiprazole is usual care beside what is tested
- A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic MedicationCompletedPhase 2Astellas Pharma Global Development, Inc.NCT03557931Written as brexpiprazole
- Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)CompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT01360866Written as OPC-34712
Codes
What other systems call brexpiprazole · ClinicalTrials.gg INT000076
- MeSH (NLM) C000591922brexpiprazoleConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 2J3YBM1K8CBREXPIPRAZOLEConfirmed FDA, NLM, Wikidata
- RxNorm 1658314Confirmed FDA, Wikidata
- Wikidata Q2924764brexpiprazoleConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C166575BrexpiprazoleOne source FDA
- DrugBank DB09128One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000591922 | brexpiprazole | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 2J3YBM1K8C | BREXPIPRAZOLE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1658314 | — | Confirmed FDA, Wikidata |
| Wikidata | Q2924764 | brexpiprazole | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C166575 | Brexpiprazole | One source FDA |
| DrugBank | DB09128 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.