ClinicalTrials.gg
RecruitingNCT06606002Updated Aug 21, 2026

The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents

An interventional study of Group schema therapy and Treatment as Usual (TAU) in Borderline Symptoms and Borderline Personality Disorder, sponsored by Turku University Hospital. Recruiting at 1 site in Finland. Open to participants aged 15 Years to 22 Years. Per ClinicalTrials.gov, last updated 2026-08-21.

Sponsored by Turku University Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Aug 2025; still recruiting 1 year 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
64
Allocation
Randomized
Ages
15 Years to 22 Years
Sex
All
01

Study summary

The goal of this randomized and controlled trial is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms. The intervention utilizes self-recorded video material as an experiential method. The intervention comprises 30 group sessions and 8 individual sessions. Additionally, there are group sessions for the participants' parents. Participants in the control group receive treatment as usual.

Read the detailed description

The goal of this randomized and controlled intervention study is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms. Borderline personality disorder (BPD) is a severe and chronic mental health disorder, which features are typically detectable already in adolescence. BPD causes considerable suffering and functional impairment. Treatment recommendations emphasize treating BPD with targeted interventions already in adolescence, but evidence-based treatments in this age group are so far scarce.

The research sample consists of 32 adolescents who participate in a group schema therapy intervention and their 32 controls. The participants are adolescents aged 15-22 who are being treated either at the Adolescent Psychiatry Clinic or Psychiatry Clinic at the Turku University Hospital. The subjects meet at least three diagnostic criteria for BPD based on SCID-II assessment. Adolescents who are at serious suicide risk or with, for example, psychotic symptoms, or another disorder or symptom that endangers commitment to the intervention protocol, are excluded from the study.

The studied intervention is based on Farrell and Shaw's group schema therapy model. The experiential part of the model is strengthened utilizing videos, which are recorded by the participants (VideoTalk). The videos are used to support both individual and group work. The intervention is tailored to be developmentally sensitive for this age group and reinforced with a module to which the participants' parents participate.

The intervention comprises 30 weekly group sessions and 8 individual sessions. Eight adolescents participate in one group, and four groups are carried out during the study. The participants' parents have 9 group sessions, some of which the adolescents also participate in. The duration of the intervention is approximately one year. The control group receives treatment as usual.

Both the intervention and control groups response to the research questionnaires at five time points (baseline, 3 months, 6 months, 12 months, 2 years). The primary response variable is the change in the BPD symptoms between entering the study and the end of the intervention. As secondary response variables, changes in, for example, the participants' early maladaptive schemas, schema modes, and depressive and anxiety symptoms are assessed. After the end of the intervention, the study includes a one-year follow-up period and two years after the intervention, follow-up data is collected from the participants' medical reports. The study also includes qualitative sub-studies.

The intervention groups will be carried out during the years 2025-2027. A new group is always started overlapping with the previous group. Results regarding the primary response variable will be completed at the end of 2027. The entire research material will be completed at the end of 2029.

02

Conditions studied

  • Borderline Symptoms
  • Borderline Personality Disorder

Keywords

  • adolescents
  • borderline disorder
  • schema therapy
  • randomized controlled study
03

In context

Borderline Personality Disorder

278 studies on the registry are indexed under Borderline Personality Disorder; 70 are open to participants now.

This study's planned enrollment of 64 is close to the median of 70 across 221 interventional studies indexed under Borderline Personality Disorder.

Browse Borderline Personality Disorder studies →

Lead sponsor

Turku University Hospital is the lead sponsor of 287 studies on the registry; 67 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 22 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • The participant fulfills at least three diagnostic criteria for borderline personality disorder as assessed by means of the SCID-II structured clinical interview
  • The participant and the participant's parent(s) are able to commit to the research protocol for the entire duration of the study
  • The participant is able to participate in a research intervention in Finnish and fill out the study questionnaires in Finnish

Exclusion criteria

Exclusion Criteria:

  • The participant currently has psychotic symptoms or a serious risk of suicide
  • The participant has been diagnosed with an intellectual disability or an autism spectrum disorder
  • The main clinical diagnosis of the participant is a substance abuse disorder or substance use would endanger commitment to the research intervention
  • The participant has another illness or symptom that endangers the participant's ability to complete the study
  • The participant receives some other treatment specifically aimed at borderline personality disorder symptoms
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
64 participants (estimated)

Study arms

  • Experimental
    Group schema therapy

    The group schema therapy intervention includes 30 group sessions and 8 individual sessions for the participants, and 9 group sessions for the participants' parents.

    Behavioral: Group schema therapy

  • Active comparator
    Control

    Treatment as usual

    Behavioral: Treatment as Usual (TAU)

Interventions

  • BehavioralGroup schema therapy

    Group schema therapy based on the model by Farrell and Shaw, which is complemented with separate group sessions for the participants' parents

  • BehavioralTreatment as Usual (TAU)

    TAU typically comprises visits at the outpatient clinic with variable frequency and content

06

What researchers measure

Primary outcomes

  1. Borderline Symptom List - Short version

    Time frame: From enrollment to the end of treatment at 12 months

Secondary outcomes

  1. Young Schema Questionnaire Short Form 2 -Extended

    Time frame: From enrollment to the end of treatment at 12 months

  2. Schema Mode Inventory

    Time frame: From enrollment to the end of treatment at 12 months

  3. Patient Health Questionnaire-9

    Time frame: From enrollment to the end of treatment at 12 months

  4. Child and Adolescent Trauma Screen

    Time frame: From enrollment to the end of treatment at 12 months

  5. General Anxiety Disorder-7

    Time frame: From enrollment to the end of treatment at 12 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Aug 2025 (actual). Primary completion is estimated for Dec 2027, 28 months after the start.

Of 105 non-industry interventional studies with no phase under Borderline Personality Disorder, half reached primary completion within 35 months of starting (the median), counting those still running; a quarter within 24 and three quarters within 54. This study's planned 28 months is below that.

Counting every sponsor, half of 107 studies reached it within 35 months; a quarter within 24 and three quarters within 54.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 18, 2024
First posted
Sep 20, 2024
StartActual
Aug 1, 2025
Primary completionEst.
Dec 2027
CompletionEst.
Dec 2029
Last update
Aug 21, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 21, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06606002
Collaborators
University of Turku
Responsible party
Max Karukivi (Professor, Turku University Hospital) — Principal investigator
First posted
Sep 20, 2024
Start date
Aug 1, 2025
Primary completion
Dec 2027 (estimated)
Completion
Dec 2029 (estimated)
Last update
Aug 21, 2026

Study contacts

Max Karukivi, MD, PhD
Contact
max.karukivi@utu.fi
+358 2 313 0000
Max Karukivi, MD, PhD
principal investigator · University of Turku

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion